Journal of Pharmacology and Pharmacotherapeutics
Volume 7, Issue 4
2016 · pp. 155–198 · 10 articles
- Volume
- 7
- Issue
- 4
- Published
- 2016
- Pages
- 155–198
- Articles
- 10
- Sections
- 6
- ISSN
- Print - 0976-500X, Online - 0976-5018
- Journal
- JPP
In this issue
Review Article
- Review
Ajay Gupta, Pramod Kumar Sharma, Arup Kumar Misra, Surjit Singh
pp. 155–158 · DOI: 10.4103/0976-500X.195897 · 2016
Gout is a metabolic disorder that usually presents as recurrent episodes of acute arthritis due to deposition of crystals in joints and cartilages. Despite the availability of several drugs for gout, its management is st…
Research Paper
- Article
Rupadevi Muthaian, Rajaa Muthu Pakirisamy, Subramani Parasuraman, Ramasamy Raveendran
pp. 159–164 · DOI: 10.4103/0976-500X.195898 · 2016
Objective: To investigate the association of hypertension coexisting with diabetes mellitus with oxidative stress and inflammation in the kidneys of streptozotocin (STZ)‑induced diabetic rats. Materials and Methods: Male…
- Article
Jayesh Dalpatbhai Solanki, Bhakti P. Gadhavi, Amit H. Makwana, Hemant B. Mehta, Chinmay J. Shah
pp. 165–170 · DOI: 10.4103/0976-500X.195900 · 2016
Objectives: To study the effect of disease duration, treatment and risk factors on QTc interval among young hypertensives. Materials and Methods: A case–control study was conducted on 142 hypertensives (60 males, 82 fema…
- Article
Ganesh Dakhale, Yogesh Tathod, Seema Patel, Sonali Pimpalkhute, Latesh Raghute, Ajita Khamkar
pp. 171–176 · DOI: 10.4103/0976-500X.195901 · 2016
Objective: To compare the efficacy, safety, and cost‑effectiveness of rupatadine and olopatadine in patients of allergic rhinitis (AR). Materials and Methods: A 2‑week, single‑centered, randomized, double‑blind, parallel…
- Article
Sumalya Sen, Anitha Thomas, Saibal Das, Jayanta Kumar Dey, Abraham Peedicayil, Vinotha Thomas
pp. 177–181 · DOI: 10.4103/0976-500X.195902 · 2016
Objective: To investigate the inhibitory effect of tadalafil on the contractility of isolated nonpregnant human myometrium. Materials and Methods: The ability of tadalafil (25, 40, and 63 µM) to inhibit 55 mM KCl‑induced…
Research Letter
- Article
Amit Kumar, Vandana Vandana, Ahmad Nadeem Aslami
pp. 182–3 · DOI: 10.4103/0976-500X.195903 · 2016
The data were analyzed by descriptive and inferential statistics. Odds ratio and Chi-square test were applied. The sum of percentages is not always 100% as some questions contained multiple responses. A total of 308 comp…
Case Report
- Article
Md. Shahid Alam, K. V. Praveen Kumar
pp. 184–186 · DOI: 10.4103/0976-500X.195904 · 2016
A variety of systemic drugs including corticosteroids, amiodarone and antipsychotics have been known to cause cataract formation. Typical antipsychotics such as chlorpromazine have been reported to cause cataract formati…
- Article
Md. Shahid Alam, Swati Agarwal
pp. 187–9 · DOI: 10.4103/0976-500X.195905 · 2016
Isotretinoin a synthetic analogue of vitamin A is primarily used for cystic acne not responding to conventional treatment. Several ocular side effects including blurring of vision, decreased dark adaptation, corneal opac…
Molecules of Millennium
- Article
Faizan Mazhar, Nafis Haider
pp. 190–3 · DOI: 10.4103/0976-500X.195906 · 2016
The treatment of hypercholesterolemia entered in a new phase of development with the introduction of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in the market. The Food and Drug Administration and Eu…
- Article
Afroz Abidi, Pooja Shukla, Ali Ahmad
pp. 194–198 · DOI: 10.4103/0976-500X.195920 · 2016
Dry eye disease (DED) is an inflammatory disorder of ocular surfaces leading to severe disability, especially in the elderly age group. The mainstay of therapy includes artificial tears, punctual plugs, topical anti- inf…