International Journal of Pharmaceutical Investigation
Volume 6, Issue 4
· pp. 181–246 · 8 articles
- Volume
- 6
- Issue
- 4
- Published
- Pages
- 181–246
- Articles
- 8
- Sections
- 2
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
Original Research Article
- Article
Bioadhesive floating microsponges of cinnarizine as novel gastroretentive delivery: Capmul GMO bioadhesive coating versus acconon MC 8‑2 EP/NF with intrinsic bioadhesive property
Smita Raghuvanshi, Kamla Pathak
pp. 181–193 · DOI: 10.4103/2230-973X.195923 · Published
Introduction: The study was aimed at the development of low-density gastroretentive bioadhesive microsponges of cinnarizine by two-pronged approach (i) coating with bioadhesive material and (ii) exploration of acconon MC…
- Article
Mechanistic insights into acyclovir‑polyethylene glycol 20000 binary dispersions
Krishnamoorthy Venkateskumar, Subramani Parasuraman, Raju Gunasunderi, Krishnan Sureshkumar, M. Muralidhar Nayak, Syed Adnan Ali Shah, Khoo Kassen, Heng Wei Kai
pp. 194–200 · DOI: 10.4103/2230-973X.195925 · Published
Objective: The objective of this study is to provide a mechanistic insight into solubility enhancement and dissolution of acyclovir (ACY) by polyethylene glycol20000 (PEG20000). Materials and Methods:Solid dispersions wi…
- Article
Formulation development and evaluation of zolmitriptan oral soluble films using 22 factorial designs
Poluri Koteswari, G. Puja Sravanthi, M. Mounika, S. K. Mohammed Rafi, K. Nirosha
pp. 201–206 · DOI: 10.4103/2230-973X.195927 · Published
Objective: The present investigation involves the development of zolmitriptan oral soluble film (OSF) formulations and optimization with quality by design (QBD) using natural polymers and evaluation. Materials and Method…
- Article
Formulation and development of plasma volume expander using natural and modified starch from Solanum tuberosum
Nilima A. Thombre, Ajit V. Vishwakarma, Trupti S. Jadhav, Sanjay J. Kshirsagar
pp. 207–217 · DOI: 10.4103/2230-973X.195930 · Published
Background: To formulation and development of plasma volume expander (PVE) by using natural and modified starch from Solanum tuberosum. The function of blood circulation is to provide the needs of the body tissues and to…
- Article
Enhanced bioavailability of danazol nanosuspensions by wet milling and high‑pressure homogenization
Naveen Kanthamneni, Satyanarayana Valiveti, Mita Patel, Heather Xia, Yin‑Chao Tseng
pp. 218–224 · DOI: 10.4103/2230-973X.195931 · Published
Introduction: The majority of drugs obtained through synthesis and development show poor aqueous solubility and dissolution velocity, resulting in reduced bioavailability of drugs. Most of these problems arise from formu…
- Article
Sodium dithionite‑enhanced quality of radix scutellariae through modification of secondary metabolism
Guo Huimin, Fu Xiaoying, Du Hongwei, Cong Wei, Meng Xiangcai
pp. 225–230 · DOI: 10.4103/2230-973X.195932 · Published
Introduction: The quality of radix scutellariae is particularly associated with environmental stresses, but detailed mechanisms remained unclear. Plant under unfavorable situation generates redundant reactive oxygen spec…
- Article
Synergetic effects of silver and gold nanoparticles in the presence of radiofrequency radiation on human kidney cells
Jafar Fattahi‑asl, Mojtaba Karbalaee, Masoud Sanatizadeh, Payam Amini
pp. 231–237 · DOI: 10.4103/2230-973X.195933 · Published
Objective: The aim of this study was to compare the effects of radiofrequency radiation (RF) in synergism with gold (Au) and silver (Ag) nanoparticles (NPs) on the survival fraction of human normal kidney (HNK) and human…
Original Original Research Article
- Article
Development, evaluation, and influence of formulation and process variables on in vitro performance of oral elementary osmotic device of atenolol
N. Arjun, D. Narendar, K. Sunitha, K. Harika, B. Nagaraj
pp. 238–246 · DOI: 10.4103/2230-973X.195951 · Published
Purpose:Osmotic devices are the most promising strategy-based systems for controlled drug delivery. By optimizing formulation and processing parameters, possible to develop osmotic systems to deliver drugs at predetermin…