International Journal of Pharmaceutical Investigation
Volume 2, Issue 4
· pp. 169–217 · 8 articles
- Volume
- 2
- Issue
- 4
- Published
- Pages
- 169–217
- Articles
- 8
- Sections
- 3
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
Review Article
- Review
Formulation strategies for drug delivery of tacrolimus: An overview
Pranav Patel, Hitesh Patel, Shital Panchal, Tejal Mehta
pp. 169–175 · DOI: 10.4103/2230-973X.106981 · Published
Tacrolimus (FK 506) is a potent macrolide lactone immunosuppressive agent used for prophylaxis of organ rejection after transplantation and graft‑versus‑host disease after bone marrow transplantation in patients. Moreove…
Original Research Article
- Article
Formulation and optimisation of raft‑forming chewable tablets containing H2 antagonist
Shailesh T Prajapati, Anant P Mehta, Ishan P Modhia, Chhagan N Patel
pp. 176–182 · DOI: 10.4103/2230-973X.106988 · Published
Purpose: The purpose of this research work was to formulate raft‑forming chewable tablets of H2 antagonist (Famotidine) using a raft‑forming agent along with an antacid‑ and gas‑generating agent.Materials and Methods: Ta…
- Article
Formulation and evaluation of carvedilol melt‑in‑mouth tablet using mucoadhesive polymer and PEG‑6‑stearate as hydrophilic waxy binder
Amish Ashvinkumar Dangi, Prakash Bhikhabhai Zalodiya
pp. 183–188 · DOI: 10.4103/2230-973X.106989 · Published
Purpose: The demand for melt-in-mouth tablets (MMTs) has been rapidly growing during the last decade, especially for the elderly and children who have swallowing difficulties, to avoid first-pass metabolism and quick dru…
- Article
Influence of excipients and processing conditions on the development of agglomerates of racecadotril by crystallo‑co‑agglomeration
Kevin Garala, Jaydeep Patel, Anjali Patel, Mihir Raval, Abhay Dharamsi
pp. 189–200 · DOI: 10.4103/2230-973X.106996 · Published
Purpose:The purpose of the present investigation was to improve the flow and mechanical properties of racecadotril by a crystallo‑co‑agglomeration (CCA) technique. Direct tableting is a requirement of pharmaceutical indu…
- Article
Formulation and evaluation of Ketoconazole niosomal gel drug delivery system
SB Shirsand, MS Para, D Nagendrakumar, KM Kanani, D Keerthy
pp. 201–207 · DOI: 10.4103/2230-973X.107002 · Published
Purpose:Niosomes play an increasingly important role in drug delivery as they can reduce toxicity and modify pharmacokinetic and bio-availability. Topically applied niosomes can increase the residence time of drugs in th…
- Article
Development of time controlled chronomodulated tablet with swelling and rupturable layers: Optimization of factors influencing lag‑time and drug release
Mayur Desai, Rishad R Jivani, Laxman D Patel, Noordin P Jivani, Bhavin Sonagara
pp. 208–212 · DOI: 10.4103/2230-973X.107005 · Published
Introduction:A tablet system consisting of cores coated with two layers of swelling and rupturable coatings was prepared and evaluated as time controlled chronomodulated tablet. Materials and Methods:Cores containing Mon…
- Article
Evaluation of metronidazole nanofibers in patients with chronic periodontitis: A clinical study
Thakur Prasad Chaturvedi, Ruchi Srivastava, Anand Kumar Srivastava, Varun Gupta, Pushpendra Kumar Verma
pp. 213–217 · DOI: 10.4103/2230-973X.107007 · Published
Aim:Prevention of periodontal disease progression is the primary goal of periodontal therapy. When conventional therapy is found to be inadequate in achieving periodontal health in chronic periodontitis, local antimicrob…
Letter to Editor
- Article
Delivery of nutraceuticals using nanotechnology
Viroj Wiwanitkit
pp. 218 · DOI: 10.4103/2230-973X.107008 · Published
The editorial on delivery of nutraceuticals using nanotechnology is very interesting.[1] As noted, successful formulation of new nanosubstance is the hope. However, the effectiveness and safety is still the consideration…