Volume 8, Issue 1

M. K. Unnikrishnan

pp. 1–2 · DOI: 10.4103/jpp.JPP_12_17 · 2017

Today’s digital revolution is forcing the healthcare practitioner to read too much, but learn very little. Contemporary knowledge systems have disintegrated into minutiae, focusing more and more on intricacies devoid of …

Poonam Nehra, Vrinda Oza, Vandana Parmar, Pooja Fumakiya

pp. 3–7 · DOI: 10.4103/jpp.JPP_109_16 · 2017

Objective: To compare the effect of addition of fentanyl and clonidine as adjuvants to bupivacaine and lignocaine in peribulbar block. Methods: The study was conducted on 105 adult patients of either sex, of ASA grade I …

Nao Nishijo, Yasuhiro Tsuji, Kazuhisa Matsunaga, Masahiko Kutsukake, Fumiyasu Okazaki, Shiro Fukumori, Hidefumi Kasai, Yoichi Hiraki, Ippei Sakamaki, Yoshihiro Yamamoto, Yoshiharu Karube, Hideto To

pp. 8–13 · DOI: 10.4103/jpp.JPP_167_16 · 2017

Objective: To investigate the relationship between renal function and linezolid (LZD)‑induced thrombocytopenia and elucidate the underlying mechanism using a chronic renal disease (CRD) mouse model. Materials and Methods…

Nasser Ghaly Yousif, Najah R. Hadi, Alaa Manea Hassan

pp. 14–20 · DOI: 10.4103/jpp.JPP_153_16 · 2017

Objective: To investigate the mechanistic pathway of both indocyanine green (ICG)‑001 in attenuated endotoxemia‑induced cardiac depression through downregulation cardiac Wnt/ β‑catenin cell signaling. Materials and Metho…

Anant Mahaveer Khot, H. V. Anuradha, V. S. Prakash, M. C. Shivamurathy

pp. 21–27 · DOI: 10.4103/jpp.JPP_168_16 · 2017

Objective: To evaluate the efficacy and tolerability of ranolazine as an add‑on drug in chronic stable angina patients and the impact of ranolazine on the quality of life in chronic stable angina patients receiving other…

Charanraj Goud Alladi, Anbarasan Mohan, Deepak Gopal Shewade, Ravi Philip Rajkumar, Surendiran Adithan, Karthick Subramanian

pp. 28–32 · DOI: 10.4103/jpp.JPP_197_16 · 2017

Objective: To determine the adverse drug reaction (ADR) profile of risperidone and their association with dopamine (DRD2 − 141 C Ins/ Del/rs1799732) and serotonin receptor (5HTR2C −759 C>T/rs3813929) gene polymorphisms i…

Ashwin Kamath, Sudhakar Pemminati

pp. 33–34 · DOI: 10.4103/jpp.JPP_173_16 · 2017

Sir, Vitamin B12 deficiency is a common nutritional disorder characterized by hematological and neurological manifestations. Cyanocobalamin (CNCbl) or hydroxocobalamin (OHCbl) have been the traditional B12 formulations r…

Caihong Qu, Ying Lu, Weimin Liu

pp. 35–37 · DOI: 10.4103/jpp.JPP_93_16 · 2017

A 60-year-old male patient developed hyperpyrexia, cough, expectoration with blood-stained sputum, mouth ulcers, and suppurative tonsillitis after receiving 35 days of combination treatment with leflunomide (LEF) and low…

Pritam Sureshchandra Kataria, Pradip Piraji Kendre, Apurva A. Patel

pp. 38–40 · DOI: 10.4103/jpp.JPP_182_16 · 2017

Central nervous system (CNS) toxicity has been reported in approximately 10%–30% of patients receiving intravenous infusions of ifosfamide. Encephalopathy is a rare but serious CNS adverse reaction in these patients, and…

V. S. Gokul Krishnan, Sharath Madhyastha, Kusugodlu Ramamoorthi, Raviraj V. Acharya, Vinaya Gopalaswamy

pp. 41–43 · DOI: 10.4103/jpp.JPP_174_16 · 2017

We present a case of pleural tuberculosis (TB) in a patient on infliximab for ankylosing spondylitis. A 36-year-old male presented to our hospital with low back ache of inflammatory type along with multiple symmetric inf…