Volume 15, Issue 4

· pp. 585–776 · 28 articles

Volume: 15
Issue: 4
Published
Pages: 585–776
Articles: 28
Sections: 3
ISSN: Print - 0975-1483 | Online - 0975-1505
Journal: JYP

Review Article Original Artcile Case Report

In this issue

Review Article

Review
Nanoparticulate Formulation for the Treatment of Different Types of Colon Disease Like Ulcerative Colitis: A Comprehensive Review
Debgopal Ganguly, Ananta Choudhury, Ranabir Chanda, Hira Das, Sumit Mitra, Riya Ghosh, DeblinaSardar D
pp. 585–588 · DOI: 10.5530/jyp.2023.15.82 · Published
It is crucial to use a colon-targeted medication delivery system to treat diseases that start in the colon, such as inflammatory bowel disease, colon cancer, amoebiasis, and irritable bowel syndrome. Through colon target…
Review
A Comprehensive Overview of Edible Natural Excipients and their Potential Use in Pharmaceutical Formulation Development
Jahnabi Sarmah, Ananta Choudhury, Himangshu Deka, Debgopal Ganguly, Dhiraj Baishya, Rosamund Jyrwa
pp. 589–594 · DOI: 10.5530/jyp.2023.15.83 · Published
This review aims to explore the prospective scope of excipients obtained from edible natural sources and its unique application in the field of pharmaceutical formulation development. A systematic literature search was c…
Review
Nutraceuticals: Regulatory Landscape and Market Dynamics in the Indian Scenario
Lakshmi Prasanthi Nori, Potti Sowmya, Tippa Madhusree, Kalidindi Venkateswara Raju
pp. 595–603 · DOI: 10.5530/jyp.2023.15.84 · Published
Numerous diseases can be prevented and treated with the help of Nutraceuticals. They have become an integral part of daily food intake for every human due to the increase in lifestyle-related health issues. Ensuring the …
Review
Phytoextract Loaded Nanoemulsions for Age-Defying Effects: A Review
Vaibhav Rastogi, Mayur Porwal, Mukesh Singh Sikarwar, Arun Kumar
pp. 604–615 · DOI: 10.5530/jyp.2023.15.85 · Published
Aging is an inevitable process that results in folds, ridges, and wrinkles in the skin as a result of body mass reduction, insufficient hydration, and breakdown of the connection between the dermis and epidermis. The pro…
Review
Analysis of Mortality, Morbidity, and the Provision of Pharmaceutical Care Services in Intensive Care Admitted Patients–An Overview
Neelima Ganzi, Savitha Rajapur Sanathan, Subhash Chandra Ballekere Jayaram, Easwaran Vigneshwaran, Pramod Kumar Teggina Mat
pp. 616–621 · DOI: JYoungPharm-15-4-616 · Published
Critical care pharmacist in the Intensive Care Unit (ICU) provides pharmaceutical care services to improve the quality of care for ICU patients by identifying and resolving drug-related problems and monitoring drug thera…
Review
Revolutionizing Women's Healthcare: Gender-Sensitive Approach for Women’s Better Healthy Future
Sunil Kardani, Rajesh Hadia, Rajesh Maheshwari, Ghanshyam Parmar, Nirmal Shah, Rahul Trivedi, Sunil Baile
pp. 622–628 · DOI: 10.5530/jyp.2023.15.87 · Published
This novel approach recognizes that healthcare is not a one-size-fits-all endeavor and aims to tailor treatment plans and interventions according to gender and sex. Many people are aware that certain diseases and diagnos…

