Journls JOURNAL OF PHARMACOLOGY AND PHARMACOTHERAPEUTICS Volume 14 · Issue 2 2023 · pp. 93–162
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Cover: Journal of Pharmacology and Pharmacotherapeutics

Journal of Pharmacology and Pharmacotherapeutics

Volume 14, Issue 2

2023 · pp. 93–162 · 7 articles

Volume
14
Issue
2
Published
2023
Pages
93–162
Articles
7
Sections
3
ISSN
Print - 0976-500X, Online - 0976-5018
Journal
JPP

In this issue

Review Article

  1. Review

    Rationalization of Antibiotic Prescription: Modulation of the Gut Microbiome and Possibilities of Minimizing the Risks for the Development of Antibiotic Resistance—A Narrative Review

    Ashok Kumar, Aman Shukla, Pottathil Shinu, Bijo Mathew, Shashank Kailkhura, Pranjal Pratap Singh, Anroop B. Nair

    pp. 93–106 · DOI: 10.1177/0976500X231189341 · Published 2023

    Antimicrobial resistance (AMR) is a serious global health issue, and it is greatly influenced by the gut flora. The rationalization of antimicrobial doses in clinical studies is crucial for preventing AMR. This review an…

  2. Review

    Dengue Virus: Molecular Biology and Recent Developments in Control Strategies, Prevention, Management, and Therapeutics

    Almonther Abdullah Hershan

    pp. 107–124 · DOI: 10.1177/0976500X231204401 · Published 2023

    Dengue is a viral infection caused by one of four serotypes of dengue virus (DENV), which is responsible for causing potentially life-threatening disease and substantial public health as well as economic burden worldwide…

Research Article

  1. Article

    Allelic Variants in the Warfarin-related Genes VKORC1 and CYP2C9 in a Western Saudi Population

    Amina M. Bagher, Wedyan S. Alharbi, Lamees S. Gadi, Lenah S. Binmahfouz, Rawan H Hareeri

    pp. 125–132 · DOI: 10.1177/0976500X231189351 · Published 2023

    Objectives: To investigate the allele and genotype frequencies of the warfarin-related genes VKORC1 (-1639G>A), CYP2C9*2, and CYP2C9*3 among healthy Saudis. Materials and Methods: This cross-sectional study involved 125 …

  2. Article

    Quercetin Exerts a Protective Effect on Ischemic Stroke-induced Memory Deficits in Mice

    Chrismawan Ardianto, Dewi Lestari, Luthfia Hany Primadani, Dwi Retno Puspitasari, I Nengah Budi Sumartha, Khoirotin Nisak, Aniek Setiya Budiatin, Dewi Wara Shinta, Mareta Rindang Andarsari, Farida Ifadotunnikmah, Amar Daud Iskandar Abdullah, Mahardian Rahmadi, Junaidi Khotib

    pp. 133–141 · DOI: 10.1177/0976500X231189343 · Published 2023

    Objectives: Brain injury resulting from an ischemic stroke affects cognitive performance by disrupting the hippocampus. Several processes are involved in brain injury progression, including inflammation, glutamate excito…

  3. Article

    N-Acetyl-l-Cysteine Ameliorations Renal Function Early After Renal Ischemia and Reperfusion; it is not Protective over a Long Term under a High-Sodium Diet in Rats

    Rafael Canavel Pereira, Carolina Martinez Romão, Beatriz Santos Geoffroy Corrêa, Wagner Vasques Dominguez, Luzia Naôko Shinohara Furukawa

    pp. 142–152 · DOI: 10.1177/0976500X231189327 · Published 2023

    Objectives: To evaluate the early and late effects of N-acetyl-l-cysteine (NAC) treatment on renal ischemia and reperfusion (I/R) insult in adult Wistar rats influenced by chronic high sodium (HS) intake. Materials and M…

  4. Article

    Pediatric Antimicrobial Usage in a Secondary Care Hospital in Ras Al Khaimah, United Arab Emirates

    Sarah Dawood, Yasmin Sharifian, Masah Mardini, Duaa Jawhar, Laxminarayana Kurady Bairy, Suresh Kumar Srinivasamurthy

    pp. 153–159 · DOI: 10.1177/0976500X231203845 · Published 2023

    Objectives: To assess the pattern of antimicrobial use among pediatric inpatients in a secondary care hospital in the United Arab Emirates. Materials and Methods: The prospective study was conducted based on the electron…

Letter to the Editor

  1. Article

    The Science of Antioxidants: Balancing the Pros and Cons for Our Health

    Mueen Ahmed K. K.

    pp. 160–162 · DOI: 10.1177/0976500X231182792 · Published 2023

    Free radicals are highly reactive molecules that can cause damage to cells, tissues, and organs within the body. These unstable molecules are generated through normal metabolic processes in the body but can also be produ…