Volume 12, Issue 2S

Original Artcile

1. Article

   Synthesis, Characterization, Antitubercular Activity and Docking Studies of 2-(benzo [d]oxazol-2-ylthio)-1-(3-(4-fluoro-3- methylphenyl)-5-(substituted aryl)-4,5-dihydro-1H-pyrazol-1-yl) ethanone

   Muralidharan Venugopal, Raja Sundararajan, Asha Deepti Choppala

   pp. s1–s9 · DOI: 10.5530/jyp.2020.12s.39 · Published

   A new series of 2-(benzo[d]oxazol-2-ylthio)-1-(3-(4-fluoro-3-methylphenyl)-5- (substituted aryl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone (6a-6j) were designed and synthesized from the intermediate chalcones (1a-1j). The syn…

2. Article

   Nano Co-crystal Engineering Technique to Enhance the Solubility of Ezetimibe

   Jyothi Bhandari, Neha Kanswami, Lakshmi P.K

   pp. s10–s15 · DOI: 10.5530/jyp.2020.12s.40 · Published

   Background:Co-crystals have been highly promising for tailoring physicochemical properties of Active pharmaceutical ingredient (API) by coupling with co-former. Objectives: The objective of the present work was to prepar…

3. Article

   Design and Characterization of Bilayered Floating Tablets of Clopidogrel Bisulfate and Aspirin using Natural Gums

   Manasa Reddy Devarapalli, Latha Kukati Latha, Naseeb Basha Shaik, Shailaja Thoudoju, Saleha Fatima, Arshiya Sheerin, Mohammed Atif Mujtaba, Shashanka Bhukya, Gaikwad Sushmitha

   pp. s16–s24 · DOI: 10.5530/jyp.2020.12s.41 · Published

   Objectives:In present investigation, an attempt was made to develop bilayered floating tablets of clopidogrel bisulfate and aspirin using natural gums as release retarded material. Clopidogrel bisulfate and aspirin are a…

4. Article

   Formulation and Characterization of Amisulpride Microemulsions for Brain Targeting via Intranasal Route-Pharmacodynamic Evaluation in Rat Model

   Abilash Teja Ganta, Ravikrishna Velupula, Krishnaveni Janapareddi

   pp. s25–s31 · DOI: 10.5530/jyp.2020.12s.42 · Published

   Amisulpride is an atypical antipsychotic drug with dopamine (D2 /D3 ) receptor blocker activity. The oral bioavailability of amisulpride was below 48% due to first pass metabolism and poor aqueous solubility. In order to…

5. Article

   Formulation and Evaluation of Floating Polymeric Nanoparticles of Linagliptin in Capsules

   D. Prasanthi, J. Krishna Kumari, S. Hymavathi

   pp. s32–s38 · DOI: 10.5530/jyp.2020.12s.43 · Published

   Objectives:Linagliptin is a BCS class III drug used in treatment of diabetes. In the present study floating polymeric nanoparticles of linagliptin are formulated to increase the residence time of drug in stomach by contr…

6. Article

   Formulation and Evaluation of Extended Release Matrix Tablets of Tenatoprazole Sodium using Synthetic Polymers

   B. Divya, J. Sreekanth, D. Satyavati

   pp. s39–s44 · DOI: 10.5530/jyp.2020.12s.44 · Published

   Extended release formulations are designed to release their medication in a controlled manner at a predetermined rate, duration and location to achieve and maintain optimum therapeutic blood levels of a drug. The present…

7. Article

   Formulation and Evaluation of Zidovudine Transdermal Patch using Permeation Enhancers

   Jajala Mamatha, Sravya Gadili, Kanagala Pallavi

   pp. s45–s50 · DOI: 10.5530/jyp.2020.12s.45 · Published

   Objective:The objective of this research was to study the permeation of zidovudine using permeation enhancers. Methodology:Transdermal patches were formulated using permeation enhancer namely T-Anethole. Zidovudine patch…

8. Article

   Development and Validation of Chemometric Assisted FTIR Spectroscopic Method for Simultaneous Estimation of Valsartan and Hydrochlorothiazide in Pure and Pharmaceutical Dosage Forms

   Adiba Rahman, Garige Jaya Sravani, Kuntala Srividya, Anand Das Ramesh Priyadharshni, Avireni Narmada, Kurapati Sahithi, Talagadadeevi Krishna Sai, Yenumula Padmavathi

   pp. s51–s55 · DOI: 10.5530/jyp.2020.12s.46 · Published

   Objectives:To develop a new Chemometric assisted Fourier transform infrared (FTIR) spectroscopic method for the simultaneous estimation of valsartan and hydrochlorothiazide in pharmaceutical dosage forms. Methods:The met…

9. Article

   Development and Characterization of Levodopa Loaded Pharmacosomes for Brain Targeting via Intranasal Route: Pharmacodynamic Evaluation in Rats

   Yashaswini Kotha, Anil Goud Kandhula, Krishnaveni Janapareddi

   pp. s56–s62 · DOI: 10.5530/jyp.2020.12s.47 · Published

   Parkinson’s is the second most common progressive neurodegenerative disease and affects 1-2% people over the age 50. Levodopa is the drug of choice in the treatment of Parkinson’s disease and exhibits low oral bioavailab…

10. Article

    Method Development, Validation and Forced Degradation Studies for Determination of Tigecycline in Bulk and Pharmaceutical Dosage Form using UV Spectroscopy