Original Artcile

Article
Mechanistic Insights into Ipriflavone's Role in Postmenopausal Osteoporosis through Integrated Computational and in vitro Techniques
Anish John, Harsha Ashtekar, Dheeraj Gupta, Pankaj Kumar, Anoop Narayanan V
pp. 629–637 · DOI: 10.5530/jyp.2023.15.88 · Published
Background:Postmenopausal osteoporosis affects a large percentage of the female population worldwide. Understanding the molecular pathways is critical for effective treatment. This study aimed to assess ipriflavone's eff…
Article
Synthetic Identification of New Compounds with Anti-fungal Properties of “1-[3-(2-Hydroxyphenyl)-3-Oxop ropanoyl]- 5,5-Diphenylimidazolidine -2,4-Dione and its Derivatives”
Rohit Jaysing Bhor, Shabnam Babu Shaikh, Shirole Rahul Bapusaheb, Satpute Pankaj Bhausaheb, Mahesh Hari Kolhe
pp. 638–648 · DOI: 10.5530/jyp.2023.15.89 · Published
Background:5, 5-diphenylimidazolidine is a heterocyclic hydrocarbon having unique basic structural characteristics in their molecular structure. In this research; we synthesis various 11 derivatives of -[3-(2-hydroxyphen…
Article
Inhibitory Effects of Lawsone Methyl Ether and Lawsone and their Synergistic Interactions with Acarbose against α-Glucosidase: In silico and in vitro Studies
Muhammad Khan, Muhammad Ajmal Shah, Shabana Bibi, Pharkphoom Panichayupakaranant
pp. 649–658 · DOI: 10.5530/jyp.2023.15.90 · Published
Background:Our previous research highlighted remarkable hypoglycemic and hypolipidemic potentials of lawsone methyl ether (LME or 2-methoxy-1,4-naphthoquinone) and lawsone (2-hydroxy-1,4-naphthoquinone) in diabetic rats …
Article
Bioactive Compounds from Momordica charantia, Nigella sativa, and Anethum graveolens against Metabolic Syndrome: Untangling the Complex Relationship
Rajashekar S Chavan, Nayeem A. Khatib, Vishal S. Patil
pp. 659–670 · DOI: 10.5530/jyp.2023.15.91 · Published
Background: Momordica charantia (MC), Nigella sativa (NS), and Anethum graveolens (AG) are widely utilized vegetables and as an herbal medicines, despite widespread use, there is no evidence of molecular mechanisms of co…
Article
Effect of Hydroalcoholic Extracts of Leaves of Vitex trifolia Linn. on Chronic Inflammation and Tuberculosis
Aryaa A. Ankalikar, Agadi Hiremath Viswanathswamy, Pradeepkumar Ronad
pp. 671–678 · DOI: 10.5530/jyp.2023.15.92 · Published
Background:The experiment was intended to evaluate the effect of Vitex trifolia Linn’s hydroalcoholic extract to treat chronic inflammation. Materials and Methods:Chronic inflammation was induced by injecting 0.25 mL of …
Article
Analytical Standardization and Profiling of Santha Chandrodaya Mathirai - A Siddha Herbo-Mineral Tablet Formulation
Shree Devi Munusamy Sampangi Ramulu, Sathiyarajeswaran Parameswaran, Vinayak Soman, Kirubakaran Narayanan, Rajesh Allu, Shakila Ramachandran, Meenakumari Ramaswamy
pp. 679–686 · DOI: 10.5530/jyp.2023.15.93 · Published
Background: Santha Chandrodaya Mathirai (SSM) [Cāntacantirōtaya māttirai] is a classical tablet formulation in Siddha medicine used in various types of fevers. Because of limited research validation in terms of the produ…
Article
Formulation and Evaluation of Fast-Dissolving Oral Film of Rivaroxaban
Sandeep Kanna, Rama Rao Nadendla, Juluri Satyanarayana, Vajrala Karthikeya, Muthumula Venkata Sonu, Pusuluri Naga Bhargavi
pp. 687–695 · DOI: 10.5530/jyp.2023.15.94 · Published
Background:Following the COVID-19 pandemic, microvascular and macrovascular thrombotic problems emerged that required anticoagulants. Rivaroxaban (RN) is a factor Xa inhibitor that treats deep vein thrombosis and the two…
Article
Quality by Design and Optimization of Favipiravir Nanoparticles Using 3-Level Factorial Design by Box-Behnken Method
Vijayan Venugopal, Sakthi Ganapathi Meenachisundram, Karthikeyan Ramadoss, Nandhini Jayaprakash
pp. 696–703 · DOI: 10.5530/jyp.2023.15.95 · Published
Background:Favipiravir has a low bioavailability, a fast elimination molecule, and severe gastrointestinal side effects. The bioavailability followed by therapeutic efficacy could be improving by sustained release formul…
Article
The Effect of Marrubium vulgare on Morphine Tolerance and Withdrawal Syndrome in Male Rats
