Volume 12, Issue 1

Efficacy and Safety Comparison between Pioglitazone and Linagliptin in Combination with Metformin among Patients with Type 2 Diabetes Mellitus: A Meta‑Analysis of Randomized Controlled Trials

Omaimah Toufiq, Syed Wasif Gillani, Farhanah Mohamed, Nafis Pasha, Muhsina Chiraparambil, Affana Parveen

pp. 1–9 · DOI: 10.4103/jpp.JPP_154_20 · Published 2021

Objective: To compare the safety and efficacy of linagliptin with pioglitazone in combination therapy of metformin for the management of type 2 diabetes mellitus (T2DM). Materials and Methods: A meta‑analayis research de…

Comparison of Intravenous Ramosetron and Ondansetron as Prophylaxis for Postoperative Nausea and Vomiting following General Anesthesia

Sonali Opneja, Shirley Ann D Souza, Roopesh Sureshan, Pabitra Ghoshal

pp. 10–13 · DOI: 10.4103/jpp.JPP_163_20 · Published 5 July 2021

Objective: To compare the efficacy and side effects of 5HT3 antagonists, ramosetron, and ondansetron as prophylaxis for postoperative nausea and vomiting (PONV) following general anesthesia. Materials and Methods: One hu…

Effect of HMG-Co-A Reductase Inhibitors on Cardiac Autonomic Neuropathy in Diabetic Patients

Aarya Jitendra Kshirsagar, Yogita Karandikar, Leena Phadake

pp. 14–19 · DOI: 10.4103/jpp.JPP_166_20 · Published 2021

Objective: To observe the effect of statins on cardiac autonomic neuropathy in patients with diabetes and to study the correlation between cardiac autonomic neuropathy as assessed by cardiac autonomic reflex tests (CARTs…

Antibacterial Use in Admitted Patients of a Super Speciality Hospital in Western India

Sharan Shyam, Sanjay Jaiswal

pp. 20–22 · DOI: 10.4103/jpp.JPP_156_20 · Published 5 July 2021

Protamine-Induced Hypotension and Pulmonary Arterial Hypertension

Nidheesh Chooriyil, Doyce Jom, Prabitha Panattil, Syam Sreedharan

pp. 23–25 · DOI: 10.4103/jpp.JPP_157_20 · Published 5 July 2021

Protamine is a routinely used safe antidote for heparin reversal in cardiovascular surgeries. Protamine was first introduced to prolong the action of insulin preparations. As protamine interacts with platelets and fibrin…

Relugolix: A Novel Gonadotropin‑Releasing Hormone Antagonist for Prostate Cancer

Merin Babu, Keechilat Pavithran

pp. 26–28 · DOI: 10.4103/jpp.jpp_170_20 · Published 5 July 2021

Androgen deprivation therapy (ADT) is currently the mainstay of treatment for advanced prostate cancer. The peptide formulations of gonadotropin‑releasing hormone (GnRH) antagonists need to be given subcutaneously every …