Volume 6, Issue 1

N Satheeshkumar, V Spandana, S Shantikumar, R Srinivas

pp. 1–7 · DOI: 10.5530/jyp.2014.1.1

Objective:To develop and validated a new stability indicating reverse phase high performance liquid chromatography (RPHPLC) method for analysis of naftopidil (NAF), both as a bulk drug and in formulation. Method:The sepa…

Prema Kumari Nanam, Kiran Thadkala, Chinta Sailu, Jithan Aukunuru

pp. 8–14 · DOI: 10.5530/jyp.2014.1.2

Objective:The aim of this work was to investigate and compare various practical techniques to enhance dissolution of ezetimibe, a Class II Biopharmaceutics Classifi cation System compound. Ezetimibe is a poorly soluble c…

Niti Yadav, Alka Lohani

pp. 15–21 · DOI: 10.5530/jyp.2014.1.3

Aim: The objective of the present research work was to develop stable extended release (ER) pellets of propranolol hydrochloride, an antihypertensive drug, for which drug release profi le is compared with reference to th…

Annan Sudarsan Arun Kumar, Srinivasamurthy Suresh Kumar, Gurusamy Umamaheswaran, Jayaraman Balachandar, Chandrasekaran Adithan

pp. 22–26 · DOI: 10.5530/jyp.2014.1.4

Introduction:Hypertension is a result of interaction between complex environmental and genetic factors. The genes cytochrome (CYP) 2C8, CYP2C9, and CYP2J2 are involved in the metabolism of arachidonic acid, which release…

Gowrishankar Kasilingam, Mritha ramalingam, Elanchezian Chinnavan

pp. 27–33 · DOI: 10.5530/jyp.2014.1.5

Objectives: To discuss the behavior of three different learning domains and effective assessment of each domain. Materials and Methods:Learning domains have always played an important role in evaluating the student’s kno…

Elmira Bajelan, Mohammad Kamali-nejad, Seyed Mohsen Foroutan, Hiam Albasha

pp. 34–38 · DOI: 10.5530/jyp.2014.1.6

Objective:The aim of this study was to extract the Salvia officinalis leaves, and to formulate the lozenge tablets in order to investigate a profi table dosage form. Methods:Lozenge tablets were prepared using wet granul…

Aliya Nur Hasanah, Nasrul Wathoni, Aldilla Indah Refiani, Yeni Wahyuni

pp. 39–41 · DOI: 10.5530/jyp.2014.1.7

Aim and Background: The use of polypyrrole and poly(allylamine) as a matrix of biosensor has been done separately, but the combination of this two has never existed. The purpose of this research is to produce a selective…

Begoña Ruiz-Núñez, Gert E Schuitemaker, DA Janneke Dijck-Brouwer, Frits AJ Muskiet

pp. 42–45 · DOI: 10.5530/jyp.2014.1.8

Aim and Background: Astaxanthin is a unique carotenoid of predominantly marine origin providing the pink-red color to certain microalgae and accumul ating in various animals higher in the food chain. It is an antioxidant…