jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
International Journal of Pharmaceutical InvestigationNOW IN
International Journal of Pharmaceutical Investigation volume 12, issue 2 cover
Search this issue

Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 12, Issue 2

· pp. 108–249 · 25 articles

Volume
12
Issue
2
Published
Pages
108–249
Articles
25
Sections
3
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI
Review ArticleOriginal ArticleCase Report

In this issue

Review Article

  1. Review

    An Extensive Review on Hydrogels in Pharmaceutical Drug Delivery Applications

    Subashini Rajaram, Senthil Rajan Dharmalingam, Vignesh Natarajan, Kaveena Ravi, Nivetha Shanmugam, Subbhashini Maruthamuthu Somasundaram

    pp. 108–112 · DOI: 10.5530/ijpi.2022.2.20 · Published

    In recent years pharmaceutical companies are directing towards designing new pharmaceutical dosage forms of existing medications. Recent breakthroughs have been the inclusion of pharmaco-therapeutic characteristics of dr…

  2. Review

    Phytochemistry and Pharmacological Activities of Plumbago indica L.: An Overview

    Bhatia Hemant, Kumar Dinesh, Ahuja Dharmendra

    pp. 113–116 · DOI: 10.5530/ijpi.2022.2.21 · Published

    Plumbago indica L. is a remedial herb species in the genus of Plumbago described by Linnaeus of the species of Plantarum, extensively in the hot and humid areas to use in the conventional structure of herbs. The distinct…

  3. Review

    Biological Potentials of Dibenzopyrrole Scaffolds: A Review

    Purushotham KN, TY Pasha, B Ramesh

    pp. 117–122 · DOI: 10.5530/ijpi.2022.2.22 · Published

    Numerous bioactive heterocyclic products containing carbazole nucleus showed pharmacological and biological significance. Carbazole have been found in several of significant drug like fragments which provided a precious …

  4. Review

    Novel Strategies in the Treatment of Acne: A Review

    Sujata Sharma, Shweta Vashist, Avneet Kaur Lamba, Saahil Arora, Sucheta s

    pp. 123–128 · DOI: 10.5530/ijpi.2022.2.23 · Published

    Skin break out and eruptions is a typical incendiary issue among people of all age groups, but most common in adolescents. Skin break out development is reliant upon mechanisms, including follicular hyper keratinization,…

  5. Review

    The Structure and Mechanism of Spike Protein, as Well as its Role in Numerous Viral Diseases

    Pranay Wal, Ankita Wal, Himangi Vig, Ashish Srivastava, Avnesh Kumar

    pp. 129–135 · DOI: 10.5530/ijpi.2022.2.24 · Published

    A spike protein is a protein that builds a huge spike that ejects from an enveloped virus’s membrane. The spike protein is the only virus membrane protein that enables the virus to penetrate through the cell. Spike Prote…

  6. Review

    Carbon Dot – An Updated Review

    Payel Mukherjee, Arindam Chakraborty, Manas Chakraborty, Goutam Mukhopadhyay

    pp. 136–140 · DOI: 10.5530/ijpi.2022.2.25 · Published

    These days, carbon dots (CDs) are the rising stars of nanomaterials. Carbon dots (CDs) are small carbon nanoparticles with the same type of surface passivation (less than 10 nm in size). Researchers found C-dots by accid…

  7. Review

    Comprehensions Keen on the Biology of Brain Tumors: Possibilities and Challenges

    Alaa Hamed Habib

    pp. 141–144 · DOI: 10.5530/ijpi.2022.2.26 · Published

    The word “tumor” is a Greek term that refers to a swelling or a lump. In modern medical terms, a tumor is usually an abnormal mass of cells and tissues which grows due to the abnormal division of cells. The unnatural div…

  8. Review

    Nanotechnology-based Therapeutic Strategies for Breast Cancer

    Majidah Aljadani

    pp. 145–150 · DOI: 10.5530/ijpi.2022.2.27 · Published

    Breast cancer is the most prevalent cancer among women and is considered a societal burden. The current treatment strategies are limited to chemotherapy, radiotherapy, and surgery, governed by the tumor’s size, stage, an…

  9. Review

    Phytochemical Based Nano Design for Cancer: A Recent Update

    Najat Binothman

    pp. 151–159 · DOI: 10.5530/ijpi.2022.2.28 · Published

    Despite exponential advancements in medical research, various types of cancer are increasing day by day and becoming a leading cause of mortality worldwide. The worldwide cancer burden has increased to 19.3 million new c…

Original Article

  1. Article

    Spectroscopic Analysis of Lagos spinach- seed (Celosia argentea Linn.)

