Hypoglycemic Effect of Leucas lavandulaefolia Willd in Alloxan-Induced Diabetic Rats
Chandrashekar KS1★, Prasanna KS2★ Corresponding author
- 1Department of Pharmacognosy, NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore, INDIA.
- 2Department of Community Medicine, Father Muller Medical College, Mangalore, INDIA.
CORRESPONDENCE
Chandrashekar KS
Department of Pharmacognosy, NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore, INDIA.
Volume 1, Issue 4 · pp. 326–329 · PUBLISHED · DOI: 10.4103/0975-1483.59322
ABSTRACT
Leucas lavandulaefolia Willd. is mainly used in Indian folk medicine for the treatment of diabetes mellitus. The oral administration of 0.15, 0.20 and 0.25 g/kg of chloroform extract of the Leucas lavandulaefolia ß owers (LLFEt) for 30 days resulted in a signiÞ cant reduction in blood glucose, glycosylated hemoglobin and an increase in total hemoglobin, and the effect was highly signiÞ cant in the case of 0.25 g/kg. It also prevents decrease in body weight. Oral glucose tolerance test was also performed in experimental diabetic rats in which there was a signiÞ cant improvement in glucose tolerance in animals treated with LLFEt and the effect was compared with glibenclamide. Thus, the study shows that LLFEt has hypoglycemic action.
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KS, C., & KS, P. (). Hypoglycemic Effect of Leucas lavandulaefolia Willd in Alloxan-Induced Diabetic Rats. Journal of Young Pharmacists, 1(4), 326–329. https://doi.org/10.4103/0975-1483.59322