Sara Sajjadi, Rasoul Niknam, Mohammad Charkhpour, Fatemeh Fathiazad, Razie Moradi, Alireza Parvizpur
pp. 704–710 · DOI: 10.5530/jyp.2023.15.96 · Published
Background: An over-prescription of opioid analgesics triggered the opioid epidemic. Repeated opioid administrations are needed to treat chronic pain, leading to tolerance and physical dependence. Aim:Marrubium vulgare E…
Article
An Observational Prospective Study to Find Out the Incidence of Acute Kidney Injury who are Taking Non-Steroidal Anti-inflammatory Drugs
Rajesh A. Maheshwari1, Neha R. Gulati, Prem J. Prajapati, Nikunj P. Vekariya, Harshal Joshi, Rajesh Hadia, Hemraj Singh Rajput
pp. 711–715 · DOI: 10.5530/jyp.2023.15.97 · Published
Background: Acute Kidney Injury (AKI) is a common condition and can happen due to drugs like Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and which can be reversible by discontinuing NSAIDs. This research aims to exami…
Article
Efficacy and Cardiovascular Safety of Remdesivir in COVID-19: A Case-Control Study
Mageshwaran Lakshmanan, Vinothkumar Chittaranjan, Shanley-Abhishek Raju, Priya Dharshini Palanisamy
pp. 716–724 · DOI: 10.5530/jyp.2023.15.98 · Published
Background:The Food and Drug Administration (FDA) has approved remdesivir under emergency use authorization for the management of the early stage of Coronavirus Disease (COVID-19). Since remdesivir has been approved on a…
Article
Comparative Evaluation of Microhardness of Two Conventional and Hydrophilic Fissure Sealants: An in vitro Study
Ashwini K, Jayashri Prabakar, Ganesh Jeevanandan
pp. 725–729 · DOI: 10.5530/jyp.2023.15.99 · Published
Background:Dental caries are highly prevalent and if left untreated, it can lead to harmful consequences. Micro-invasive types of dental caries treatment were adopted to cease the progression of decay. Fissure sealant he…
Article
Assessment of Clinical Characteristics and Pharmacotherapy in Burning Mouth Syndrome Patients
Sreedevi Dharman, Tasleem Abitha Sahabudeen
pp. 730–733 · DOI: 10.5530/jyp.2023.15.100 · Published
Background:Burning Mouth Syndrome (BMS) is a type of persistent, debilitating orofacial discomfort that is characterized by an oral mucosal burning sensation that does not occur in the presence of any specific oral disea…
Article
A Prospective Study on Drug Audit, Prescribing Patterns Assessment, and Clinical Outcomes Evaluation in a Tertiary Care Hospital, Tamil Nadu, India
Vijayakumar S, Parimalakrishnan S, Prem Anand DC, Karthika M, Vijayakumar AR
pp. 734–742 · DOI: 10.5530/jyp.2023.15.101 · Published
Background:Research studies on drug utilization in inpatient settings serve as valuable tools for assessing drug prescribing trends, efficiency, and the cost-effectiveness of hospital formularies. Our current study focus…
Article
Drug Utilization Pattern in Chronic Kidney Disease Associated Comorbidities at a Tertiary Care Hospital
Harshita H, Neha Thakur, Jasmine Yadav, Monika M, Shreya Gupta, Inderjeet Verma
pp. 743–747 · DOI: 10.5530/jyp.2023.15.102 · Published
Background: Patients with Chronic Kidney Disease (CKD) with multiple Comorbidities like Hypertension, Diabetes, and Anemia require Numerous Drugs. Multiple drugs Predispose to Potential drug-drug Interactions, which incr…
Article
Community Pharmacists Knowledge Attitude and Practice on Rational Dispensing of Topical Corticosteroids: Pre-and Post-Intervention Study
Sowmya Spoorthi Marripalli, Madiwalayya Shivakantayya Ganachari
pp. 748–754 · DOI: 10.5530/jyp.2023.15.103 · Published
Background: Community pharmacists have an important role in dispensing topical corticosteroids only with prescription. They should be aware about the uses and the potential side effects associated with misuse of topical …
Article
A Comparative Study of Allopathy and Ayurveda Medicines in the Treatment of Type 2 Diabetes Mellitus and its Clinical Impact
Radhika Bindu, Abhay Dharamsi
pp. 755–759 · DOI: 10.5530/jyp.2023.15.104 · Published
Background:Type 2 Diabetes Mellitus (T2DM) is a complex disorder that has major health and economic consequences. Human beings have been using the herbal and allopathic systems of medicine since a long time to cure, trea…

