Volume 5, Issue 2

Gitanjali Batmanabane

pp. 81–2 · DOI: 10.4103/0976-500X.130040 · 2014

Jissa Maria Cyriac, Emmanuel James

pp. 83–87 · DOI: 10.4103/0976-500X.130042 · 2014

Majority of the patients admitted to a hospital with severe infections are initially started with intravenous medications. Short intravenous course of therapy for 2-3 days followed by oral medications for the remainder o…

Sandeep Kumar Gupta, Roopa Prasad Nayak

pp. 88–92 · DOI: 10.4103/0976-500X.130046 · 2014

Off-label prescribing of medicines is prevalent worldwide because it gives freedom to physicians to apply new therapeutic options based on the latest evidence. Although physicians may lawfully prescribe approved drugs fo…

Mathummal Cherumanalil Jeeja, Thayyil Jayakrishnan, Puthiya Veettil Narayanan, Mathur Sreedharan Vinod Kumar, Thayyil Thejus, Vadakay Purayil Anilakumari

pp. 93–94 · DOI: 10.4103/0976-500X.130048 · 2014

Objectives: To assess the level of homocysteine (tHcy) in children taking AEDs and to study whether daily oral supplementation of folic acid for 1 month will reduce the tHcy level. Materials and Methods: This was a doubl…

Ilma Bertulyte, Sofie Schwan, Pär Hallberg

pp. 100–138 · DOI: 10.4103/0976-500X.130051 · 2014

Objectives: To identify risk factors other than genetic for severe carbamazepine-induced mucocutaneous reactions, that is, SJS, TEN, and exfoliative dermatitis (ED). Materials and Methods: We did a case‑control study usi…

Bhavik S. Shah, Shrikalp S. Deshpande

pp. 139–144 · DOI: 10.4103/0976-500X.130058 · 2014

Objectives: To evaluate and compare clinical and epidemiological characteristics, treatment strategies, and utilization of evidence-based medicine (EBM) among coronary artery disease (CAD) patients with or without diabet…

Kalpesh Jain, Mira Desai, Rajesh Solanki, Ram Kumar Dikshit

pp. 145–149 · DOI: 10.4103/0976-500X.130062 · 2014

Objective: To evaluate the treatment outcome of second line drugs used in directly observed treatment, short‑course (DOTS)‑Plus regimen under Revised National Tuberculosis Control Program (RNTCP). Materials and Methods: …

Smita Sontakke, Parag Kinge

pp. 150–151 · DOI: 10.4103/0976-500X.130066 · 2014

Informed consent (IC) is one of the most important components of ethical research in human participants. Even though it is mandatory to obtain a freely given "written IC" from each study participant before he/she is enro…

Giovanni Clemente Actis, Rinaldo Pellicano, Floriano Rosina

pp. 151–152 · DOI: 10.4103/0976-500X.130071 · 2014

The salicylate derivatives mesalamines are used to treat both ulcerative colitis and Crohn’s disease. Mesalamines are almost devoid of toxicity, apart from very low figures of nephrotoxicity as derived from large populat…

K. Manikandan, S. Raghavan

pp. 153–154 · DOI: 10.4103/0976-500X.130075 · 2014

Frusemide use in pregnancy is generally restricted to patients with cardiac decompensation. In the past, maternal administration of oral frusemide had been tried to identify non-functioning fetal kidneys by utilizing the…

Ramakant Dixit, Danish Qureshi, Sunil Mathur

pp. 155–157 · DOI: 10.4103/0976-500X.130081 · 2014

Drug-induced alopecia is a known clinical entity and mainly seen with anti-mitotic drug therapy. Alopecia during anti-tuberculosis therapy is very uncommon and previously observed with isoniazid, thiacetazone, and ethion…

Antonio De Vuono, Caterina Palleria, Francesca Scicchitano, Aida Squillace, Giovambattista De Sarro, Luca Gallelli

pp. 158–160 · DOI: 10.4103/0976-500X.130086 · 2014

Generic drugs have the same active substance, the same pharmaceutical form, the same therapeutic indications and a similar bioequivalence with the reference medicinal product (branded). Although a similar efficacy is pos…

K. M. Dhanraj, Dubashi Biswajit

pp. 161–162 · DOI: 10.4103/0976-500X.130091 · 2014

A 65 year old male diagnosed as multiple myeloma was started on bortezomib developed tumor lysis syndrome. Bortezomib induced tumor lysis is rare and suitable precautions should be considered in these patients.

Carla Carnovale, Paolo Pellegrino, Silvia Beretta, Gian Vincenzo Zuccotti, Valentina Perrone, Stefania Antoniazzi, Marco Pozzi, Emilio Clementi, Sonia Radice

pp. 163–165 · DOI: 10.4103/0976-500X.130110 · 2014

Chlorpromazine is a well‑known antipsychotic agent that binds with a variety of receptors in the central nervous system. To date, chlorpromazine has never been associated with onset of hearing disorders and tinnitus. We …

Manish J. Barvaliya, Tejas K. Patel, C. B. Tripathi

pp. 166–167 · DOI: 10.4103/0976-500X.130116 · 2014

Vishal Sehgal, Sukhminder Jit Singh Bajwa

pp. 167–169 · DOI: 10.4103/0976-500X.130147 · 2014

Medical science is witnessing a progressive revolution and evolution throughout the globe with continual improvement in diagnostics and therapeutic interventions. The literary and practical updates in medical sciences ar…

Jatinder Singh

pp. 173–4 · DOI: 10.4103/0976-500X.130155 · 2014

Dick B. S. Brashier, A. K. Sharma, Navdeep Dahiya, S. K. Singh, Anjan Khadka

pp. 175–178 · DOI: 10.4103/0976-500X.130158 · 2014

Obesity is a major co-morbidity with hypertension and diabetes mellitus. There are few drugs for treatment of obesity like orlistat and recentlty approved drug lorcaserin. Lorcaserin has serotonergic properties and acts …