Journal of Pharmacology and Pharmacotherapeutics
Volume 6, Issue 2
2015 · pp. 61–122 · 17 articles
- Volume
- 6
- Issue
- 2
- Published
- 2015
- Pages
- 61–122
- Articles
- 17
- Sections
- 8
- ISSN
- Print - 0976-500X, Online - 0976-5018
- Journal
- JPP
In this issue
Editorial
- Forum Article
Amitav Banerjee
pp. 61–62 · DOI: 10.4103/0976-500X.155480 · 2015
Review Article
- Review
Loganathan Gayathri, Dharumadurai Dhanasekaran, Mohammad A. Akbarsha
pp. 63–70 · DOI: 10.4103/0976-500X.155481 · 2015
Over several decades, animals have been used as models to investigate the human‑specific drug toxicity, but the outcomes are not always reliably extrapolated to the humans in vivo. Appropriate in vitro human‑based experi…
- Review
Marianne Frieri, William Heuser, Joshua Bliss
pp. 71–76 · DOI: 10.4103/0976-500X.155482 · 2015
Recently introduced into the market, belimumab (Benlysta) is a monoclonal antibody that has potential clinically efficacious applications for the treatment of lupus nephritis. Lupus nephritis is a major complication of s…
Research Paper
- Article
Takashi Kato, Ryoichi Sakiyama, Kiyomasa Oka, Toshikazu Nakamura
pp. 77–82 · DOI: 10.4103/0976-500X.155483 · 2015
Objectives: To ascertain the positions of sulfated groups for HGF‑inducing activity using differently sulfated heparin disaccharides and to investigate whether the heparin disaccharide elevates HGF levels in plasma in vi…
- Article
Jayanthi Mathaiyan, Tanvi Jain, Biswajit Dubashi, K Satyanarayana Reddy, Gitanjali Batmanabane
pp. 83–87 · DOI: 10.4103/0976-500X.155484 · 2015
Objective: To estimate the frequency and type of prescription errors in patients receiving cancer chemotherapy. Settings and Design: We conducted a cross‑sectional study at the day care unit of the Regional Cancer Centre…
Research Letter
- Article
Mohd Masnoon Saiyed, Aarohi Prajapati, Gaurang Shah
pp. 88–89 · 2015
The lack of pediatric drug labeling is a long-standing problem for prescribers and drug regulatory bodies. As a result, medicines are prescribed in an off-label manner, which is inconsistent with its approved prescribing…
- Article
Niti Mittal, Mahesh C. Gupta
pp. 91–93 · DOI: 10.4103/0976-500X.155486 · 2015
Causality assessment of adverse events (AEs) is the standardized and detailed assessment of individual case safety reports for the likelihood of involvement of the suspected drug/s in causing the particular AE. The basic…
Commentary
- Article
Subramani Parasuraman, Ramasamy Raveendran, K. K. Mueen Ahmed
pp. 94–95 · DOI: 10.4103/0976-500X.155487 · 2015
Case Report
- Article
Henrik Horwitz, Vidar A. Woeien, Linda Wiuff Petersen, Espen Jimenez‑Solem
pp. 98–99 · DOI: 10.4103/0976-500X.155488 · 2015
The adverse drug event manager of the Capital Region of Denmark received a report of a 65‑year‑old male with type II diabetes and long‑lasting treatment with indapamide. In addition, he had a history of a high consumptio…
- Article
Kamlesh J Upadhyay, Sarita J Parmar, Rohan Pravinbhai Parikh, Prashant K Gauswami, Nikunj Dadhaniya, Abhilash Surela
pp. 100–102 · DOI: 10.4103/0976-500X.155489 · 2015
This is a rare case report of a 30‑year‑old male, who was admitted to the Maxillofacial Surgery Department of the Dental College for a malunited fracture of the mandible and zygomatic bones. He was given oral medications…
- Article
Santwana Mahar, Mahima Malhotra
pp. 103–104 · DOI: 10.4103/0976-500X.155490 · 2015
Dexamethasone‑induced withdrawal seizure, which is a very rare and uncommon event, occurred after discontinuation of steroid therapy that was taken to increase weight by the patient. The pathogenesis is not well understo…
- Article
Atul Sharma, Ekta Arora, Harmanjit Singh
pp. 105–106 · DOI: 10.4103/0976-500X.155491 · 2015
Thalassemias comprise a group of hereditary blood disorders. Thalassemia major presents with anemia within the first 2 years of life requiring frequent blood transfusions for sustaining life. Regular blood transfusions l…
- Article
Subramaniam Keerthi, Murugaiyan Rangaraj, Kaliaperumal Karthikeyan
pp. 107–109 · DOI: 10.4103/0976-500X.155492 · 2015
Pustular psoriasis is characterized by abrupt onset of macroscopic pustules associated with erythema and symptoms of burning pain and constitutional symptoms. There are several precipitating factors, both physiological s…
- Article
Balasekar Premkumar, Muppavarapu Srinivasa Murthy, Karuppasamy Rajagopal, Vadivelmurugan Nagasubramani Nagaprabu, Sree Madhuri Ponugupati
pp. 110–113 · DOI: 10.4103/0976-500X.155493 · 2015
A patient suffering from rheumatoid arthritis who had extreme adrenal suppression as a result of chronic use of herbal medicines presented with complications of adrenal suppression such as muscle weakness. He also had ps…
- Article
Kaliaperumal Mathan, Venkatesan Muthukrishnan, Vikas Menon
pp. 114–115 · DOI: 10.4103/0976-500X.155494 · 2015
Antipsychotic‑induced edema is uncommonly encountered in clinical practice. We report a case of tender pitting pre‑tibial edema with olanzapine in a woman with no medical comorbidities. The peculiar distribution of edema…
- Article
Ashok K. Dubey, Shailendra S. Handu, Pramod K. Mediratta
pp. 118–121 · DOI: 10.4103/0976-500X.155496 · 2015
Primary insomnia is mainly treated with drugs acting on benzodiazepine receptors and a few other classes of drugs used for different co‑morbidities. A novel approach to treat insomnia has been introduced recently, with t…
Correspondence
- Article
D = log10 of the dilution factor
pp. · DOI: 10.4103/0976-500X.155495 · 2015
Assessment of vaccine potency is often carried out by veterinarians in animal house in biological units. The more reliable method used for this assessment is Spearman and Karber. The calculations involved in the assessme…