Journal of Young Pharmacists
Volume 1, Issue 4
· pp. 285–384 · 19 articles
- Volume
- 1
- Issue
- 4
- Published
- Pages
- 285–384
- Articles
- 19
- Sections
- 7
- ISSN
- Print - 0975-1483 | Online - 0975-1505
- Journal
- JYP
In this issue
Pharmaceutics
- Article
Effect of Permeation Enhancers on the Release and Permeation Kinetics of Oxytetracycline Hydrochloride Organogel Formulations
Nandini D, Chauhan NS, Chandra A, Pathak K
pp. 285–289 · DOI: 10.4103/0975-1483.59314 · Published
Oxytetracycline HCl is an antibacterial drug used in the treatment of acne vulgaris and dermatitis. Its oral bioavailability is intermediate i.e., 60% and it is rapidly excreted through renal route. This drug has many si…
- Article
Microdosing vs. Therapeutic Dosing for Evaluation of Pharmacokinetic Data: A Comparative Study
Mahajan R, Parvez A, Gupta K
pp. 290–294 · DOI: 10.4103/0975-1483.59315 · Published
Objectives: Human microdosing studies or phase 0 studies have been proposed to supplement pharmacokinetic (PK) studies in animals. In phase 0 studies, extremely low, nonpharmacologically active doses of a drug are given …
- Article
Advanced PEGylation for the Development of Raloxifene Hydrochloride, BCS Class II Drug
Bandela JJ, Anupama CH
pp. 295–300 · DOI: 10.4103/0975-1483.59316 · Published
The aim of this study is to enhance the dissolution rate of raloxifene hydrochloride and to prepare tablets by PEGylation. The high-molecular-weight polyethylene glycols, PEG 15 000 and PEG 35 000, were used for PEGylati…
- Article
Development and Evaluation of Sustained Delivery of Diclofenac Sodium from Hydrophilic Polymeric Beads
Dhanaraju MD, Sundar VD, NandhaKumar S, Bhaskar K
pp. 301–304 · DOI: 10.4103/0975-1483.59317 · Published
Sustained-release polymeric beads containing diclofenac sodium were fabricated with hydrophilic polymers, sodium carboxymethyl cellulose (Na CMC), and sodium alginate (Na alginate). Particulate beads of Na CMC and Na alg…
- Article
Design, Evaluation and Study of Effect of Hydrophilic Polymers on Release Rate of Antiulcer Floating Tablets
Akbari BV, Dholakiya RB, Shiyani BG, Lodhiya DJ, Shastry CS
pp. 305–311 · DOI: 10.4103/0975-1483.59318 · Published
Gastro retentive drug delivery systems are the systems which are retained in the stomach for a longer period of time and thereby improve the bioavailability of drugs. Different approaches for gastro retentive dosage form…
Pharmacognosy
- Article
Chemical Composition of Curcuma Longa Leaves and Rhizome Oil from the Plains of Northern India
Awasthi PK, Dixit SC
pp. 312–316 · DOI: 10.4103/0975-1483.59319 · Published
Hydro distillation of rhizomes and leaves of Curcuma longa resulted in the isolation of 0.36% and 0.53% of oils (w/v) respectively on a fresh weight basis. GC and GC-MS analysis resulted in the identiÞ cation of 73 const…
- Article
An In Vitro Study on the inhibitory Activities of Eugenia jambolana Seeds Against Carbohydrate Hydrolyzing Enzymes
Ahmed F, Chandra JNNS, Timmaiah NV
pp. 317–321 · DOI: 10.4103/0975-1483.59320 · Published
Herbal medicines have been used since prehistoric times by different cultures worldwide for treatment of diabetes. In the present investigation, the effect of untreated and heat-treated aqueous extracts from Eugenia jamb…
- Article
Antihistaminic Effect of Various Extracts of Punica granatum Linn. Flower Buds
Barwal SB, Nirmal Sunil A, Dhasade VV, Patil MJ, Pal SC, Mandal Subhash C
pp. 322–325 · DOI: 10.4103/0975-1483.59321 · Published
Punica granatum Linn. (Punicaceae) ß ower buds are used in the treatment of asthma traditionally, so the present work was undertaken to prove it scientiÞ cally using suitable animal models. Antihistaminic principles are …
Pharmacology
- Article
Hypoglycemic Effect of Leucas lavandulaefolia Willd in Alloxan-Induced Diabetic Rats
Chandrashekar KS, Prasanna KS
pp. 326–329 · DOI: 10.4103/0975-1483.59322 · Published
Leucas lavandulaefolia Willd. is mainly used in Indian folk medicine for the treatment of diabetes mellitus. The oral administration of 0.15, 0.20 and 0.25 g/kg of chloroform extract of the Leucas lavandulaefolia ß owers…
- Article
Antidiabetic Activity of Nerium indicum Leaf Extract in Alloxan-induced Diabetic Rats
Sikarwar MS, Patil MB, Kokate CK, Sharma S, Bhat V
