International Journal of Pharmaceutical Investigation
Volume 2, Issue 3
· pp. 97–168 · 9 articles
- Volume
- 2
- Issue
- 3
- Published
- Pages
- 97–168
- Articles
- 9
- Sections
- 3
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
Editorial
- Forum Article
Nonviral gene delivery system
Ningning Yang
pp. 97–98 · DOI: 10.4103/2230-973X.104388 · Published
Gene therapy has been investigated a lot in both basic research and clinical trials.[1] The first antisense oligodeoxyribonucleotide (ODN) drug, Vitravene (Fomivirsen), was approved by the United States Food and Drug Adm…
Review Article
- Review
A comprehensive study on regulatory requirements for development and filing of generic drugs globally
Shweta Handoo, Vandana Arora, Deepak Khera, Prafulla Kumar Nandi, Susanta Kumar Sahu
pp. 99–105 · DOI: 10.4103/2230-973X.104392 · Published
The regulatory requirements of various countries of the world vary from each other. Therefore, it is challenging for the companies to develop a single drug which can be simultaneously submitted in all the countries for a…
- Review
Treatment modalities and evaluation models for periodontitis
Mohammad Tariq, Zeenat Iqbal, Javed Ali, Sanjula Baboota, Sushama Talegaonkar, Zulfiqar Ahmad, Jasjeet K Sahni
pp. 106–122 · DOI: 10.4103/2230-973X.104394 · Published
Periodontitis is the most common localized dental inflammatory disease related with several pathological conditions like inflammation of gums (gingivitis), degeneration of periodontal ligament, dental cementum and alveol…
Original Research Article
- Article
Directly compressible medicated chewing gum formulation for quick relief from common cold
Shivang A Chaudhary, Aliasgar F Shahiwala
pp. 123–133 · DOI: 10.4103/2230-973X.104395 · Published
Introduction: Common cold is the most frequently recurring disease in the world and is a leading cause of doctor visits and missed days from school and work. Cold reliever medicated chewing gum (MCG) will be a definitive…
- Article
Preparation and characterization of superporous hydrogel based on different polymers
Hitesh V Chavda, Rupal D Patel, Ishan P Modhia, Chhagan N Patel
pp. 134–139 · DOI: 10.4103/2230-973X.104396 · Published
Introduction: Superporous hydrogel (SPH) swells very rapidly in a shorter period of time to an equilibrium size and contains highly porous structure.Aim:The synthesis of SPH of poly (acrylamide-co-acrylic acid) and its c…
- Article
Formulation and evaluation of microemulsion-based hydrogel for topical delivery
Vidya Sabale, Sejal Vora
pp. 140–149 · DOI: 10.4103/2230-973X.104397 · Published
Background: The purpose of this study was to develop microemulsion-based hydrogel formulation for topical delivery of bifonazole with an objective to increase the solubility and skin permeability of the drug. Materials a…
- Article
Formulation and characterization of ketoprofen liquisolid compacts by Box-Behnken design
G Vijayaranga Vittal, R Deveswaran, S Bharath, BV Basavaraj, V Madhavan
pp. 150–156 · DOI: 10.4103/2230-973X.104398 · Published
Introduction: Liquisolid technique is used in delivery of lipophilic and poorly water soluble drugs through oral route. It involves dissolving water insoluble drugs in nonvolatile solvents and converting into acceptably …
- Article
Development and evaluation of chitosan based oral controlled matrix tablets of losartan potassium
Tallapaneni Vishnuvardhan Rao, GB Kiran Kumar, Mohammed Gulzar Ahmed, Vedamurthy Joshi
pp. 157–161 · DOI: 10.4103/2230-973X.104399 · Published
Aim and Background:The novelty of the present study was to control the release profile of matrix tablets of losartan potassium prepared by using different concentrations of chitosan and trisodium citrate as cross-linking…
- Article
Formulation and evaluation of sublingual tablets containing Sumatriptan succinate
Shailesh T Prajapati, Parth B Patel, Chhagan N Patel
pp. 162–168 · DOI: 10.4103/2230-973X.104400 · Published
Objective:Sumatriptan succinate is a selective 5-hydroxytryptamine-1 receptor agonist effective in the acute treatment of migraine headaches, having low bioavailability of about 15% orally due to first-pass metabolism. T…