Volume 6, Issue 4

Editorial

1. Forum Article

   Trivializing assessment: A key factor in undermining the standards of medical education

   Manikandan S

   pp. 195–197 · DOI: 10.4103/0976-500X.171875 · Published 2015

   Examinations are an indispensable part of education both for students and teachers. The practical/clinical examination is an integral part of all summative assessments in medical training. In many departments throughout …

Research Paper

1. Article

   A comparative study of the clinical efficacy and safety of agomelatine with escitalopram in major depressive disorder patients: A randomized, parallel‑group, phase IV study

   Chetan S. Urade, Sunil M. Mahakalkar, Prashant G. Tiple

   pp. 198–203 · DOI: 10.4103/0976-500X.171883 · Published 2015

   Objective: To compare the efficacy of agomelatine with escitalopram in the treatment of major depressive disorder (MDD), improve sleep in MDD patients and study the adverse effects of agomelatine. Materials and Methods: …

2. Article

   Vasorelaxation of goat mesenteric artery is mediated by endothelial Na+‑K+‑ATPase

   R. Sathiskumar, Bimal Prasanna Mohanty, Subas Chandra Parija

   pp. 204–210 · DOI: 10.4103/0976-500X.171884 · Published 2015

   Objective: To examine the role of Na+‑K+‑ATPase and K+ channels in mediating vasorelaxation in the superior mesenteric artery of Capra hircus. Materials and Methods: Goat superior mesenteric artery (GSMA) was cut into 1.…

Case Report

1. Article

   Successful management of malignant hyperpyrexia syndrome in a pediatric patient: What to do when dantrolene is not available?

   Priyanka Gupta, Geeta Kamal, Mayank Gupta

   pp. 211–213 · DOI: 10.4103/0976-500X.171873 · Published 2015

   Malignant hyperpyrexia syndrome (MHS) is a rare entity and may not be encountered by the anaesthesiologists throughout their professional career. Whenever it manifests can be a challenging task to manage and prove to be …

2. Article

   Mirtazapine withdrawal‑induced mania

   Jitendra Kumar Verma, Satyakam Mohapatra

   pp. 214–215 · DOI: 10.4103/0976-500X.171878 · Published 2015

   Antidepressant withdrawal mania is not a commonly reported occurrence. To date, there is only one published report of hypomanic episode on withdrawal of mirtazapine. A case is presented herein of a patient who experience…

3. Article

   Carbamazepine‑induced hypertension: A rare case

   Preeti Kharb, Niti Mittal, Mahesh C. Gupta

   pp. 216–218 · DOI: 10.4103/0976-500X.171879 · Published 2015

   A 74‑year‑old female with trigeminal neuralgia developed hypertension after the initiation of carbamazepine therapy. The time sequence of start of the suspected drug and onset of hypertension are consistent with the diag…

4. Article

   Case Report A case of losartan-induced severe hyponatremia

   Saibal Das, Sanjib Bandyopadhyay, Anand Ramasamy, V. Vinoth Prabhu, Sudhakar Pachiappan

   pp. 219–221 · DOI: 10.4103/0976-500X.171880 · Published 2015

   This case report outlines a very rare case of losartan-induced severe hyponatremia in a 73-year-old type 2 diabetic patient. The patient was initiated with 50 mg daily oral losartan monotherapy for newly diagnosed modera…

5. Article

   Sodium thiosulfate for the treatment of warfarin‑induced calciphylaxis in a nondialysis patient

   Emily J. Carrell, Allison Bell

   pp. 222–224 · DOI: 10.4103/0976-500X.171882 · Published 2015

   Calciphylaxis or uremic arteriolopathy is a complex process typically seen in patients with end‑stage renal disease, but has also been reported in patients with normal renal function. However, therapies for calciphylaxis…

6. Article

   Kounis syndrome secondary to intravenous cephalosporin administration

   Sunkavalli Venkateswararao, Gopalan Rajendiran, Rathakrishnan Shanmuga Sundaram

   pp. 225–227 · DOI: 10.4103/0976-500X.171877 · Published 2015

   Kounis syndrome is a clinical condition due to hypersensitivity that culminates into acute coronary syndrome (ACS) which can be fatal. A 36‑year‑old male with no conventional coronary risk factors presented elsewhere wit…

7. Article

   Carbimazole‑induced agranulocytosis

   Anisha Mohan, Siby Joseph, Neeraj Sidharthan, Dhanya Murali

   pp. 228–230 · DOI: 10.4103/0976-500X.171881 · Published 2015

   A 47 year old lady with hyperthyroidism for past 1½ years was initially on Carbimazole 20 mg orally then changed to 30 mg (during Hysterectomy) but was taking 10 mg for last 1 year. She had intermittent fever with severe…

8. Article

   Etoricoxib‑ induced pleural effusion: A case for rational use of analgesics

   Nisahan Balasingam, Kumanan Thirunavukarasu, Gowry Selvaratnam

   pp. 231–232 · DOI: 10.4103/0976-500X.171876 · Published 2015

   Pleural effusion caused by drug is an uncommon event in clinical practice. Etoricoxib induced pleural effusion is an extremely rare. We describe a patient with pleural effusion as an adverse drug reaction of etoricoxib.

1. Article

   An upcoming drug for onychomycosis: Tavaborole

   Neha Sharma, Dhruva Sharma

   pp. 236–239 · DOI: 10.4103/0976-500X.171870 · Published 2015

   Fungal infection of the nail as well as nail bed is termed as ‘onychomycosis’. It is caused by dermatophytes, non‑dermatophytic fungal species and yeasts like Candida albicans. It is traditionally treated by topical anti…

Erratum

1. Article

   Erratum: Complete resistance after maximal dose of rocuronium

   pp. 240–240 · DOI: 10.4103/0976-500X.171885 · Published 2015

   In the article titled, “Complete resistance after maximal dose of rocuronium” published in pages 175‑178, issue 3, vol. 6 of Journal of Pharmacology and Pharmacotherapeutics,[1] the name of the fifth author is written in…

2. Article

   Erratum: Inhaled insulin: A “puff” than a “shot” before meals

   pp. 241–241 · DOI: 10.4103/0976-500X.171886 · Published 2015

   In the article titled, “Inhaled insulin: A “puff” than a “shot” before meals” published in pages 126-129, Issue 3, Vol. 6 of Journal of Pharmacology and Pharmacotherapeutics,[1] the name of the seventh author of the arti…