    Khagga Bhavyasri, Chejati Mounika, M Sumakanth

    pp. s63–s66 · DOI: 10.5530/jyp.2020.12s.48 · Published

    Objective:The present research work aimed to develop and validate a simple, rapid, accurate and reproducible UV Spectroscopic method for the quantitative estimation of Tigecycline in bulk and pharmaceutical dosage form. …

11. Article

    Isolation, Characterization and Assessment for Muscle Relaxant Activity of Novel Phytomolecule from Galphimia glauca Cav. Stems

    Baba Shankar Rao Garige, Dugur Prasanna Laxmi, Donthuri Akhila Sravani, Jillella Rachana, Gaddam Shirisha, Ram Mohan Manda, Vasudha Bakshi

    pp. s67–s71 · DOI: 10.5530/jyp.2020.12s.49 · Published

    Objectives:Galphimia glauca Cav (Gg) is an evergreen medicinal herb found growing in Indian subcontinent and more in the Deccan plateau regions of south India. The objective of the current work is to isolate, characteriz…

12. Article

    In vitro Studies on α-Amylase and α-Glucosidase Inhibitory Activity of Some Bioactive Extracts

    Sayyada Saleha Momina, Vanapatla Swaroopa Rani

    pp. s72–s75 · DOI: 10.5530/jyp.2020.12s.50 · Published

    Objectives: To investigate the therapeutic effects of methanolic leaf extracts of Lindernia ciliata, Phyllanthus reticulatus and Bambusa vulgaris were evaluated for their effect on α-amylase and α-glucosidase inhibition …

13. Article

    Assessment of Antiurolithiatic Potentials of Crinum asiaticum Bulbs by in vitro and in vivo Approaches

    Suman Sura, Venkata Suresh Kumar Solleti

    pp. s76–s81 · DOI: 10.5530/jyp.2020.12s.51 · Published

    Objectives:To evaluate the antiurolithiatic potential of Crinum asiaticum through in vitro and in vivo methods. Materials and Methods: Ethanolic extract of Crinum asiaticum (EECA) subjected for phytochemical screening an…

14. Article

    Neuropsychological Screening on Acalypha indica Whole Plant Extract

    N.V.L Suvarchala Reddy V, Ganga Raju M, Sirisha S, Nikitha K

    pp. s82–s86 · DOI: 10.5530/jyp.2020.12s.52 · Published

    Objectives:Herbal treatment is a natural form of healing or alternative therapy to cure ailments or diseases of cognitive disorders. Methods:The methanolic whole plant extract of Acalypha indica was screened for its Anti…

15. Article

    Neuroprotective Activity of Methanolic extract of Terminala bellerica Fruit against Aluminium Chloride and Haloperidol Induced Amnesia in Mice

    N V L Suvarchala Reddy V, Ganga Raju M, Rahul Goud M, Shabnamkumari T

    pp. s87–s90 · DOI: 10.5530/jyp.2020.12s.53 · Published

    Objectives:The data presented in the article is related to evaluation of Terminalia bellerica fruits methanol extract (METB) for the neurodegenerative disorders along with their antioxidant potential. Methods:Various phy…

16. Article

    Anti-Amnesic Effect of Methanolic Leaf Extract of Tecoma stans: An Experimental Study in Rodents

    Ganga Raju M, Gouthami K, N V L Suvarchala Reddy V, Michaela Nicholas

    pp. s91–s96 · DOI: 10.5530/jyp.2020.12s.54 · Published

    Objectives:Herbal therapy is a natural practice of curative or substitute remedy to treat disorders or illnesses aimed at the management of cognitive ailments. Memory loss is a shortfall in recollection triggered by brai…

17. Article

    Evaluation of Antibiotics use in Orthopedic Procedures

    Shubham Babu Gupta, Pankaj Wadhwa

    pp. s97–s101 · DOI: 10.5530/jyp.2020.12s.55 · Published

    Background:Appropriate utilization of antimicrobial specialists is imperatively significant from clinical points. Present anti-microbial agents are one of very crucial for clinical consideration and assume a significant …

18. Article

    Assessment of Rational use of Antibiotics in Orthopedic Surgery Procedures

    T. Veena Priyanka Anand, S. Kavya Sree, S. Pavani, G. Manju Bhargavi, Shubham Babu Gupta

    pp. s102–s107 · DOI: 10.5530/jyp.2020.12s.56 · Published

    Introduction:Appropriate use of antimicrobial agents is important and is essential if the usefulness of antibiotic is to be preserved and the further spread of resistance is to be limited. Antibiotics are one of the pill…

19. Article

    Epidemiological Study of Risk Factors in Myocardial Infarction Patients

    Konda Sushritha, Anju Sharma, Konda Suman, Palakurthy Harish Goud, Sadanandamn Akari

    pp. s108–S112 · DOI: 10.5530/jyp.2020.12s.57 · Published

    Introduction:Recent ecological study for major CVD risk factors and mortality indicates a high correlation between expected and observed mortality rates for three major risk factors- hypertension, diabetes, smoking. Surv…

20. Article

    Development and Validation of Microbiological Analytical Method for Determination of Potency of Voriconazole Tablets

    Mami Sahitya, Sana Fathima, Ancha Divya, Kyadari Vaishali, Meshkhana NidhiSree, Challoori Spandana Reddy, Toleti Sree Ramya, Sandhya Rani, Yenumula Padmavathi, Ravi Kiran

    pp. s113–s116 · DOI: 10.5530/jyp.2020.12s.58 · Published

    A new microbiological method was developed for analysis of voriconazole tablets using Candida albicans as test microorganism. Various media, species and conditions were used to optimize the diffusion test. A prospective …