    Falguni Saraswat, Mukeshkumar Nariya, Vinay J Shukla

    pp. 160–164 · DOI: 10.5530/ijpi.2022.2.29 · Published

    Background:Celosia argentea Linn. (C. argentea) commonly known as Cock’s Comb. It’s a leading leafy vegetable used for treatment of anti inflammatory, antioxidant and possessing immunostimulating activities. This species…

  2. Article

    A Novel Prognostic Biomarker with Potential of High Diagnostic Accuracy in Pulmonary Tuberculosis: An in silico Study

    Bashir Ahmad Sheikh, Basharat Ahmad Bhat, Rakeeb Ahmad Mir, Zahoor Ahmad, Manzoor Ahmad Mir

    pp. 165–172 · DOI: 10.5530/ijpi.2022.2.30 · Published

    Background:Due to the fact that pulmonary tuberculosis (PTB) is a highly infectious disease characterized by high herd susceptibility and hard to be treated. Cytokines have a crucial role in eliciting protective and path…

  3. Article

    Synthesis and Study of Antibacterial Effect of 3,4 -Diaryl-6-oxo 1-phenyl-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

    Kailas Rangnath Labhade

    pp. 173–177 · DOI: 10.5530/ijpi.2022.2.31 · Published

    Objectives:The present study was focused on environment friendly synthesis of cynopyridone compounds. New improved, three component, one-pot, solvent-free method was successfully developed for the synthesis of 3,4 -diary…

  4. Article

    Efficient Euphorbia hirta Phytosomes for in vitro Antiasthmatic Activity

    Poonam Karekar, Suresh Killedar

    pp. 178–182 · DOI: 10.5530/ijpi.2022.2.32 · Published

    Background: The purpose of this study was to assess the antiasthmatic activity of Euphorbia hirta extract and Euphorbia hirta phytosomes in an in vitro anti-asthmatic model. Materials and Methods:The phytosomes were test…

  5. Article

    Simultaneous Estimation of Lamivudine, Didanosine and Efavirenz in Bulk and their Formulation by UPLC

    Srivani Mallepelli, Sreelatha Kamera, Achaiah Garlapati

    pp. 183–190 · DOI: 10.5530/ijpi.2022.2.33 · Published

    Objectives:To develop a simple, rapid, reliable and precise RP-UPLC method for the simultaneous estimation of lamivudine, didanosine and efavirenz in bulk and its tablet dosage forms. Materials and Methods:The chromatogr…

  6. Article

    Formulation Development of Sustain Release Tablets of Lornoxicam using Chemically Modified Xanthan Gum

    Sandip Ashok Murtale, Prakash Goudanavar, Ankit Acharya, Jayatheertha Lokapur

    pp. 191–198 · DOI: 10.5530/ijpi.2022.2.34 · Published

    Background: In the medical and pharmaceutical fields, man has made successful use of natural origin things for millennia. Natural medications and excipients have piqued the interest of the entire globe today. Obtained fr…

  7. Article

    A Novel Approach of Leflunomide Nanoemulgel for Topical Drug Delivery System

    Vivek Verma, T S Easwari

    pp. 199–204 · DOI: 10.5530/ijpi.2022.2.35 · Published

    Objectives: This research’s primary goals are Leflunomide (LFD) nanoemulgel formulation and characterization for topical administration. Materials and Methods:A pseudo ternary phase diagram was created utilizing castor o…

  8. Article

    Spray Dried Mucoadhesive Microparticles of Donepezil with Chitosan and Carbopol in Alzheimer’s Disease

    Sachin Manik Jadhav, Sagar Kumar Mishra

    pp. 205–210 · DOI: 10.5530/ijpi.2022.2.36 · Published

    Background:The traditional oral formulation for Alzheimer’s disease treatment has the drawbacks of first-pass metabolism, plasma protein binding, and poor blood-brain barrier penetration. This study was conducted to esta…

