jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
International Journal of Pharmaceutical InvestigationNOW IN
Article

Postmenopausal Hypertension and Blood Pressure Target Achievements using Monotherapy in a Tertiary Care Teaching Hospital, South India

Thangamani Subramani1★, Saravanan Kunchithapatham2, Sajeeth Chadappully Ismail1★ Corresponding author

  1. 1Department of Pharmacy Practice, Grace College of Pharmacy, Palakkad, Kerala, INDIA.
  2. 2Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, INDIA.

CORRESPONDENCE

Thangamani Subramani

Department of Pharmacy Practice, Grace College of Pharmacy, Palakkad, Kerala, INDIA.

thangamph@gmail.com

Received: 2020; Revised: 2020; Accepted: 2020.

Volume 12, Issue 2 · pp. 233–236 · PUBLISHED · DOI: 10.5530/ijpi.2022.2.41

View on IJPI original site ↗

ABSTRACT

Background:Prevalence of hypertension and scanty of evidences related to the clinical efficacy and safety of antihypertensive regimens among post menopausal women were almost negligible in India. So, the aim of the present study was aimed to evaluate the efficacy of antihypertensive as monotherapy in hypertensive postmenopausal women. Materials and Methods: A prospective observational study was conducted in Department of General Medicine at Karuna Medical College Hospital, Palakkad, Kerala for a period of November 2019 to October 2020. The patients were divided in to four groups according to the class (Angitensin Receptor Blockers (ARBs) or Calcium Channel Blockers (CCBs) or Diuretics or Beta Blockers) as monotherapy and their BP values were noted.Results:A total of 250 post menopausal hypertensive women were enrolled in this study. The patients achieved the goal on ARBs with 78% and CCBs with 69.5% was higher compared than BB (54.3%) and Diuretics (45.7%). ARBs and CCBs treated patients showed statistically significant differences in reduction of systolic blood pressure, Diastolic blood pressure, Pulse Pressure and Mean Arterial Pressure in hypertensive women. Conclusion:The two thirds of hypertensive post menopausal women are not being achieved the BP goal; those have more risk for cardiovascular disease and stroke.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Subramani, T., Kunchithapatham, S., & Ismail, S. C. (). Postmenopausal Hypertension and Blood Pressure Target Achievements using Monotherapy in a Tertiary Care Teaching Hospital, South India. International Journal of Pharmaceutical Investigation, 12(2), 233–236. https://doi.org/10.5530/ijpi.2022.2.41