Volume 17, Issue 1

Mohammad Akbar Hossain

pp. 5–16 · DOI: 10.1177/0976500X251321295 · 2026

Background: Varicocelectomy is one of the main complications that, if left untreated, results in male infertility. Various approaches have been adopted to manage it, but there is a variation in the consensus. Objectives:…

Annisa Fatharani, Ali Alsayegh

pp. 17–26 · DOI: 10.1177/0976500X251321885 · 2026

Background: Pharmacogenomics aims to optimise drug therapy based on genetic makeup, but traditional clinical trial design faces challenges with complexity, cost and data integration. Objectives: This study explores integ…

Lim Chin Hung, Subramani Parasuraman, Sam Aaseer Thamby

pp. 27–36 · DOI: 10.1177/0976500X251329142 · 2026

Background: In this modern era, the practice of online learning and various academic assignments necessitate the use of digital device among university students. With prolonged and inappropriate use, they are prone to th…

Fahad Adel Balghonaim, Kumarswamy Kunigal Chandru, Madhu Bommanahalli Krishnegowda, Nimbagal Raghavendra Naveen, Prakash Goudanavar, Vedamurthy Joshi, Girish Meravanige, Predeepkumar Narayanappa Shiroorkar, Nagaraja Sreeharsha, Krishna Swaroop

pp. 37–52 · DOI: 10.1177/0976500X251327444 · 2026

Background: Pulmonary arterial hypertension is controlled by the dual endothelin receptor antagonist bosentan monohydrate. Recent advances in microneedle technology offer controlled, prolonged drug release. Objectives: T…

Reem Raheem, Esha Junais, Rena Yusuf Rassal, Suresh Kumar Srinivasamurthy, Mohamedanas Mohamedfaruk Patni

pp. 53–61 · DOI: 10.1177/0976500X251336868 · 2026

Background: Improving patient safety is vital, with medication errors posing serious risks. Understanding health professional students’ views on errors is crucial for fostering vigilant patient safety practices among fut…

Khalid Alshaghdali, Raja Rezgui, Talal Alharazi, Tolgahan Acar, Gamal Mohamed Elawad Ahmed, Emad Abboh Abdallah Abboh, Kamal Yassin, Amre Nasr, Mohd Saeed, Amir Saeed

pp. 62–68 · DOI: 10.1177/0976500X251336865 · 2026

Background/Objectives: Complications associated with diabetes are predominantly influenced by the polyol pathway, in which aldose reductase 2 (ALR2) is instrumental in converting surplus glucose into sorbitol, resulting …

Muhammed Hassan Nasr, Noordin Othman, Bassam Abdulrasool Hassan, Mahmathi Karuppannan, Noorizan Binti Abdulaziz, Mohammed Ahmed Alsarani, Shalam Mohamed Hussain

pp. 69–76 · DOI: 10.1177/0976500X251339561 · 2026

Background: Vitamin D deficiency poses significant health risks globally, impacting bone health and immune function. In Saudi Arabia, where environmental and lifestyle factors limit sun exposure, vitamin D deficiency is …

Sara Seifeldin, Nujud Almuzaini, Mohd Saeed, Rania Abdeen Hussain Abdalla, Md Jahoor Alam, Khalid Alshaghdali, Amir Saeed, Talal Alharazi, Elgeli Yousif

pp. 77–83 · DOI: 10.1177/0976500X251339865 · 2026

Background/Objectives: Diabetes and cancer are common diseases, and epidemiologic evidence suggests that people with diabetes are at significantly higher risk for many forms of cancer. Both these diseases are among the h…

Ayisha Thacharupadikkal Thazhath, Rithwij Kakkanattu, Muhasina Razak Valatheyil, Aneena Joju, Dilip Chandrasekhar, Vipin Kalathil

pp. 84–93 · DOI: 10.1177/0976500X251321891 · 2026

Background: After the restoration of COVID-19 lockdowns and the relaxation of general public health restrictions, an upswing in the incidence of respiratory diseases was observed. Respiratory illnesses have been soaring …

Altaf O. Mulani, Kazi Kutubuddin Sayyad Liyakat, Nilima S. Warade, Alaknanda Patil, Mahesh T. Kolte, Kishor Kinage, Manish Rana, Shweta Sadanand Salunkhe, Vaishali Satish Jadhav, Megha Nagrale

pp. 94–100 · DOI: 10.1177/0976500X251324735 · 2026

Background: The Internet of Things (IoT) and wireless sensor networks (WSNs) are now being explored and used in various sectors, thanks to recent technological advancements. Objectives: The healthcare sector is one of th…

Patrick A. Kalona, Uma Sundaresan, Chellappandian M., Ariharasivakumar G.

pp. 101–110 · DOI: 10.1177/0976500X251319595 · 2026

Background: Rheumatoid arthritis (RA) affects nearly 4% of the world’s population, along with an increasing rate of new cases. Objectives: The current work was focused on investigating the anti-arthritic efficacy of the …

Gowri Venugopal, Kumaravelu Punnagai, Sukumar Ramya

pp. 111–116 · DOI: 10.1177/0976500X251319832 · 2026

Background: Cancer has become the second leading cause of death among the Indian population. Objectives: The purpose of the research was to elucidate and compare the suppressive impact on cell proliferation of metformin,…

Zeenath Unnissa, Umair Wahedi, Zeba Fatima, Mohammed Mudassir, Parthasaradhi Sarvepally

pp. 117–126 · DOI: 10.1177/0976500X251332091 · 2026

Background: Chronic kidney disease (CKD) is a condition that deteriorates over time and causes the loss of nephrons, leading to impaired kidney function and finally bringing on end-stage renal disease (ESRD). As the worl…

Rahul Sudhakar Gawande, Anil Meghrajji Pethe

pp. 127–134 · DOI: 10.1177/0976500X251334168 · 2026

Background: Lifitegrast, a lymphocyte function-associated antigen-1 antagonist, was found to be useful in the treatment of psoriasis. Objectives: The study aimed to evaluate semisolid formulations of lifitegrast for thei…

Vanita Dnyandev Jadhav, Lalit Vasantrao Patil

pp. 135–144 · DOI: 10.1177/0976500X251336602 · 2026

Background: Automatic lung segmentation is a crucial initial step in computer-aided lung computed tomography (CT) diagnosis. However, existing methods struggle to achieve accurate segmentation in the presence of dense ab…

Rajdeep Chakraborty, Pallavi Khodlan, Arthur Chien, Chao Shen, Thiri Zaw, Matthew Fitzhenry, Ardeshir Amirkhani, Fei Liu

pp. 145–147 · DOI: 10.1177/0976500X251321892 · 2026

Epidermal growth factor receptor (EGFR) plays an active role during the progression of oral squamous cell carcinoma (OSCC). OSCC is the most common head and neck cancer. Cetuximab, which is an inhibitor of EGFR, was appr…

Reeya Gamne, Sadhana Misar Wajpeyi, Sonia Mandal, Mayank Rai

pp. 148–156 · DOI: 10.1177/0976500X251319833 · 2026

Background: Lumbar canal stenosis (LCS) is a degenerative spinal condition causing narrowing of the spinal canal, leading to nerve compression. Symptoms include pain, stiffness, tingling, numbness, and difficulty walking…