jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Journal of Young PharmacistsNOW IN
Review

Nanoparticulate Formulation for the Treatment of Different Types of Colon Disease Like Ulcerative Colitis: A Comprehensive Review

Debgopal Ganguly1, Ananta Choudhury1★, Ranabir Chanda2, Hira Das2, Sumit Mitra2, Riya Ghosh2, DeblinaSardar D3★ Corresponding author

  1. 1Faculty of Pharmaceutical Science, Assam Down Town University, Sankar Madhab Path Gandhi Nagar, Panikhaiti, Guwahati, Assam, INDIA.
  2. 2School of Pharmacy, Seacom Skills University, Bolpur, Birbhum, West Bengal, INDIA.
  3. 3Eminent College Of Pharmaceutical Technology, Barasat, Jagannathpur, West Bengal, INDIA.

CORRESPONDENCE

Ananta Choudhury

Faculty of Pharmaceutical Science, Assam Down Town University, Sankar Madhab Path Gandhi Nagar, Panikhaiti, Guwahati, Assam, INDIA.

anantachoudhury@gmail.com

Received: 28-05-2023; Revised: 10-07-2023; Accepted: 28-07-2023.

Volume 15, Issue 4 · pp. 585–588 · PUBLISHED · DOI: 10.5530/jyp.2023.15.82

View on JYP original site ↗

ABSTRACT

It is crucial to use a colon-targeted medication delivery system to treat diseases that start in the colon, such as inflammatory bowel disease, colon cancer, amoebiasis, and irritable bowel syndrome. Through colon targeted drug delivery system, we can give localised treatment to the patient which reduces the chance of toxicity and improves its therapeutic efficacy. The bioavailability of medications for the colon has greatly increased because to recent improvements in oral formulations. But because it is intimately linked to GI Inflammation, it is crucial to make some changes to the Gastrointestinal (GI) physiology to increase the therapeutic effect even more. Due to their structural makeup and smaller size, nanoparticles are often used in the administration of drugs that are specifically targeted for the colon. It is designed in such a way that it promotes aggregation time of drugs at the site of action, supporting localized therapy. This review article mainly focuses on oral nanoparticulate formulations that are targeted for treating Colon related diseases.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Ganguly, D., Choudhury, A., Chanda, R., Das, H., Mitra, S., Ghosh, R., & D, D. (). Nanoparticulate Formulation for the Treatment of Different Types of Colon Disease Like Ulcerative Colitis: A Comprehensive Review. Journal of Young Pharmacists, 15(4), 585–588. https://doi.org/10.5530/jyp.2023.15.82