Volume 2, Issue 1

Javed Ali

pp. 1 · DOI: 10.4103/2230-973X.96919

First and foremost I express heartfelt appreciation to all authors and reviewers of the first year ofInternational Journal of Pharmaceutical Investigation (IJPI) on behalf of the entire editorial board and the publisher.…

Gaurav Tiwari, Ruchi Tiwari, Birendra Sriwastawa, L Bhati, S Pandey, P Pandey, Saurabh K Bannerjee

pp. 2–11 · DOI: 10.4103/2230-973X.96920

Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are…

Swati Sareen, George Mathew, Lincy Joseph

pp. 12–17 · DOI: 10.4103/2230-973X.96921

This article is intended to combine recent literature on solid dispersion technology for solubility enhancement with special emphasis on mechanism responsible for the same by solid dispersion, various preparation methods…

Gergely Szakonyi, Romána Zelkó

pp. 18–25 · DOI: 10.4103/2230-973X.96922

In this paper we give an overview about the interaction of water molecules with pharmaceutical excipients. Most of these excipients are amorphous or partially amorphous polymers and their characteristics are very sensiti…

R Indira Prasanna, K Uma Sankari

pp. 26–33 · DOI: 10.4103/2230-973X.96923

Background: Glibenclamide (G) is a popular anti-diabetic drug, belonging to the class of sulfonylurea. The drug is widely used for treating type II diabetes but it undergoes first-pass effect. A novel aspiration in treat…

SB Shirsand, Sarasija Suresh, GG Keshavshetti, PV Swamy, P Vijay Prakash Reddy

pp. 34–41 · DOI: 10.4103/2230-973X.96924

Introduction: In the present study, mucoadhesive buccal bilayer tablets of atenolol were fabricated with the objective of avoiding first pass metabolism and to improve its bioavailability with reduction in dosing frequen…

Manju Nagpal, Rampal Rajera, Kalpana Nagpal, Pankaj Rakha, SK Singh, DN Mishra

pp. 42–47 · DOI: 10.4103/2230-973X.96925

Objective: The aim of present investigation is to enhancein vitro dissolution of poorly soluble drug glimepiride by preparing solid dispersions using modified gum karaya. Materials and Methods: Solid dispersions of drug …

Anil Kumar Singhal, Edwin E Jarald, Ahmad Showkat, Anwar Daud

pp. 48–51 · DOI: 10.4103/2230-973X.96926

Background: Moringa gum obtained from stem of the plant Moringa oleifera Lam. belonging to family Moringaceae. Number of naturally occurring polysaccharides obtained from plant (guar gum, inulin), animal (chitosan, chond…