Volume 1, Issue 4

Javed Ali

pp. 199 · DOI: 10.4103/2230-973X.93002

Topical eye drops are the most common dosage form for treating disorder related to the anterior segment of the eye. However, a large amount of drug delivered through the eye drops is lost through tear drainage and associ…

Sagar Makwana, Biswajit Basu, Yogita Makasana, Abhay Dharamsi

pp. 200–206 · DOI: 10.4103/2230-973X.93004

Parenteral administration of pharmaceutical products is one of the most popular methods used to produce quick onset of action and also 100% bioavailability. Main problem occurs with the parenteral drug delivery is lack o…

Sanjay J Kshirsagar, Shrikant V Patil, Mangesh R Bhalekar

pp. 207–213 · DOI: 10.4103/2230-973X.93005

Introduction: A pulsatile drug delivery system is characterized by a lag time that is an interval of no drug release followed by rapid drug release. The purpose of this work was to develop hollow calcium alginate beads f…

Shantanu V Lale, Monu Goyal, Arvind K Bansal

pp. 214–221 · DOI: 10.4103/2230-973X.93007

Introduction: The purpose of the present study was to screen excipients such as amino acids and non-aqueous solvents for their stabilizing effect on catalase, a model protein, for lyophilization. The present study also i…

Santosh S Bhujbal, Sunita S Hadawale, Parag A Kulkarni, Jayant S Bidkar, Vidya A Thatte, Clarine A Providencia, Rupesh R Yeola

pp. 222–226 · DOI: 10.4103/2230-973X.93009

Background and Aim:Momordica charantia Linn. is traditionally used as a medicine for diabetes. The present investigation was aimed to formulate and evaluate transdermal patchesof Momordica charantia Linn. Materials and M…

Archana S Patil, Panchaxari M Dandagi, Vinayak S Masthiholimath, Anand P Gadad, Basavaraj K Najwade

pp. 227–223 · DOI: 10.4103/2230-973X.93010

Background: Hypertension shows circadian rhythm that there is a rise in pressure from the time of waking or before (about 4 to 8 a.m.), in most people. Conventional drug delivery system of captopril is inappropriate for …

Rachna Prasad, Sneh Anand, Veena Koul

pp. 234–239 · DOI: 10.4103/2230-973X.93011

Introduction: The effect of DC iontophoresis using low (0.2 mA/cm2) and high current density (0.5 mA/cm2) on transdermal permeation of methotrexate loaded into polyacrylamide hydrogel patch was investigated. Results: Flu…

Prabhakar Prabhu, Samip Shah, Shankar Gundad

pp. 240–246 · DOI: 10.4103/2230-973X.93008

Aim and Background: Domperidone is a dopamine antagonist with antiemetic properties having a plasma half life of 7-9 h with 15% oral bioavailability. In the present work transdermal patches of domperidone were prepared w…

Dasharath M Patel, Mehul J Patel, Ankit N Patel, Chhagan N Patel

pp. 247–254 · DOI: 10.4103/2230-973X.93006

Introduction:Present investigation describes an influence of ratio of Gelucire 43/01(hydrophobic) to hydroxypropyl methylcellulose K4M (HPMC K4M) (hydrophilic) and different fillers on release of famotidine from gastro-r…

Barkat Ali Khan

pp. 255 · DOI: 10.4103/2230-973X.93003

I have read the editorial note titled ‘Plagiarism: an editor’s concern’ by Dr Javed Ali and found it a bold and great decision by IJPI. Plagiarism is a serious contravention in modern age academic writing and research an…