Volume 12, Issue 2

Career Vistas for Indian Medical Pharmacologists: A Comprehensive Review

Avinash Arivazhahan, Gerard Marshall Raj, Deepthi Shridhar Puttur, Sarjana Atal, Manu Mathew George, Laxminarayana Bairy

pp. 29–36 · DOI: 10.4103/jpp.jpp_37_21 · Published 17 September 2021

Medical postgraduation in India is available across various disciplines, one among them being pharmacology. As with the other MD courses, MD Pharmacology is a 3-year-long course that involves strenuous theoretical, pract…

Is a Glucocorticoid Antagonist a Potential Treatment Alternative for Antipsychotic‑Induced Weight Gain?

Wisam Al Jumaili, Chintan Trivedi, Kaushal Shah, Mahwish Adnan, Zeeshan Mansuri, Shailesh Jain

pp. 37–41 · DOI: 10.4103/jpp.jpp_33_21 · Published 17 September 2021

Objective: To evaluate the efficacy and safety of mifepristone as a new treatment modality for antipsychotic-induced weight gain. Methods: We searched databases up to March 2021, for the published English‑language litera…

Fostemsavir, a Drug with Novel Mechanism for the Treatment of HIV-1 Infection

Raman Palanisamy Priyadharsini, C. M. Divyashanthi, Dhivya Elango

pp. 42–46 · DOI: 10.4103/jpp.jpp_19_21 · Published 17 September 2021

HIV is a global problem with increased mortality and morbidity. The highly active antiretroviral therapy is effective in reducing the HIV RNA and improving the immune response. The drugs in the current regimen have certa…

Vitamin D3 Attenuates Type 3 Diabetic‑Associated Cognitive Deficits in Rats through Regulating Neurotrophins and Enhancing Cholinergic Transmission Pathway

Yahya Abdullah Al-Zahrani, Mai A. Alim A. Sattar, Sameer E. Al-Harthi, Ayed A. Alkatheeri, Yahya Mohammed Al-Zahrani

pp. 47–53 · DOI: 10.4103/jpp.jpp_20_21 · Published 17 September 2021

Objective: To examine the protective effect of Vitamin D3 against Type 3 diabetes-induced cognitive dysfunction in rats. Materials and Methods: Type 3 diabetes was induced by a high‑fat diet plus streptozotocin in rats. …

Effect of Atorvastatin and Rosuvastatin on the Glycemic Control in Patients with Type II Diabetes Mellitus: A Comparative, Randomized, Double-Blind Study

Mohini Sachin Mahatme, Mukunda Bharat Bargade, Sachin K. Hiware, M. M. Motlag

pp. 54–60 · DOI: 10.4103/jpp.jpp_8_21 · Published 17 September 2021

Objectives: To compare the effects of atorvastatin and rosuvastatin in type II diabetes mellitus (T2DM) patients with dyslipidemia. Materials and Methods: Eighty patients with history of T2DM of more than 3 months durati…

Therapeutic Drug Monitoring of Imatinib in Patients of Chronic Myeloid Leukemia – Chronic Phase

Harshit Khurana, Ashwini Kumar, Abha Khurana, Kumar Abhisheka, Vijoy Kumar Jha

pp. 61–67 · DOI: 10.4103/jpp.jpp_28_21 · Published 17 September 2021

Introduction: Tyrosine kinase inhibitor is recommended for the initial management of chronic phase chronic myeloid leukemia (CP CML) based on the more favorable balance of toxicity and long‑term disease control. Backgrou…

Role of Vitamin B Complex as an Add-on Therapy to Diclofenac in Patients with Primary Osteoarthritis of the Knee

Jasmine Kaur, Seema Rani, Anil Gulia, Garima Bhutani, Sanjeev Kumar, Arvind Narwat

pp. 68–72 · DOI: 10.4103/jpp.jpp_32_21 · Published 17 September 2021

Objective: This study was conducted with the aim to evaluate the efficacy and safety of Vitamin B complex as an add‑on therapy to diclofenac in patients with primary osteoarthritis(OA) of the knee. Materials and Methods:…

Correlation between Breakthrough Seizures and Serum Level of Phenytoin and Valproate in Indian Patients

Neena Katoch, Ankit Bhardwaj, Kapil Suchal, Sangeeta Sharma

pp. 73–78 · DOI: 10.4103/jpp.jpp_3_21 · Published 2021

Objectives: To determine the optimum range of phenytoin (PHT) and valproate (VAP) levels and find out the critical drug levels below which chances of breakthrough seizures increase in North Indian population. Methodology…

Assessment of Potential Drug ‑ Drug Interaction among the Patients Receiving Cancer Chemotherapy: A Cross‑sectional Study

K. M. Venkatesh, Swathi Acharya, Rajendra Holla

pp. 79–85 · DOI: 10.4103/jpp.jpp_16_21 · Published 2021

Objectives: To identify and assess the various potential drug‑drug interactions (pDDIs) among the patients receiving cancer chemotherapy, using the database from Lexicomp® Solutions with the ultimate goal of raising awar…

Prevalence, Risk Factors, and Prescribing Trends in Chronic Renal Failure in the Indian Population

Jalpa Suthar, Rutvi D. Patel, Shubha Desai

pp. 86–90 · DOI: 10.4103/jpp.JPP_149_20 · Published 17 September 2021

Objective: To estimate the prevalence of Chronic renal failure (CRF) in the Indian subcontinent and to identify risk factors and treatment regimens for CRF. Methods: A prospective observational study was carried out for …

Impact of Oral Cannabis Consumption on Health: A Cross-sectional Study

Sneha R. Ambwani, Rimplejeet Kaur

pp. 91–93 · DOI: 10.4103/jpp.JPP_143_20 · Published 17 September 2021

Risk Factors and Prescription Pattern among Patients with Congestive Heart Failure

Jison Jose, Betty Baby, Shabeer Ahammed, Sharad Chand, Nandakumar UP, Vinay BC, K. Subramanyam, Juno J. Joel

pp. 94–96 · DOI: 10.4103/jpp.jpp_25_21 · Published 17 September 2021

Evaluation of Recent Prescription Pattern in Cornea Clinic of a Tertiary Care Hospital: A Developing Country’s Perspective

Niraj Niraj, Nusrat Shafiq, Chakrant Mothsara, Gaurav Garg, Amit Gupta, Samir Malhotra

pp. 97–99 · DOI: 10.4103/jpp.JPP_34_21 · Published 17 September 2021

Monday Blues – Rare Cause of Hypoglycemia in a Child with Leukemia

Gowshika Krishnakumar, Dhaarani Jayaraman, Dhivyalakshmi Jeevarathnam, Peter Prasanth Kumar Kommu, Julius Xavier Scott

pp. 100–101 · DOI: 10.4103/jpp.jpp_57_21 · Published 17 September 2021

Hypoglycemia in a child with acute lymphoblastic leukemia (ALL) often makes the clinician think of sepsis or metabolic disturbances due to relative adrenal insufficiency with steroid withdrawal. We report a rare scenario…

A Survival Case of Premature Infant with Hepatoblastoma (Fetal Pattern) along with Other Serious Comorbidities and Surgical Interventions

Mohammed Fardan, A. Priya Shiva, Aswathy M. Shaji, K. Arun Chander Yadav

pp. 102–105 · DOI: 10.4103/jpp.JPP_146_20 · Published 17 September 2021

An estimated ratio (i.e., 1 in 10) babies are born too early every year. Roughly 1 million children die each year due to impediments raised pertaining to preterm birth. One such extreme preterm male baby was presented in…