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Advancement and Future Window of Emulgel for Intensifying Transdermal Delivery in the Treatment of Skin Diseases

Piyali Khamkat1★, Soumen Singh2, Bramhajit Chatterjee1, Sangita Banerjee3, Siddheswar Maiti3, Sayandip Mandal1, Bikram Chowdhury1, Md Mehedi Hasan1★ Corresponding author

  1. 1Department of Pharmaceutical Technology, Brainware University, 398, Ramkrishnapur Road, Barasat, Kolkata, West Bengal, INDIA.
  2. 2Department of Pharmaceutics, Manikeswari Pharmacy School, Bhawanipatna, Kalahandi, Odisha, INDIA.
  3. 3Department of Pharmacognosy, Bengal School of Technology, Sugandha, Delhi Road, Hooghly, West Bengal, INDIA.

CORRESPONDENCE

Piyali Khamkat

Department of Pharmaceutical Technology, Brainware University, 398, Ramkrishnapur Road, Barasat, Kolkata, West Bengal, INDIA.

piyalikhamkat95@gmail.com

Received: 14-05-2025; Revised: 24-07-2025; Accepted: 02-09-2025.

Volume 17, Issue 4 · pp. 816–823 · PUBLISHED · DOI: 10.5530/jyp.20250008

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ABSTRACT

Emulgel is a blend of gel and emulsion that improves drug penetration across the epidermal barrier and facilitates efficient skin diffusion, particularly for drugs that are poorly soluble in water. It is a potent, thermodynamically robust technique that integrates co-surfactants and surfactants. The properties that emulgel includes are easily spreadable, thixotropic, transparent, greaseless, extended shelf life, detachable, emollient, and bio-friendly. These are utilized in analgesics, anti-inflammatory agents, antifungals, anti-acne products, and cosmetic compositions. This article emphasizes preparation, advancements, applications, clinical studies, and current and future aspects of emulgel for improving transdermal delivery with its regulatory challenges.

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    Khamkat, P., Singh, S., Chatterjee, B., Banerjee, S., Maiti, S., Mandal, S., Chowdhury, B., & Hasan, M. M. (). Advancement and Future Window of Emulgel for Intensifying Transdermal Delivery in the Treatment of Skin Diseases. Journal of Young Pharmacists, 17(4), 816–823. https://doi.org/10.5530/jyp.20250008