Volume 5, Issue 4

Biswajit B

pp. 111 · DOI: 10.1016/j.jyp.2014.01.001

The age adjusted incidence rate of childhood cancer in India is 38e124 per million children per year. The most common malignancies in childhood include Leukaemia, Lymphoma and Brain tumours.1 The 5 year overall survival …

Mageshwaran Lakshmanan, Alphienes Stanley Xavier

pp. 112–115 · DOI: 10.1016/j.jyp.2013.12.002

Increasing incidence of MDR-TB, long duration of treatment and co-infection with HIV are the significant problems in achieving the eradication of tuberculosis. Bedaquiline is an anti-tuberculosis drug with unique mechani…

Manjunath Ajanal, Shradda Nayak, Buduru Sreenivasa Prasad, Avinash Kadam

pp. 116–120 · DOI: 10.1016/j.jyp.2013.10.001

Drug safety is a very basic and fundamental concept in medical practice. ADRs play an important role in assessing patient safety in any system of medicine. Pharmacovigilance study is thus significant to understand treatm…

Kothagorla Venkata Raghava Rao, Tamanam Raghava Rao

pp. 121–126 · DOI: 10.1016/j.jyp.2013.10.002

Objective: To isolate and identify the biologically active strain of Streptomyces species from mangrove soil of Visakhapatnam region. Materials and methods: Actinomycetes are isolated by using starch casein agar media an…

Pavan Kommavarapu, Arthanareeswari Maruthapillai, Ravikiran Allada, Kamaraj Palanisamy, Praveen Chappa

pp. 127–132 · DOI: 10.1016/j.jyp.2013.10.003

Objective: In the present study, simultaneous determination of degree of crystallinity content in abacavir (ABC), lamivudine (3TC) and neverapine (NVP) from there combination drug product using X-ray powder diffraction (…

Om Prakash Ranjan, Usha Y. Nayak, Meka Sreenivasa Reddy, Swapnil J. Dengale, Prashant B. Musmade, Nayanabhirama Udupa

pp. 133–138 · DOI: 10.1016/j.jyp.2013.10.006

Objective: To develop a liquid–liquid extraction based reverse phase liquid chromatography method for estimation of montelukast in rabbit plasma. Methods: Chromatographic separation was carried out using Phenomenex Luna …

Sunita Shailajan, Priyanka Wadke, Harshvardhan Joshi, Bhavesh Tiwari

pp. 139–143 · DOI: 10.1016/j.jyp.2013.10.005

Background:Infestation with the head louse, Pediculus humanus capitis, is one of the most common parasitic infestations of human worldwide. Traditionally, the main treatment for control of head lice is chemical control t…

Sirajudeen S. Alavudeen, C.K. Dhanapal, Noohu Abdulla Khan, Khalid M. Al Akhali, Sam Daniel Paulliah

pp. 144–147 · DOI: 10.1016/j.jyp.2013.11.006

Background/Aim: Dyslipidemia is a significant predictor of cardiovascular events and mortality in diabetes patients. The aim of this study is to estimate the prevalence rates, characteristics of dyslipidemia and their co…

Sumanta Kumar Goswami, Mohammed Naseeruddin Inamdar, Rohitash Jamwal, Shekhar Dethe

pp. 148–153 · DOI: 10.1016/j.jyp.2013.11.001

Objective:Cinnamomum cassia has been suggested in Ayurveda for the management of sexual dysfunction. This research work was conducted to shed some light on the mechanism of action of the extract, and evaluate the efficac…

Sekar Vinoth Kumar, Mohan Raj Subramanian, Santhosh Kumar Chinnaiyan

pp. 154–159 · DOI: 10.1016/j.jyp.2013.11.004

Rationale:Benzimidazoles and its derivatives represent one of the mainly biological active classes of literature. Aim:In this present study aimed to synthesize N-mannich bases derivatives compounds bearing of 2-substitut…

Sonia Pandey, Ashish Mishra, Pooja Raval, Hetal Patel, Arti Gupta, Dinesh Shah

pp. 160–166 · DOI: 10.1016/j.jyp.2013.11.002

Objective:The objective of present work was to prepare a polyelectrolyte complex (PEC) between chitosan (polycation) & pectin (polyanion) and to develop enteric coated tablets for colon delivery using the PEC. Methodolog…

Pushkar R. Sharma, Shaila A. Lewis

pp. 167–172 · DOI: 10.1016/j.jyp.2013.11.003

Aim:Nateglinide is a quick acting anti-diabetic medication whose potent activity lasts for a short duration. One of the dangerous side effects of nateglinide administration is rapid hypoglycemia, a condition that needs t…

Md. Rezaul Islam, Aubhishek Zaman, Iffat Jahan, Rajib Chakravorty

pp. 173–179 · DOI: 10.1016/j.jyp.2013.11.005

Acetylcholine-esterase (AchE) inhibitors are one of the most potent drug molecules against Alzheimer’s disease (AD). But, patients treated with current AchE inhibitors often experience severe side effects. Quercetin is a…

Arti Gupta, Navin R. Sheth, Sonia Pandey, Dinesh R. Shah, Jitendra S. Yadav

pp. 180–187 · DOI: 10.1016/j.jyp.2013.12.003

Aim: To isolate and identify the quercetin from polyherbal hepatoprotective formulation. Polyherbal formulations were developed by using five bioactive fractionated extracts of Butea monosperma, Bauhinia variegata and Oc…

Teógenes M. Souza, Maria F.B. Morais-Braga, José G.M. Costa, Antônio A.F. Saraiva, Micheline A. Lima, Henrique D.M. Coutinho

pp. 188–190 · DOI: 10.1016/j.jyp.2013.10.004

Aims: In this work, the ethyl acetate and hexane fractions of Pityrogramma calomelanos (L.) were evaluated to antibacterial and antifungal activity against strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococ…

Jagdish Manwar, Kakasaheb Mahadik, Anant Paradkar, Lohidasan Sathiyanarayanan, Mustafa Vohra, Sanjay Patil

pp. 191–194 · DOI: 10.1016/j.jyp.2013.11.007

Objective:To isolate and characterize the alcohol-producing yeasts from Woodfordia fruticosa flowers, which are used for the induction and maintenance of fermentation in the making of Ayurvedic formulations. Materials an…

Selvaraj Nitya, Kameswari Deepa, Adhimoolam Mangaiarkkarasi, Kaliaperumal Karthikeyan

pp. 195–196 · DOI: 10.1016/j.jyp.2013.12.001

Adverse drug reactions are a major hazard of modern medicine. Fixed drug eruption, which is a cutaneous adverse drug reaction, is commonly seen with antimicrobials and analgesics. Here we report 37- year-old female with …