Late-Onset Clozapine-Induced Agranulocytosis in a Young Woman with Paranoid Schizophrenia
Anuhya Vinayaka1, Shubha Sheshadri2, Sharath P. Madhyastha2★, Ganesh V. Shetty2, Charan Thej Reddy2★ Corresponding author
- 1Department of Pharmacology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
- 2Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
CORRESPONDENCE
Sharath P. Madhyastha
Assistant Professor, Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
Received: 07-06-2020; Revised: 23-09-2020; Accepted: 21-10-2020.
Volume 11, Issue 4 · pp. 140–141 · PUBLISHED 14 May 2021 · DOI: 10.4103/jpp.JPP_29_20
ABSTRACT
Treatment of schizophrenia has taken so many turns, and adverse effects of the drugs still continue to remain as a hurdle in the management. Clozapine is considered to be the better promising drug in the treatment of paranoid schizophrenia with minimal side effects. Clozapine-induced agranulocytosis is one adverse event that troubles clinicians, and it requires a vigilant eye to look for the signs. In the present study, the authors discuss a case which has developed agranulocytosis in the later stages of clozapine treatment.
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Vinayaka, A., Sheshadri, S., Madhyastha, S. P., Shetty, G. V., & Reddy, C. T. (2021). Late-Onset Clozapine-Induced Agranulocytosis in a Young Woman with Paranoid Schizophrenia. Journal of Pharmacology and Pharmacotherapeutics, 11(4), 140–141. https://doi.org/10.4103/jpp.JPP_29_20