jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
International Journal of Pharmaceutical InvestigationNOW IN
International Journal of Pharmaceutical Investigation volume 12, issue 1 cover
Search this issue

Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 12, Issue 1

· pp. 1–106 · 19 articles

Volume
12
Issue
1
Published
Pages
1–106
Articles
19
Sections
3
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI
Review ArticleOriginal ArticleCase Report

In this issue

Review Article

  1. Review

    Tamoxifen: An Investigative Review for Nano Dosage Forms and Hyphenated Techniques

    Rajeshri Dineshbhai Patel, Yamini Anilbhai Bhalani, Dhruti Sanjaybhai Sudani Sudani, Lipsa Ashvinbai Vachhani

    pp. 1–6 · DOI: 10.5530/ijpi.2022.1.1 · Published

    Tamoxifen (TAM), a non-steroidal antiestrogen, has revolutionized female breast cancer treatment. The mechanism involves is to compete with 17β-estradiol (E2) at the receptor site and blocking the promotional role of E2 …

Original Article

  1. Article

    Phytochemical and Molecular Docking Studies on Indigenous Herbs Glycyrrhiza glabra, Terminalia chebula and Hamdard joshanda

    T. H. Mohamed Ahadu Shareef, Mohamed Divan Masood

    pp. 7–14 · DOI: 10.5530/ijpi.2022.1.2 · Published

    Background:Glycyrrhiza glabra,Terminalia chebulaandHamdard joshandais used as a traditional home medicine in developing countries that is easily available for a lesser cost with no side effects. These medicine decoctions…

  2. Article

    Quantitative Phytochemical Analysis and in vitro Study of Antioxidant and Anti-inflammatory Activities of Aegle marmelos Fruit with Peel and without Peel: A Comparative Evaluation

    Swami Pooja Ganpat, Singhavi Dilesh Jagdish, Ganjiwale Rajendra Onkarappa

    pp. 15–19 · DOI: 10.5530/ijpi.2022.1.3 · Published

    Background:Aegle marmelos is an important ethnomedicinal plant that is found commonly in India and other Asian countries. The peel of the fruit is hard and is often discarded as waste. However, a few studies have shown t…

  3. Article

    Antibacterial, Antifungal, Cytotoxic and Genotoxic Activities of Different Extracts of Arabic and Myrrh Gums

    Imène Becheker, Ali Becheker, Mohamed Akram Melakhessou, Salah Eddine Marref, Hajira Berredjem

    pp. 20–27 · DOI: 10.5530/ijpi.2022.1.4 · Published

    Background: The Pharmaceutical companies are very interested in the discovery of new natural bioactive molecules with an impoortant effect and less toxicity, in order to replace old drugs, especially antibiotics which ha…

  4. Article

    Moringa oleifera Methanolic Extract Induces Apoptosis in Human Breast Cancer Cells

    Kiran Kharat, Sonal Jawale, Amol R Kharat, Preetha Achary, Vinod R Ragade

    pp. 28–32 · DOI: 10.5530/ijpi.2022.1.5 · Published

    Background: Moringa oleifera Lam. (Family: Moringaceae), commonly known as ‘drumstick tree’ is beneficial to obtain sustenance as a food source and applied as a traditional medicine. The therapeutic potential ofMoringa o…

  5. Article

    Biochemical and Physicochemical Characterization of Phytochemical from Hygrophila schulli (Buch. Ham.) M.R. Almeida and S.M. Almeida

    Murugan Sellappan, Kumar Giriappa Venkatesh

    pp. 33–38 · DOI: 10.5530/ijpi.2022.1.6 · Published

    Background: Plants are an important source of medicine. Most of the plants are studied for their therapeutic values and to treat various diseases. Hygrophila schulli is one of the important medicinal plants belonging to …

  6. Article

    Effect of Dill Seed Cake on Dyslipidemia and Hormonal Imbalance against High Fructose-diet Induced Obesity in Rats

    Ankita Awasthi, Bhaskar Kumar Gupta, Papiya Bigoniya

    pp. 39–45 · DOI: 10.5530/ijpi.2022.1.7 · Published

    Background: The present study was investigated about the anti-obesity effect of dill seed cake on rats fed with high fructose diet. Materials and Methods:45 days experimental study of high fructose diet feeding induced o…

  7. Article

    Hepatocyte Growth Factor and Betacellulin Gene Expression for Treating Diabetes: In vitro analysis

    Yash Desai, Micky Patel, Ravikiran Panakanti

    pp. 46–50 · DOI: 10.5530/ijpi.2022.1.8 · Published

    Background:Diabetes mellitus is a fast spreading metabolic disease in both developed and developing countries owing to genetic predisposition, lifestyle and or environmental conditions. Recombinant insulin used for manag…

  8. Article

    A Reverse Phase Stability Indicating HPLC Method Development for Estimation Assay of Benzyl Alcohol and Glycopyrrolate in Glycopyrrolate Injection

    Mukkala Prasada Reddy, Obireddy Sreekanth Reddy, Marata Chinna Subbarao Subha

    pp. 51–55 · DOI: 10.5530/ijpi.2022.1.9 · Published

    Background:The present work is focused on developing a simple stability indicating method for the estimation of the assay of benzyl alcohol and glycopyrrolate in glycopyrrolate injection using reverse high performance li…

