Volume 1, Issue 2

· pp. 99–189 · 16 articles

In this issue

Article
Pharmaceutical E-Learning: Precepts, Retrospect and Prospects
Singh B, Kapil R, Katare OP
pp. 99–109 · DOI: 10.4103/0975-1483.55740 · Published
The domain of pharmaceutical sciences is a highly dynamic one with the half-life of pharmaceutical information declining constantly. Be it the drug industry or the academic institutes, it is mandatory to keep abreast w…

Article
Skin Penetration Enhancement Techniques
Bharkatiya M, Nema RK
pp. 110–115 · DOI: 10.4103/0975-1483.55741 · Published
Transdermal drug delivery systems allow delivery of a drug into the systemic circulation via permeation through skin layers at a controlled rate. In addition to the currently marketed formulations, new drugs are being fo…
Article
Formulation and Evaluation of Drug-free Ophthalmic Films Prepared by Using Various Synthetic Polymers
Patel Dipti H, Patel Manish P, Patel Madhabhai M
pp. 116–120 · DOI: 10.4103/0975-1483.55742 · Published
An attempt has been made to formulate drug-free ophthalmic Þ lms by using different polymers in single use as well as in combinations for matrix system design for ocular use and to study the effect of various plasticizer…
Article
Preparation of Biodegradable Microspheres Containing Repaglinide
Tamizharasi S, Jagdish Chandra R, Vaishali R
pp. 121–124 · DOI: 10.4103/0975-1483.55743 · Published
The objective of the present study is to prepare and evaluate poly(ε-caprolactone) microspheres of repaglinide by using the solvent evaporation technique. The microspheres were prepared with different drug-to-carrier rat…

Article
Anti-Infl ammatory Activity of Ethanolic Leaf Extracts from Adenanthera pavonina (L) in Rats
Mayuren C, Ilavarasan R
pp. 125–128 · DOI: 10.4103/0975-1483.55744 · Published
Ethanolic extracts from the leaves of Adenanthera pavonina were assessed at doses of 250 and 500 mg/kg for anti-inß ammatory effects using both acute and chronic inß ammatory models. The anti-diarrheal activity was also …
Article
Free-Radical–Scavenging Activity in the Infl orescence of European Nettle/Sisnu (Urtica dioica L.)
Mandal P, Misra TK, Singh ID, Das JK, Bhunia M
pp. 129–135 · DOI: 10.4103/0975-1483.55745 · Published
The inß orescence of Urtica dioica L. is used by ethnic people of Darjeeling Hills as therapeutics and green vegetables. As it is ethnomedicinally very important for curing several critical and emerging oxidative stress…
Article
Comparative Evaluation of Extracts of Citrus limon Burm Peel for Antioxidant Activity
Akhila S, Bindu AR, Bindu K, Aleykutty NA
pp. 136–140 · DOI: 10.4103/0975-1483.55746 · Published
Cellular damage arising from free radicals is one of the fundamental mechanisms underlying a number of human neurodegenerative disorders like diabetes, inß ammation, Alzheimers disease, autoimmune pathologies, and diges…

Article
Pharmacology of Recombinant or Genetically Engineered Drugs
Kamal Kishore, Pawan Krishan
pp. 141–150 · DOI: 10.4103/0975-1483.55747 · Published
Recombinant technology or genetic engineering is a modern method used for the synthesis of therapeutic agents. The central theme of recombinant technology is the process of gene cloning which consists of the production…
Article
Diabetes Type-II Exaggerates Renal Ischemia Reperfusion Injury by Elevation of Oxidative Stress and Infl ammatory Response
Vaghasiya J, Sheth N, Bhalodia Y, Jivani N
pp. 151–159 · DOI: 10.4103/0975-1483.55748 · Published
Objective:The present work was designed to investigate the role of Diabetes Mellitus Type-II (DM-II) on renal ischemia reperfusion (I/R)-associated pathophysiology in renal damage. Materials and Methods:DM-II in rats was…
Article
Glucose-lowering, Hepatoprotective and Hypolipidemic Activities of Stem Bark of Ficus racemosa in Streptozotocin-Induced Diabetic Rats
Ahmed F, Urooj A
pp. 160–164 · DOI: 10.4103/0975-1483.55749 · Published
The present study evaluated the antihyperglycemic, hepatoprotective, and hypolipidemic effects of F. racemosa bark powder and aqueous extract in streptozotocin-induced diabetic rats. Streptozotocin-induced diabetic rats …

Article
Synthesis and Characterization of Pyrazine-2-Carbohydrazide Derivatives as Antimicrobial Agents
Miniyar PB, Makhija SJ
pp. 165–169 · DOI: 10.4103/0975-1483.55750 · Published
A series of pyrazine-2-carbohydrazide derivatives has been synthesized and assessed for their in vitro antimicrobial activity against Gram-positive and Gram-negative strains of bacteria. In the present study, pyrazinamid…
Article
Synthesis and Screening for Analgesic and Anti-infl ammatory Activities of Some Novel Amino Acid-containing Bicyclo Compounds
Sharma CS, Nema RK, Sharma VK
pp. 170–174 · DOI: 10.4103/0975-1483.55751 · Published
Diazabicyclo[4.3.1]decane derivatives are well known opioid receptor ligands, hence, we have developed a novel and simple method for the synthesis of 3, 4-diphenyl-2,5-diaza-bicyclo[4.3.1]deca-1(9),2,4,6(10),7-pentaene- …

Article
Quantitative Analysis of Manidipine Dihydrochloride in Bulk and Synthetic Mixtures by Visible Spectrophotometry
Lakshmi Sivasubramanian, Manikandan K, Venkatesan M, Lakshmi KS
pp. 175–179 · DOI: 10.4103/0975-1483.55752 · Published
The present work describes three visible spectrophotometric methods for the quantitative estimation of Manidipine in bulk and synthetic mixtures. Method A is based on the reaction of the drug with para-dimethylaminobenza…

Article
Drug Utilization and Prescription Monitoring of Asthma Patients
Vijaya Kumar S, Sasi Kala M, Mohamed Saleem TS, Gauthaman K
pp. 180–183 · DOI: 10.4103/0975-1483.55753 · Published
The present study was conducted to establish prescription trends of anti-asthmatic drugs at the Central Referral Hospital, Tadong and Gangtok, Sikkim. The study was conducted using WHO-based prescriptionauditing performa…
Article
Relevance of the use of Alternative Medicine for Bronchial Asthma: A review
Sasi Kala M, Vijaya Kumar S, Gauthaman K
pp. 184–189 · DOI: 10.4103/0975-1483.55754 · Published
Alternative systems of medicine include Chinese medicine, Ayurveda, homeopathic, and naturopathic medicine. Chinese medicine emphasizes the balance of qi (chee) or vital energy. Within this system, illness is deÞ ned a…

Article
Topics in the History of Pharmacology
Chetna Patel
pp. 190 · DOI: · Published
Reviewing a book is really a difÞ cult job, especially when it is written by people who themselves are masters in a particular Þ eld. I am only trying to contribute a little by giving important and useful information abo…