Volume 3, Issue 4

Amar Jesani

pp. 297–299 · DOI: 10.4103/0976-500X.103684 · 2012

On May 8, 2012, the Department Related Parliamentary Standing Committee (henceforth Committee) presented to the Parliament its 59th report on the functioning of Central Drugs Standard Control Organization (CDSCO) in the …

Jaykaran Charan, Jagdish P. Goyal, Deepak Saxena, Preeti Yadav

pp. 300–303 · DOI: 10.4103/0976-500X.103685 · 2012

Objectives: To explore the effect of vitamin D supplementation in prevention of respiratory tract infections on the basis of published clinical trials. Materials and Methods: Clinical trials were searched from various el…

Hasime Qorraj-Bytyqi, Rexhep Hoxha, Shaip Krasniqi, Elton Bahtiri, Valon Kransiqi

pp. 304–307 · DOI: 10.4103/0976-500X.103686 · 2012

Objective: To investigate the prevalence of the major drug interactions in children and verify the rate and profile of drug interactions in hospitalized pediatric patients. Materials and Methods: A retrospective study wa…

Maulik S. Doshi, Prakruti P. Patel, Samidh P. Shah, Ram K Dikshit

pp. 308–313 · DOI: 10.4103/0976-500X.103687 · 2012

Objective: To detect incidence of adverse drug reactions (ADRs) in hospitalized patients and to assess their causality, seriousness, preventability, and the possible economic impact. Materials and Methods: This was a pro…

Dhanani Jatin V., Ganguly B. P., Chauhan L. N.

pp. 314–319 · DOI: 10.4103/0976-500X.103688 · 2012

Objective: To compare the efficacy and safety with a fixed dose of two parenteral iron preparations, iron sucrose complex and iron sorbitol citric acid as per the current practice. Materials and Methods: A prospective ra…

Arijit Ghosh, Utpal Jana, Ajoy Khaowas, Saumik Das, Ananya Mandal, Nina Das

pp. 320–324 · DOI: 10.4103/0976-500X.103689 · 2012

Objective: To compare the effectiveness and safety of cefpodoxime and ciprofloxacin for the treatment of mild to moderate cases of acute exacerbation of chronic suppurative otitis media (AECSOM). Materials and Methods: A…

Purav Mody, Tamoghona Biswas, Jaykaran Charan, Deval Parikh

pp. 325–326 · DOI: 10.4103/0976-500X.103690 · 2012

Every year, a large number of clinical trials studying pharmacological agents are published in the Indian medical/ dental Literature. Data on potential adverse drug reactions (ADRs) occurring during such studies needs to…

S. Stephen Ambrose, P. Solairaj, A. Subramoniam

pp. 326–328 · DOI: 10.4103/0976-500X.103691 · 2012

In the absence of satisfactory treatment using conventional medicine, treatment of liver disorders remains as one of the major medical problems.[1] Numerous medicinal plants are used in local health traditions to treat l…

Faiyaz Ahmed, Kumar S., Asna Urooj, Kemparaju K.

pp. 329–330 · DOI: 10.4103/0976-500X.103692 · 2012

Blood platelet activation and aggregation play an important physiological role in the hemostasis and it is well established that many cardiovascular disorders are linked to an abnormal excessive activation of platelets. …

Raj Rajeshwari R. Patil, Pratibha S. Worlikar, Amol B. Chaudhari, Ozhukil K. Radhakrishnan, Rajendra P. Gupta, Saurabh Puri

pp. 330–332 · DOI: 10.4103/0976-500X.103693 · 2012

Cataract is the leading cause of blindness with a number of risk factors such as aging, genetic, steroids, nitric oxide, diabetes, ultraviolet radiation and smoking. An increased incidence of cataract is associated with …

Fatma Sarı Doğan, Özge Ecmel Onur, Arzu Denizbaşı Altınok, Özlem Güneysel

pp. 333–335 · DOI: 10.4103/0976-500X.103694 · 2011

Insulin glargine is a long acting novel recombinant human insulin analogue indicated to improve glycemic control, in adults and children with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus. The time…

Manish J. Barvaliya, Mahendra K. Patel, Tejas K. Patel, C. B. Tripathi

pp. 336–338 · DOI: 10.4103/0976-500X.103695 · 2012

A 12-year-male child developed toxic epidermal necrolysis (TEN) probably due to lamotrigine. The patient was on antiepileptic therapy (sodium valproate and clonazepam) since 6–7 months, and lamotrigine was added in the r…

Shilpashree H. S., Shriprasad Sarapur

pp. 339–341 · DOI: 10.4103/0976-500X.103696 · 2012

Ciprofloxacin is one of the most commonly used antibacterial agents with relatively few side effects. Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0.6%. One of the side effects of c…

Sasmita Biswal

pp. 342–344 · DOI: 10.4103/0976-500X.103697 · 2012

We present a case of complete heart block (CHB) in a 58‑year‑old female patient with acute myeloid leukemia (AML) with no past history of cardiac disease, who received caspofungin in the treatment of disseminated fungal …

Suneet K. Upadhyaya, Archana Sharma, Deependra K. Rai, Vijay Thawani

pp. 345–347 · DOI: 10.4103/0976-500X.103698 · 2012

This is the first case report depicting masking of symptoms of intestinal tuberculosis by anabolic androgenic steroids (AAS) causing delay in diagnosis which lead to a major surgery. Negative tuberculosis skin test (TST)…

Shivaji P. Gawade

pp. 348–348 · DOI: 10.4103/0976-500X.103699 · 2012

Writhing test is a chemical method used to induce pain of peripheral origin by injection of irritant principles like phenylquinone, acetic acid in mice. Analgesic activity of the test compound is inferred from decrease i…

2012;345:e4260. 2012;345:e4260.

pp. 349–350 · DOI: 10.4103/0976-500X.103700 · 2012

It has been roughly estimated that it would take about 4 h for injured soldiers to receive a blood transfusion at a hospital. Researchers at Massachusetts General Hospital wondered whether histone deacetylase (HDAC) inhi…

Sivagnanam G

pp. 350–350 · 2012

Pendrin is expressed on the cells of distal convoluted tubule and the collecting duct. It is involved in Cl-/HCO3- exchange (mediates HCO3- secretion and Cl- absorption) and has been demonstrated to play an important rol…

S. Parasuraman

pp. 351–2 · DOI: 10.4103/0976-500X.103704 · 2012

Research Collaborators for structural Bioinformatics Protein Data Bank (RCBS PDB) began in 1970’s by group of the young crystallographers, including Edgar Meyer, Gerson Coheon and Helen M Berman.[1] The project was initi…

Suruchi Aditya, Aditya Rattan

pp. 353–355 · DOI: 10.4103/0976-500X.103705 · 2012

Heart failure in India is a growing epidemic. Around 30 to 40% of patients die from heart failure within one year of receiving the diagnosis. Currently available inotropes have not only failed to show consistent results …