Volume 13, Issue 3

Original Article(continued)

1. Article

   Design, Optimization and Characterization of Newer Herbal Tablet Containing Momordica dioica Extract

   Subhashchandra K. Patel, Hirenkumar R. Chaudhary, Tejal R. Gandhi

   pp. 538–547 · DOI: 10.5530/ijpi.13.3.067 · 2023

   Background: Momordica dioica (MD) is called the teasle gourd, spiny gourd, and kakrol. Among the important phytochemicals present in MD include alkaloids, flavonoids, phenolics, tannins, saponins, steroids, glycosides, a…

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2. Article

   Design and in silico Prediction of New Methylenedioxyphenyl Derivatives as DNA Topoisomerase II Inhibitors

   Swati Rathore, Maadhu Reddemma, Neha Rai, Richa Tripathy Tiwari, Shaheen Begum, Shailendra Patil, Asmita Gajbhiye Patil

   pp. 548–558 · DOI: 10.5530/ijpi.13.3.068 · 2023

   Background:Cancer is the world’s leading cause of death; more than ten million people die from cancer each year. Rate of morbidity and mortality is increasing day by day. As a result, utilizing chemoinformatics technique…

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3. Article

   Pharmasure - A Tool to Reduce Mortality and Morbidity Rate

   Sumit Shashikant Mude, Mukesh Tatyarao Mohite

   pp. 559–565 · DOI: 10.5530/ijpi.13.3.069 · 2023

   Purpose: In the last decade over 17.46 million people in India died due to wrong medication and drug-drug interaction. In fact, Drug-drug interaction is the 4th leading cause of death in India. Medications used in COVID-…

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4. Article

   Synthesis, Characterization and Pharmacological Evaluation of Ultra Short Dipeptides as Antimicrobial and Anticancer Agents

   Neha Rai, Swati Rathore, Richa Tripathy Tiwari, Shailendra Patil, Asmita Gajbhiye

   pp. 566–573 · DOI: 10.5530/ijpi.13.3.070 · 2023

   Background:The biological compounds known as peptides are found in nature. They are peptide (amide) links that connect short chains of amino acid monomers. Nowadays, peptide-based therapeutic treatments are employed beca…

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5. Article

   Stability Indicating HPTLC Method Development and Validation for Quantification of Favipiravir in Bulk and Commercial Film Coated Tablet

   Aishwarya Ramchandra Balap, Aniket Padmakant Dudhe

   pp. 574–581 · DOI: 10.5530/ijpi.13.3.071 · 2023

   Introduction:Favipiravir was remerging antiviral drug in the beginning era of COVID-19 Pandemic as an urgent therapeutic alternative to treat COVID-19. Literature survey reveals that there is no any reported stability in…

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6. Article

   Simultaneous Estimation of Lamivudine, Tenofovir Disoproxil Fumarate and Efavirenz in Bulk and Tablet Dosage Form by Cramer’s Rule

   Atul Baravkar, Gandhi Santosh, Bawaskar Namrata, Vitthal Chopade, Makarand Puri, Vishnu Neharkar, Ramdas Kale, Dattatray Kature, Rahul Jadhav, Manisha Patil, Reshma Devkate, Alfa Jain, Deepali Kadam, Amol Khedkar, Sachin Vijapure, Nilima Wani, Ganesh Shinde

   pp. 582–587 · DOI: 10.5530/ijpi.13.3.072 · 2023

   Background:Cramer's rule is one of the significant techniques applied to settle an arrangement of conditions. In this rule, the upsides of the factors in the framework are to be determined utilizing the determinants of n…

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7. Article

   Validated Reverse-Phase HPLC Method for Quantification of Fluconazole and Quercetin in Pharmaceutical Formulation

   Hitesh G. Raval, Ujashkumar A. Shah, Hirak Kumar Joshi, Vaishali T. Thakkar

   pp. 588–594 · DOI: 10.5530/ijpi.13.3.073 · 2023

   Objectives: Fluconazole (FCZ) and Quercetin (QCT) in pharmaceutical dosage form were simultaneously quantified using a sensitive, accurate, robust, and précised Reverse Phase-HPLC Method. Materials and Methods: RP-HPLC m…

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8. Article

   Analytical Method Development and Validation of Rivastigmine in its Pure and Pharmaceutical Dosage form Using UPLC

   Aarthi Kommu, Raja Sundararajan

   pp. 595–604 · DOI: 10.5530/ijpi.13.3.074 · 2023

   Objectives: For the quantification of rivastigmine in both its pure form and pharmaceutical formulation, an ultra-performance liquid chromatography method with high speed and sensitivity was created and validated. Materi…

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9. Article

   High-Cited Papers in Global COVID-19 Vaccine Research

   B.M. Gupta, K.K. Mueen Ahmed, Mallikarjun M Kappi, Madhu Bansal, Jivesh Bansal

   pp. 605–616 · DOI: 10.5530/ijpi.13.3.075 · 2023

   Background and Aim:The coronavirus disease 2019 (COVID-19) virus pandemic is still ravaging the world with its ongoing resurgence and continuous mutation, suggesting the need for continuous research on safe and effective…