  9. Article

    In vitro Anti-inflammatory Activity and Acute Oral Toxicity Study of Gold Nanoparticles Generated from Stem Extract of Tinospora cordifolia

    Koliyote Sheeja, Shaji Jessy

    pp. 211–215 · DOI: 10.5530/ijpi.2022.2.37 · Published

    Introduction:Synthesis of gold nanoparticles (GNPs) from various biological systems have been reported, but amongst them biosynthesis of GNPs from plants is considered as the most suitable method. The aim of this study w…

  10. Article

    Pharmacological Screening of Gentisic acid for Antidepressant Activity in Unstressed and Stressed Mice

    Sudha Bansal, Dinesh Dhingra

    pp. 216–222 · DOI: 10.5530/ijpi.2022.2.38 · Published

    Background: Gentisic acid has been reported to show neuroprotective effect. But its effect on depression is not available in the literature. So we evaluated the effect of this compound on depressive behavior in unstresse…

  11. Article

    Hepatoprotective Potential of Ethanolic Extract of Capparis zeylanica Root on Paracetamol-induced Hepatotoxicity in Rats

    Raghunandan Hota, Bikash Kumar Nanda, Biswaranjan Behera, Chandan Das, Ashutosh Meher

    pp. 223–227 · DOI: 10.5530/ijpi.2022.2.39 · Published

    Background:Capparis zeylanica (Capparaceae), a climbing shrub find its distribution throughout the different parts of India. Traditionally, it is used in the treatment of snake bite, small pox, stomach ulcers, piles, cho…

  12. Article

    Antibacterial and Antibiofilm Activities of Natural Herbs against Methicillin Resistant Staphylococcus aureus in Pus from Scabies

    Smritikana Biswas, Abhijit Ghosh, Giri Biplab

    pp. 228–232 · DOI: 10.5530/ijpi.2022.2.40 · Published

    Introduction: Mite Sarcoptes scabiei causes scabies which is a communicable skin infection and it promotes a suitable niche for microorganisms for their growth and development to cause secondary infection. This study was…

  13. Article

    Postmenopausal Hypertension and Blood Pressure Target Achievements using Monotherapy in a Tertiary Care Teaching Hospital, South India

    Thangamani Subramani, Saravanan Kunchithapatham, Sajeeth Chadappully Ismail

    pp. 233–236 · DOI: 10.5530/ijpi.2022.2.41 · Published

    Background:Prevalence of hypertension and scanty of evidences related to the clinical efficacy and safety of antihypertensive regimens among post menopausal women were almost negligible in India. So, the aim of the prese…

  14. Article

    Assessment of Various Maternal Risk Factors and Treatment Approaches for Neonatal Jaundice in a Tertiary Care Hospital

    Shima Ghavami, Vithya Thirumoorthi

    pp. 237–241 · DOI: 10.5530/ijpi.2022.2.42 · Published

    Background:The study objectives were to evaluate the neonatal jaundice treatment approach and identify various risk factors associated with the occurrence of neonatal jaundice.Materials and Methods:A prospective study wa…

  15. Article

    A 4-Year Prospective Study on Anti-fungal and Reserved Antimicrobial Drugs under Antimicrobial Stewardship Program

    Ketan Kailash Khelwade, Shrikalp D, Bhavini S

    pp. 242–246 · DOI: 10.5530/ijpi.2022.2.43 · Published

    Introduction: In 2018 and 2021, CIMS hospital conducted an audit to analyse the quality of antifungal use. We conducted a follow-up audit after four years of the antifungal stewardship programme (AFS) to evaluate the pro…

Case Report

  1. Article

    Unani Management of Recurrent Bartholin’s Gland Cyst: A Case Report

    Farzana Mohammed Umar Ziard Noorul Farzana, Tharique Isamail

    pp. 247–249 · DOI: 10.5530/ijpi.2022.2.44 · Published

    In female reproductive system, Bartholin’s glands are one of the essential organs. In 17th century, Danish anatomist, Casper Bartholin first described about Bartholin’s cyst. at the posterior introitus of vagina two pea-…