Volume 17, Issue 2

Chiamaka Onyekwuluje, Nokwanda Ngcobo, Ntethelelo Sibiya

pp. 161–173 · DOI: 10.1177/0976500X251365078 · 2026

Background: The brain, through the sensory action of neurons situated in the hypothalamus and brainstem, plays a pivotal role in the homeostatic regulation of glucose metabolism. The brain senses changes in nutrients and…

Syam Mohan, Nizar A. Khamjan, Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Jobran M. Moshi, Abrar Fahad Alshahrani, Jeraiby A. Mohammed, Saeed Alshahrani, Khaled A. Sahli, Hatem Ahmed Salem Alqhtani, Muhammad H. Sultan, Marwa Qadri, Ali Ibrahim Ali Ashgar, Abdullah Farasani, Hussain Ali I. Shobaili, Abdualmagid Mohammed Tobaiqi, Tariq Idris Somily

pp. 174–190 · DOI: 10.1177/0976500X251361201 · 2026

Background: Exosomes, key mediators of intercellular communication, transport functional biomolecules, making them promising tools for diagnostics and therapeutics across various human diseases. Objectives: To systematic…

Jumaila Kooriparambil, Vijaya Chitra Arumugam, Vajid Nettoor Veettil, Shamla Alikadavath

pp. 191–198 · DOI: 10.1177/0976500X251347425 · 2026

Purpose/Background: This study aimed to isolate, purify, and characterize a novel bacteriocin produced by Lactobacillus casei strain GO3, isolated from goat milk. Bacteriocins are promising natural antimicrobial agents w…

Jyoti Sharma, Himani Deswal, Jyoti Kaushal, Suneel Rohilla

pp. 199–205 · DOI: 10.1177/0976500X251336881 · 2026

Background: Competency-based medical education (CBME) is an approach that ensures that the focus of teaching, learning, and assessment is on real-life medical practice. There is a radical shift in the teaching, learning,…

Vignesh Mohan, Anil M. Pethe

pp. 206–213 · DOI: 10.1177/0976500X251336879 · 2026

Background: Ubrogepant is a successful drug used for the therapy of migraine. Objectives: The objective of this work was to formulate a novel nanoparticle-based therapy using ubrogepant for optimum therapeutic efficacy b…

and Vidya Gowdappa Doddawad

pp. 214–219 · DOI: 10.1177/0976500X251371105 · 2026

Background: Drug–drug interactions (DDIs) are a significant concern among cardiac inpatients, potentially impacting therapeutic outcomes and patient safety. Early identification and management of potential DDIs are cruci…

Danisha Pattani, Dilip Chandrasekhar

pp. 220–230 · DOI: 10.1177/0976500X251345885 · 2026

Background: Prescriptions are medication plans communicated between prescribers and pharmacists for patients. An ideal prescription must be rational, evidence-based, complete, and clear, and enhance the therapeutic outco…

Kashish Wilson, Chander Parkash Dora, Garima, Bharat Bhushan, Anjali Bhardwaj, Pramila Chaubey, Sumeet Gupta

pp. 231–243 · DOI: 10.1177/0976500X251347400 · 2026

Background: Several therapies are available for psoriasis, including oral, parenteral, and phototherapy. However, these treatments present various drawbacks, like mucosal ulceration, stomatitis, bioavailability issues, p…

Vignesh Mohan, Anil Meghrajji Pethe

pp. 244–252 · DOI: 10.1177/0976500X251347402 · 2026

Background: Ubrogepant is a first-generation gepant-class drug approved for the oral treatment of migraine. Objectives: This work aimed at developing an intranasal gel consisting of ubrogepant nanoparticles (NPs), with t…

Chompoonuch Werawattanachai, Pattaramart Hadee, Jitapa Sornsoongneon, Tuanthon Boonlue

pp. 253–259 · DOI: 10.1177/0976500X251390085 · 2026

Background: Selective serotonin reuptake inhibitors (SSRIs), including fluoxetine and sertraline, are widely prescribed for depression due to their favorable safety profiles compared to older anti-depressants. However, t…

Vanita Dnyandev Jadhav, Lalit Vasantrao Patil

pp. 260–270 · DOI: 10.1177/0976500X251353660 · 2026

Aim/Background: Accurate staging of lung cancer is critical for treatment planning and prognosis. Traditional methods typically rely on binary classification and manual analysis of computed tomography (CT) scans, limitin…

Abdullah Farasani

pp. 271–278 · DOI: 10.1177/0976500X251355425 · 2026

Background: Leopoldia comosa is a traditional Mediterranean plant with medicinal and nutritional value. Despite its long history of use, scientific exploration remains limited. Objectives: This study aimed to provide the…

Yu Hao Cui, JinYi Zhu

pp. 279–283 · DOI: 10.1177/0976500X251383596 · 2026

Background: Intraoperative hypothermia is a common complication in elderly patients undergoing joint replacement surgery that can lead to adverse outcomes. Objectives: This study aimed to analyze the pertinent risk facto…

Sneha Chacko, Gaurang Shah, Tushar Patel, Aviral R. Tripathi, Indermeet Singh Anand, Chirag Shah

pp. 284–291 · DOI: 10.1177/0976500X251350484 · 2026

Background: Chronic respiratory diseases (CRDs) significantly impact patients’ quality-of-life (QoL), necessitating effective interventions for symptom management and functional improvement. Pulmonary rehabilitation (PR)…

Sangeetha Subramanian, Kavitha Sanjeev, Prakash PSG, Devapriya Appukuttan, Jasmine Crena, Santo Grace Umesh

pp. 292–298 · DOI: 10.1177/0976500X251355377 · 2026

Background: Periodontitis, an inflammatory disease, is caused by oral biofilm, and several risk factors propagate it. Smoking is a significant risk factor that increases the severity of the disease. Arylamine N-acetyltra…

Ahmed S. Alamer

pp. 299–307 · DOI: 10.1177/0976500X251357060 · 2026

Background: Premature ejaculation (PE) is one of the most common sexual dysfunctions affecting men. Among the available treatments, selective serotonin reuptake inhibitors (SSRIs) have gained considerable attention. Obje…

Dharini Boopathi, Suganya P, Arunkumar Subramanian, Rajamohamed H

pp. 308–314 · DOI: 10.1177/0976500X251347404 · 2026

Background: Acneiform eruption is a dermatological condition resembling acne vulgaris, with a similar clinical presentation that is often difficult to differentiate. Several medications like corticosteroids, anti-convuls…