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Past Work Done on the Matrix Tablets: A Quick Reference for the Research Beginner in Sustained-release Dosage Forms

Hindustan Abdul Ahad1★, Haranath Chinthaginjala2, Bake Meharajunnisa2, Nayakam Vandana1, Renuka Gudisipalli1, Peddapothula Nikhila1★ Corresponding author

  1. 1Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA.
  2. 2Department of Pharmaceutics, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA.

CORRESPONDENCE

Hindustan Abdul Ahad

Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K.R. Palli Cross, Ananthapuramu, Andhra Pradesh, INDIA.

abdulhindustan@gmail.com

Received: 28-01-2023; Revised: 17-02-2023; Accepted: 02-04-2023.

Volume 13, Issue 3 · pp. 367–372 · PUBLISHED · DOI: 10.5530/ijpi.13.3.047

View on IJPI original site ↗

ABSTRACT

Matrix tablets are also referred to as sustained-release, controlled-release, or prolonged-release extended-release tablets, which will prolong the duration of the release of drug content into the systemic circulation. This work was to collect matter about polymers so far tried in making matrix tablets. Due to the prolonged duration of release, this may increase the bioavailability of the drug. They are made with various polymers, starting with cellulose, its derivatives, and plant gums or mucins. This data was obtained by viewing to peer-reviewed journals and magazines. These tablets can be prepared by direct compression of a blended mixture containing polymers, blending agents, glidants, and other additives. The blend was made as granules and compressed as tablets. The matrix tablets are sustained drug release forms and show better action. The study revealed that the matrix tablet is a simple method for extending drug release for a prolonged period

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    Ahad, H. A., Chinthaginjala, H., Meharajunnisa, B., Vandana, N., Gudisipalli, R., & Nikhila, P. (). Past Work Done on the Matrix Tablets: A Quick Reference for the Research Beginner in Sustained-release Dosage Forms. International Journal of Pharmaceutical Investigation, 13(3), 367–372. https://doi.org/10.5530/ijpi.13.3.047