International Journal of Pharmaceutical Investigation
Volume 3, Issue 1
1 January 2013 · pp. 1–65 · 8 articles
- Volume
- 3
- Issue
- 1
- Published
- 1 January 2013
- Pages
- 1–65
- Articles
- 8
- Sections
- 2
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
Review Article
- Review
Novel gene delivery systems
Steffy B Manjila, Jomon N Baby, Elambilan N Bijin, Icey Constantine, Kannissery Pramod, Janardhanan Valsalakumari
pp. 1–7 · DOI: · Published 1 January 2013
Gene therapy is an emerging field in medical and pharmaceutical sciences because of its potential in treating chronic diseases like cancer, viral infections, myocardial infarctions, and genetic disorders. Application of …
- Review
Exploring targeted pulmonary delivery for treatment of lung cancer
Amit Goel, Sanjula Baboota, Jasjeet K Sahni, Javed Ali
pp. 8–14 · DOI: 10.4103/2230-973X.108959 · Published 1 January 2013
Lung cancer is the most malignant cancer today. The treatment of lung cancer continues to be a challenge for oncologists. The direct delivery of chemotherapeutic agents to the lungs could represent a novel therapeutic ap…
Original Research Article
- Article
Quality risk management of top spray fluidized bed process for antihypertensive drug formulation with control strategy engendered by Box‑behnken experimental design space
Amit Mukharya, Paresh U Patel, Dinesh Shenoy, Shivang Chaudhary
pp. 15–28 · DOI: 10.4103/2230-973X.108960 · Published 1 January 2013
Introduction: Lacidipine (LCDP) is a very low soluble and highly biovariable calcium channel blocker used in the treatment of hypertension. To increase its apparent solubility and to reduce its biovariability, solid disp…
- Article
Formulation and evaluation of periodontal in situ gel
Kevin Garala, Parth Joshi, Malay Shah, A Ramkishan, Jaydeep Patel
pp. 29–41 · DOI: 10.4103/2230-973X.108961 · Published 1 January 2013
Background: The present study was aimed to develop and optimize in situ gel for the treatment of periodontal disease. Materials and Methods: Temperature‑sensitive in situ gel containing 0.1% w/v Chlorhexidine hydrochlori…
- Article
Fabrication and in vitro evaluation of mucoadhesive ondansetron hydrochloride beads for the management of emesis in chemotherapy
Raj Kaur Malik, Prashant Malik, Neha Gulati, Upendra Nagaich
pp. 42–46 · DOI: 10.4103/2230-973X.108962 · Published 1 January 2013
Background: Mucoadhesive beads were fabricated and evaluated for controlled release of an antiemetic drug ‘Ondansetron Hydrochloride’. Ondansetron hydrochloride is a serotonin 5‑HT3 receptor antagonist mainly used for th…
- Article
Formulation and evaluation of buccal film of Ivabradine hydrochloride for the treatment of stable angina pectoris
Mohasin Lodhi, Akhilesh Dubey, Reema Narayan, Prabhakara Prabhu, Sneh Priya
pp. 47–53 · DOI: 10.4103/2230-973X.108963 · Published 1 January 2013
Background: Ivabradine hydrochloride is an anti‑anginal drug with a biological half‑life of about 2 h, and repeated daily administration is needed to maintain effective plasma level. Present investigation of buccal films…
- Article
Skin decontamination cream for radiological contaminants: Formulation development and evaluation
Abdul Wadood Khan, Sabna Kotta, Sudha Rana, Shahid Husain Ansari, Rakesh Kumar Sharma, Javed Ali
pp. 54–59 · DOI: 10.4103/2230-973X.108964 · Published 1 January 2013
Background:Increased use of the radioactive materials in the field of research, medical, nuclear power plant, and industry has increased the risk of accidental exposure. Intentional use of the radioisotopes by terrorist …
- Article
Comparative release profile of sustained release matrix tablets of verapamil HCl
Vikas Mathur, Kalpana Nagpal, Shailendra Kumar Singh, Dina Nath Mishra
pp. 60–65 · DOI: 10.4103/2230-973X.108965 · Published 1 January 2013
Introduction: Verapamil hydrochloride (VH) is a calcium channel blocking agent used in the treatment of hypertension, cardiac arrhythmia and angina pectoris. The short half‑life and high frequency of administration of VH…