Journal of Pharmacology and Pharmacotherapeutics volume 5, issue 4 cover
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Cover: Journal of Pharmacology and Pharmacotherapeutics

Journal of Pharmacology and Pharmacotherapeutics

Volume 5, Issue 4

2014 · pp. 225–284 · 18 articles

Volume
5
Issue
4
Published
2014
Pages
225–284
Articles
18
Sections
9
ISSN
Print - 0976-500X, Online - 0976-5018
Journal
JPP

In this issue

Editorial

  1. Forum Article

    Chanolean Shashindran

    pp. 225–226 · DOI: 10.4103/0976-500X.142427 · 2014

    A recent NDTV programme aired on national television created a lot of angst among those in the medical profession.[1] Here was another instance of the profession being shown in a bad light, due to the dealings of a few u…

Review Article

  1. Review

    Vishal Sehgal, Sukhminder Jit Singh Bajwa, Rinku Sehgal, John A Consalvo

    pp. 227–231 · DOI: 10.4103/0976-500X.142428 · 2014

    Canagliflozin is the first available oral inhibitor of sodium/glucose cotransporter 2 (SGLT2) in the market. At the outset it sounds excellent for the use in the elderly diabetic population, because of its minimal tenden…

Research Paper

  1. Article

    Hitesh B Vaidya, Ramesh K Goyal, Sukhinder K Cheema

    pp. 232–238 · DOI: 10.4103/0976-500X.142429 · 2014

    Objective: To investigate whether the acetylated and propionated derivatives (LMP‑09‑1 and ‑2) of swertiamarin have anti‑adipogenic effects. Materials and Methods: 3T3‑L1 pre‑adipocytes were grown in Dulbecco’s Modified …

  2. Article

    Ravi Venkatachelam Chitrapu, Pentakota Ramana Rao, Gangireddy Venkateswara Reddy

    pp. 239–244 · DOI: 10.4103/0976-500X.142430 · 2014

    Objective: To study the efficacy of oral carvedilol in acute treatment of atrial fibrillation (AF) with fast ventricular rate. Materials and Methods: In an open‑label, single‑arm trial, oral carvedilol was administered t…

Correspondence

  1. Article

    Meena Garg, Pinki Vishwakarma, Monica Sharma, Rajiv Nehra, K. K. Saxena

    pp. 245–247 · DOI: 10.4103/0976-500X.142434 · 2014

    Our study included 92 randomly selected prescriptions from allopathic registered medical practitioners between September 2011 and October 2012. These were analyzed for content and format. The number of non‑sponsored CMEs…

Research Letter

  1. Article

    Raghava Sharma, Adithi Kellarai

    pp. 248–250 · DOI: 10.4103/0976-500X.142436 · 2014

    Pharmacovigilance (PV) is the branch dealing with adverse drug reactions (ADRs), their recognition, and reporting. ADR is defined by the World Health Organization (WHO) as a response to a drug that is noxious, unintended…

  2. Article

    Kshitij S. Jadhav, Padmaja A. Marathe

    pp. 250–252 · DOI: 10.4103/0976-500X.142439 · 2014

    Glutamate increases dopamine levels in the nucleus accumbens leading to ethanol dependence. Since glutamate transporter 1 (GLT1) is responsible for the removal of synaptic glutamate, up-regulation of GLT1 attenuates etha…

  3. Article

    Gudapati Bhanu Naga Sireesha, Pramil Tiwari, Satinder Gombar, Sanjay D’Cruz, Atul Sachdev

    pp. 252–254 · DOI: 10.4103/0976-500X.142441 · 2014

    This 3‑month observational study was carried out at the ICUs of a public tertiary care hospital. ICUs with 14 bed capacity handle all patients who require ICU level care. Only patients with >24 h of ICU stay and who were…

  4. Article

    Sumit Mehndiratta

    pp. 254–255 · DOI: 10.4103/0976-500X.142444 · 2014

    Dosing errors are not uncommon in day-to-day clinical practice in children. Pediatric patients are more vulnerable to adverse drug events because of small body size and need for weight based dosing. Among various reasons…

Case Report

  1. Article

    Muthiah Palaniappan, Sandhiya Selvarajan, Sureshkumar Srinivasamurthy, Adithan Chandrasekaran

    pp. 256–257 · DOI: 10.4103/0976-500X.142446 · 2014

    A 59 year old female consumer was started on therapy with oyster shell calcium in combination with vitamin D3 and she presented with swelling below the ear, after two doses. She stopped the drug by herself and the swelli…

  2. Article

    Anjana Rao Kavoor, Sayantanava Mitra, Supriya Kumar Mondal, Basudeb Das

    pp. 258–260 · DOI: 10.4103/0976-500X.142448 · 2014

    The occurrence of manic/hypomanic switch in patients being treated with risperidone has been reported by various authors, and they have described a variety of strategies for their management. In this report, we describe …

  3. Article

    Aniruddha Basu, Amit Jagtiani, Rajiv Gupta

    pp. 261–264 · DOI: 10.4103/0976-500X.142449 · 2014

    Catatonia is mostly caused by different neuropsychiatric conditions. We report a case of a 30 year old man suffering from both alcohol and benzodiazepine dependence who exhibited catatonic features soon after stopping th…

  4. Article

    Radhika Soanker, Shobha Jagdish Chandra Udutha, Malladi V S Subbalaxmi, YSN Raju

    pp. 265–267 · DOI: 10.4103/0976-500X.142452 · 2014

    Viral enteritis is an important gastrointestinal disorder in human immunodeficiency virus (HIV)‑infected patients. Cytomegalovirus (CMV) is the most common opportunistic agent in these patients. As ganciclovir and tenofo…

  5. Article

    Sachin R. Agrawal, Atul Rajput, A. P. Jain

    pp. 268–270 · DOI: 10.4103/0976-500X.142453 · 2014

    Leukocytoclastic vasculitis (LCV), also known as hypersensitivity vasculitis is a small vessel inflammatory disease which mainly involves the postcapillary venules. A 17‑year‑old girl developed palpable purpura over lowe…

  6. Article

    Andreu Massot, Ana Gimenez-Arnau

    pp. 271–274 · DOI: 10.4103/0976-500X.142456 · 2014

    Severe skin reactions occur less frequently with eslicarbazepine (ESL) than with the other aromatic anticonvulsants. We report the first case of cutaneous adverse drug reaction (CADR) to ESL and co‑sensitization between …

News and Views

  1. Article

    Sangeeta Bhanwra, Kaza Ahluwalia

    pp. 275–275 · DOI: 10.4103/0976-500X.142458 · 2014

    There has been recent news of association between acetaminophen and risk of hearing loss. Does it raise the bar of safety against indiscriminate use of the drug? National Institute of Health (NIH), USA, funded two prospe…

Mini Manuscript

  1. Article

    Jatinder Singh

    pp. 276–7 · DOI: 10.4103/0976-500X.142462 · 2014

    Dr. Anna Remington and Jake Fairnie, cognitive neuroscientists, chose to bridge the gap between the easy availability of literature and the lack of time and resources by harnessing the power of the internet by developing…

Molecules of the Millennium

  1. Article

    Harmeet Kaur Bhatia, Harmanjit Singh, Nipunjot Grewal, Navreet Kaur Natt

    pp. 278–284 · DOI: 10.4103/0976-500X.142464 · 2014

    Hepatitis C currently infects more than 170 million people around the world, leading to significant morbidity and mortality. The current standard of care for HCV infection, including one of the two protease inhibitors, t…