pp. 330–335 · DOI: 10.4103/0975-1483.59323 · Published
This research aims to investigate the antidiabetic activity of Nerium indicum (Family: Apocynaceae) leaf extract in alloxan induced diabetic albino rats. A comparison was made between the action of Nerium indicum extract…
- Article
Protective Effect of Hordeum vulgare Linn. on Acetaminophen- Induced Liver Damage
Shah PA, Parmar MY, Thakkar VT, Gandhi TR
pp. 336–340 · DOI: 10.4103/0975-1483.59324 · Published
The objective of the present study has been to evaluate the hepatoprotective activity of methanolic extract of Hordeum vulgare Linn. (MEHV) seeds against acetaminophen-induced liver damage in rats. Acetaminopheninduced l…
Pharm Chemistry
- Article
Synthesis and Pharmacological Evaluation of Some Quinoline Derivatives as Potential Antiamnesic Agents
Piplani P, Rani A, Sandhir R, Kulkarni SK
pp. 341–350 · DOI: 10.4103/0975-1483.59325 · Published
A deÞ cit of cholinergic neurotransmission is considered to be one of the major causes of disturbance in learning and memory. Among the various therapeutic approaches investigated to enhance cholinergic transmission, ace…
Pharm Analysis
- Article
A Validated Method for Development of Tenofovir as API and Tablet Dosage Forms by UV Spectroscopy
Gnanarajan G, Gupta AK, Juyal V, Kumar P, Yadav PK, Kailash P
pp. 351–353 · DOI: 10.4103/0975-1483.59326 · Published
A simple new spectrophotometric method has been developed for estimation of Tenofovir disoproxil fumarate in bulk and tablet dosage form. Tenofovir disoproxil fumarate is estimated to be 261 nm in triple distilled water.…
- Article
Derivative Spectrophotometry Method for Simultaneous Estimation of Rupatadine and Montelukast in their Combined Dosage Form
Patel PG, Vaghela VM, Rathi SG, Rajgor NB, Bhaskar VH
pp. 351–358 · DOI: 10.4103/0975-1483.59327 · Published
This study describes the development and validation for the simultaneous estimation of rupatadine and montelukast by the Þ rst-order derivative UV spectroscopy method. The quantiÞ cation was achieved by the Þ rstorder de…
- Article
Quantitative Estimation of Efavirenz by High Performance Thin Layer Chromatography
Hamrapurkar P, Phale M, Shah N
pp. 359–363 · DOI: 10.4103/0975-1483.59328 · Published
A simple, accurate, and precise HPTLC method has been developed and validated for the estimation of efavirenz from bulk drug and capsule formulations. The separation was achieved on TLC plates using an appropriate solven…
- Article
New RP-HPLC Method of Miglitol in Tablet Dosage form Including Forced Degradation Studies and Estimation in Spiked Rabbit Plasma
Chittora NC, Shrivastava A, Jain A
pp. 364–370 · DOI: 10.4103/0975-1483.59329 · Published
A simple, accurate, precise, economic, and speciÞ c stability indicating the RP-HPLC method has been developed for the estimation of Miglitol in tablet dosage form and spiked rabbit plasma. Chromatographic separation was…
- Article
Determination of Progesterone in Capsules by High-Performance Liquid Chromatography and UV- Spectrophotometry
Maliwal D, Jain P, Jain A, Patidar V
pp. 371–374 · DOI: 10.4103/0975-1483.59330 · Published
The rapid, simple, and accurate chromatographic (high-performance liquid chromatography) and spectrophotometric method for the determination of progesterone in capsule was elaborated. Methanol was found to be a suitable …
Clinical Pharmacy
- Article
The In-Practice Prescribing Pattern for Antibiotics in the Management of Diabetic Foot: Needs Much More to be done!
Ali N, Rehman S, Imran M, Hussian I, Shehbaz N, Jamshed H, Hayat A, Khan S, Anwar MJ
pp. 375–378 · DOI: 10.4103/0975-1483.59331 · Published
More than 850 patients medication history forms were evaluated, retrospectively, for possible irrationalities in the prescribing pattern of antibiotics for management of hospitalized diabetic foot cases. Primary anti-di…
Pharm Marketing
- Article
Business Method Patents: A Primer
Pol S, Janodia MD, Jagadeesh PC, Bhat KM, Udupa N
pp. 379–384 · DOI: 10.4103/0975-1483.59332 · Published
Business method patent grants to its holder exclusive rights to a particular way of doing business. Business method patents are a relatively new species of patent and there have been several reviews investigating the app…