  9. Article

    Development and Validation of Fast and Robust Stability Indicating RP-HPLC Method for Simultaneous Estimation of Tolperisone Hydrochloride and Etoricoxib in Pharmaceutical Dosage Form

    Ravisinh Vikramsinh Solanki, Ravi Bharatkumar Patel, Rajeshkumar Kanubhai Patel, Riya Alpeshkumar Sheth

    pp. 56–61 · DOI: 10.5530/ijpi.2022.1.10 · Published

    Objectives:A precise, accurate and selective stability-indicating reverse phase high performance liquid chromatographic assay method has been developed for the simultaneous quantitative determination of Tolperisone hydro…

  10. Article

    Physicochemical, Phytochemical and HPTLC Analysis of a Novel Combined Herbal Formulation

    Mohamed Shiffa, M Aslam, MH Kazmi, Syed Mansoor Ali, Nazeem Fahamiya, Mohammad Mahfuzul Haque

    pp. 62–65 · DOI: 10.5530/ijpi.2022.1.11 · Published

    Background: Cinnamomum zeylanicum (Darchini), Alpinia galanga (Khulanjan), and Withania somnifera (Asgand) have been used in joint diseases by Unani scholars since long. The combination of these ingredients may be more e…

  11. Article

    Alpha-Asarone Ameliorates Cisplatin Induced Hepatotoxicity via Reducing the Oxidative Stress in Experimental Animals

    Prafulla R Tathe, Rakeshkumar Jat, Amjadkhan Pathan, Kailas Biyani

    pp. 66–69 · DOI: 10.5530/ijpi.2022.1.12 · Published

    Background: The aim of present study was to find protective effect of α-asarone in cisplatin-induced hepatotoxicity in experimental rats. Materials and Methods: The rats were divided into 5 groups at randomly. Cisplatin …

  12. Article

    Evaluation of Calcium Oxalate Crystal Nucleation, Aggregation and Phytochemical Compositions of Cissus adnata Roxb. and Cissus discolor Blume

    Dollyca Ningombam, Toijam Sanjeev Lyngdoh, Maibam Damayanti Devi

    pp. 70–74 · DOI: 10.5530/ijpi.2022.1.13 · Published

    Background: From time immemorial medicinal plants are used in treating urolithiasis in ayurvedic system and other forms of traditional health practitioners. In Manipur, local traditional health practitioners used Cissus …

  13. Article

    In vitro Kinetic Release Study, in vivo Hydration and Moisturizing Effect of Peel-off Oil-in-Water (O/W) Nanoemulsion Containing Kojic Monooleate for Topical Application

    Nur Farzana Jaslina, Nur Hana Faujan, Rosfarizan Mohamad, Siti Efliza Ashari

    pp. 75–81 · DOI: 10.5530/ijpi.2022.1.14 · Published

    Background: Kojic monooleate (KMO) contains tyrosinase inhibitor and exhibits strong antioxidant activity makes it a good candidate to be incorporated into a formulation for topical application. A peel-off was chosen to …

  14. Article

    Wound Healing Dressing System for Diabetic Wounds Based on Curcumin and Syringic Acid

    Rahul Padalkar, Ashwini Madgulkar, Rohit Kharade

    pp. 82–86 · DOI: 10.5530/ijpi.2022.1.15 · Published

    Background: This work is based on the development of a wound healing dressing system for diabetic wounds using curcumin and syringic acid. A diabetic wound differs from a normal wound in respect to many pathophysiologica…

  15. Article

    Optimization and Analysis of Xanthan Gum and Hypromellose Combined Matrices for Extended Release of Ranolazine Using Quality by Design

    C Sowmya, V Lava Kumar, Bishnu Adhikari

    pp. 87–92 · DOI: 10.5530/ijpi.2022.1.16 · Published

    Background:Xanthan gum (XG) is a natural polymer with numerous uses. But its poor tableting and release charact1eristics reduce its usage as a tablet matrix former. Hence, the aim of the study is to improve the quality o…

  16. Article

    Fabrication and Characterization of Famotidine Solid Lipid Nanoparticles Using Hot Emulsification Method for Bioavailability Enhancement

    Singh Jagpal, Mahendra Singh

    pp. 93–96 · DOI: 10.5530/ijpi.2022.1.17 · Published

    Objective:The objective of this paper was to fabricate and increase the effectiveness of the formulation of Solid lipid nanoparticle (SLN) on improving the oral bioavailability of Famotidine. Methods: In this study, ultr…

  17. Article

    Comparative Mapping of World and Indian Nanocellulose Research Output during the last Decade: A Scientometric Study

    Mallikarjun Kappi, Murthy Chavali, Chaman Sab M, KK Mueen Ahmed

    pp. 97–103 · DOI: 10.5530/ijpi.2022.1.18 · Published

    Aim:The present study aims to trace out the comparative mapping of World and Indian Nanocellulose research output. Methodology: The Science Citation Index (SCI) of Web of Science (WoS) core collection was used data extra…

Case Report

  1. Article

    Case Report: Paraquat Poisoning Associated Multiple Organ Dysfunction Syndrome

    Sahithi Maroju, K Krishna Sumanth

    pp. 104–106 · DOI: 10.5530/ijpi.2022.1.19 · Published

    An 18-year female presented with an alleged history of the conception of liquid paraquet of an unknown quantity on 3rd August 2021. On examination, the patient was unconscious and disoriented. She was further diagnosed w…