Volume 5, Issue 3

Yeshwant Kurhe, Radhakrishnan Mahesh, Thangaraj Devadoss, Deepali Gupta

pp. 122–123 · DOI: 10.4103/0976-500X.136104 · 2010

Objective: To investigate the antidepressant‑like effect of N‑(benzo[d] thiazol‑2‑yl)‑3‑ ethoxyquinoxalin‑2‑carboxamide 6k, a 5‑hydroxytryptamine type 3 (5‑HT3) receptor antagonist using rodents behavioral battery tests.…

Raffaele Serra, Raffaele Grande, Gianluca Buffone, Edoardo Scarcello, Fabio Tripodi, Pierandrea Rende, Luca Gallelli, Stefano de Franciscis

pp. 193–196 · DOI: 10.4103/0976-500X.136101 · 2014

Objective: To explore the effect of sequential treatment with glucocorticoid and tumor necrosis factor‑alpha inhibitors in patients with Takayasu arteritis (TA). Materials and Methods: In five patients with TA, the effec…

Raveendran: Animal experimentation in postgraduate training Journal of Pharmacology and Pharmacotherapeutics | July-September | Vol | Issue

pp. 179–180 · DOI: 10.4103/0976-500X.136095 · 2014

The article with the headline “Medical Council of India (MCI) likely to ban animal dissection at post‑grad level too” in the Pioneer, a New Delhi based daily came as a rude shock to some of us (http://www.dailypioneer.co…

Umme Aiman, Ahmad Najmi, Rahat Ali Khan

pp. 181–185 · DOI: 10.4103/0976-500X.136097 · 2014

Statins are one of the most commonly used drugs in the world based on their potential to prevent adverse cardiovascular events. These cholesterol‑lowering drugs received a US Food and Drug Administration warning, in Febr…

Rituparna Maiti

pp. 186–192 · DOI: 10.4103/0976-500X.136098 · 2014

Toxic effects and chemoresistance are major hurdles in chemotherapy and to avoid these problems caused by traditional chemotherapeutic regimens, a new modality of drug administration called “metronomic chemotherapy” has …

Yatan Pal Singh Balhara, Raka Jain

pp. 203–205 · DOI: 10.4103/0976-500X.136106 · 2014

The findings of this study suggest that a significant proportion of individuals on OST tested positive for cannabis. It is therefore recommended to use urinalysis during OST to monitor ongoing use of cannabis. Detection …

Sandeep Grover, Siddharth Sarkar, Naresh Nebhinani, Surendra K. Mattoo, Debasish Basu

pp. 205–207 · DOI: 10.4103/0976-500X.136108 · 2014

The alcohol use disorders and sexual functioning have a complex relationship. Alcohol use has been suggested to enhance desire of sexual activity and indulgence in riskier sex. Use of alcohol has also been linked with im…

Subashini Kaliaperumal, Indu Govindaraj, Praveen Kumar Kopparapu, Shashi Ahuja

pp. 208–210 · DOI: 10.4103/0976-500X.136110 · 2014

Prostaglandin F2 alpha (PGF2α) analogues including bimatoprost are often the first line drugs used in the treatment of glaucoma. We present a case of a 62‑year‑old female patient who was started on bimatoprost in both th…

Roja Y. Ramani, Benu Panigrahy, Bandana Rath

pp. 211–213 · DOI: 10.4103/0976-500X.136112 · 2014

Aminoglycoside‑induced nephrotoxicity is not uncommon. Netilmicin being a member of gentamicin family has the advantage of being relatively free from ototoxicity and nephrotoxicity and is also prescribed for gentamicin r…

Vishal R. Tandon, Annil Mahajan, Vijay Khajuria, Zahid H. Gillani

pp. 214–216 · DOI: 10.4103/0976-500X.136113 · 2014

The risk for angioedema has been suggested lower with angiotensin receptor blockers (ARBs) than with angiotensin‑converting enzyme inhibitors (ACEIs) or aliskiren. Many isolated reports do exist, reporting angioedema wit…

Mohammad Nasiruddin, Mohd Fayazuddin, Mohammad Zahid, Syed Iftekhar

pp. 217–219 · DOI: 10.4103/0976-500X.136115 · 2014

Zoledronate is a third‑generation bisphosphonate having distinctive profile of high potency as well as prolonged duration of action. Intravenous zoledronate is the recently approved bisphosphonate for the treatment of os…

G. Sivagnanam

pp. 220–221 · DOI: 10.4103/0976-500X.136116 · 2014

pp. 220–220 · 2014

The Trial to Assess Chelation Therapy (TACT) was a study (a 10‑year, $31.6‑million study involving 1,708 participants at 134 centers) that involved an intervention of EDTA‑based infusion regimen in patients aged ≥50 year…

Alphienes Stanley Xavier, Mageshwaran Lakshmanan

pp. 222–224 · DOI: 10.4103/0976-500X.136121 · 2014

Intense search has been made in the discovery of newer anti‑TB drugs to tackle the issues such as drug resistance, HIV co‑infection and risk of drug‑drug interactions in the management of TB. Delamanid, a newer mycobacte…