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10. Article

    Analytical Method Development and Validation for Determination of Valganciclovir by Using RP-HPLC

    Gaddam Venkata Abhigna, Raja Sundararajan

    pp. 617–624 · DOI: 10.5530/ijpi.13.3.076 · 2023

    Objectives:A novel, precise, and accurate RP-HPLC method was developed and validated for the determination of valganciclovir in pure and medicinal dose form. Cytomegalovirus infections were treated with the antiviral med…

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11. Article

    Evaluation of the Antibiotic Prescribing Pattern and Related Adverse Drug Reaction in an India Tertiary Care Hospital: A Prospective Observational Study

    Manouchehr Khanipour, Mina Shahraki Mohammadi, Balakeshwa Ramaiah

    pp. 625–631 · DOI: 10.5530/ijpi.13.3.077 · 2023

    Introduction:Antibiotics have important roles in human health, whereas irrational use of antibiotics is a major problem of public health that leads to resistance and ADRs. This study aimed to evaluate the prescribing pat…

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12. Article

    Prevalence of Musculoskeletal Disorders and Health Related Quality of Life (HRQoL) in Patients Visiting Secondary Healthcare Setting

    Uppara Veerendra, Palagiri Akbar Basha, Byragani Naga Bindu, Deti Pruthvi Bhushan, Gutam Venkata Kalyani

    pp. 632–640 · DOI: 10.5530/ijpi.13.3.078 · 2023

    Introduction:Musculoskeletal disorders are injuries or illnesses that affect the muscles, nerves, tendons, joints, cartilage, and spinal discs. These disorders are characterized by a loss of physical function in the body…

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13. Article

    Monitoring Adverse Medication Reactions: Aiding Pharmacovigilance at a Hospital Providing Secondary Care

    Kommanuru Venkata Ramakrishna Teja, Yiragamreddy Padmanabha Reddy, Nayakanti Devanna

    pp. 641–645 · DOI: 10.5530/ijpi.13.3.079 · 2023

    Introduction:Although adverse drug reaction (ADR) monitoring is widely known, it is not practised in underdeveloped nations due to a lack of awareness and the absence of a central coordinating agency. The recent implemen…

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14. Article

    In vitro Anti-cancer Activity of Nandhi mezhugu (NM) in Ovarian Cancer Cell Line (PA-1) Using MTT Assay

    Glara Anest Francis, Sureka Arumugam, Sabari Girija Navaneetha Krishnan, Ramamurthy Murugan, Christian Gnanaraj Johnson, Moses Erin Johnson Christian, Meenakumari Ramasamy

    pp. 646–650 · DOI: 10.5530/ijpi.13.3.080 · 2023

    Introduction: Ovarian cancer is the fifth most common cause of cancer which causes more deaths than any other cancer of the female reproductive system because there is no effective screening and most women are diagnosed …

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15. Article

    Investigation of Phytochemical Profile of Ethanolic Extract of Elaeocarpus ganitrus and Desmostachya bipinnata

    Harish Gupta, Girendra Kumar Gautam

    pp. 651–655 · DOI: 10.5530/ijpi.13.3.081 · 2023

    The present study is designed to evaluate the phytochemical profile of Elaeocarpus ganitrus and Desmostachya bipinnata. Extraction was performed using ethanol as a solvent for both the plants. Preliminary phytochemical s…

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16. Article

    Simultaneous Estimation of Gallic Acid, Vasicine, Pterostilbene and Piperine Using RP-HPLC Method from Ayurvedic Proprietary Formulations

    Sanjay U Nipanikar, Pravin S Surwade, Ankita R Kasabe, Priyanka B Patil, Sachin A Upasani

    pp. 656–665 · DOI: 10.5530/ijpi.13.3.082 · 2023

    Introduction: A simple, accurate, precise, sensitive, and validated RP-HPLC method was developed for simultaneous estimation of Gallic Acid (GA), Vasicine (VS), Pterostilbene (PTS) and Piperine (PP) from Ayurvedic Propri…

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17. Article

    Preparation and Characterization of Mucoadhesive Proniosomal Gel of Curcumin with Thiolated Chitosan for the Treatment of Oral Mucositis

    Shweta Vashist, Manoj M. Gadewar

    pp. 666–672 · DOI: 10.5530/ijpi.13.3.083 · 2023

    Aim:Oral mucositis is a problem which is found in a cancer patient, taking chemotherapy radiation therapy. This work aims to formulate a mucoadhesive curcumin proniosomal gel by using thiolated chitosan for buccal delive…

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18. Article

    Drug Utilization Evaluation of Antidiabetic Drugs in a Tertiary Care Teaching Hospital: Analysis from a Randomized Controlled Study

    Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Bharati Kangrali

    pp. 673–679 · DOI: 10.5530/ijpi.13.3.084 · 2023

    Background: Diabetes Mellitus (DM) is a chronic metabolic condition characterized by high blood glucose levels and changes in carbohydrate, lipid and protein metabolism due to insulin secretion, action, or both.1 Diabete…

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