Case Report

Article
Treatment of Localized Gingival Recession with a Modified Laterally Positioned Flap Combined with Subepithelial Connective Tissue Graft-A Case Report
Harshita Verma, Priya Lele, Vidya Dodwad, Vangmayee Shikarkhane, Niket Bhatt
pp. 760–763 · DOI: 10.5530/jyp.2023.15.105 · Published
Gingival recession, particularly in the anterior teeth, can lead to functional and aesthetic concerns. It can cause aesthetic deterioration, dentin hypersensitivity, and difficulties in maintaining proper oral hygiene. M…
Article
Modified Coronally Advanced Tunnel (MCAT) Technique with Subepithelial Connective Tissue Graft (SCTG): A Case Report
Ishani Gaikwad, Priya Lele, Vidya Dodwad, Sarah Mariam
pp. 764–766 · DOI: 10.5530/jyp.2023.15.106 · Published
Among different surgical procedures, the Modified Coronally Advanced Tunnel (MCAT) technique has been studied to increase gingival dimensions and effectively achieve coverage of the denuded root surface area and enduring…
Article
The Cardiotoxic Effects of Remdesivir Administered to the Patients with SARS-CoV Infection Dharti Bhagat1 , Sefali Patel1 , Manoj Dikkatwar2 , Radhika Bindu1
Dharti Bhagat, Sefali Patel, Manoj Dikkatwar, Radhika Bindu
pp. 767–769 · DOI: 10.5530/jyp.2023.15.107 · Published
Coronavirus has become a pandemic without a reliable treatment since December 2019. The antiviral medication remdesivir, which also inhibits one of the most powerful viral RNA enzymes, RNA dependent RNA polymerase, preve…
Article
A Rare Case Report: Wilson’s Disease
Atika Dave, Ayarin Vohra, Neha Suratiya
pp. 770–772 · DOI: JYoungPharm-15-4-770 · Published
Wilson's disease is Hepatolenticular degeneration and it is an autosomal recessive disorder. It is an uncommon genetic condition of the metabolism of copper that is predominantly brought on by alterations to the ATP7B ge…
Article
A Rare Case Report on Lagophthalmos
Khayati Gadhwal, Neha Suratiya, Trusha Prajapati, Yagni Master
pp. 773–776 · DOI: 10.5530/jyp.2023.15.109 · Published
Lagophthalmos express the imperfect palpebra closure. It can be result as feelings like there’s commodity in the eyes, Ophthalmalgia, Epiphora or dry eyes, vague vision, red eyes, scleritis, light perceptivity, Insomnole…