Journal of Young Pharmacists
Volume 9, Issue 4
· pp. 451–619 · 29 articles
- Volume
- 9
- Issue
- 4
- Published
- Pages
- 451–619
- Articles
- 29
- Sections
- 4
- ISSN
- Print - 0975-1483 | Online - 0975-1505
- Journal
- JYP
In this issue
Editorial
- Forum Article
Antibiotics Risk of Obesity in Children: Major Threats in Health care System
Chidambaram Ramasamy, Subramani Parusuraman
pp. 451–452 · DOI: 10.5530/jyp.2017.9.88 · Published
One of the health related topics, which is consistently receiving attention in recent years, is antibiotic misuse. Interestingly, there is a high-profile report claiming that antibiotic consumption could trigger obesity …
Review Article
- Review
Dental Management of the Cardiovascular Compromised Patient: A Clinical Approach
Saurabh Singh, Khushboo Gupta, Kavita Nitish Garg, Neeraj Kumar Fuloria, Shivkanya Fuloria, Teerthesh Jain
pp. 453–456 · DOI: 10.5530/jyp.2017.9.89 · Published
Cardiovascular disease trends, complications, and associated therapeutics, impact the dental health and treatment. Such patients require special consideration with regard to when and which dental treatment is appropriate…
Original Artcile
- Article
Optimization of Ionic Liquid-Based Microwave Assisted Extraction to Obtain Trans-resveratrol from Gnetum gnemon L. Seeds
Imalia Nurachma Ayuningtyas, Maesya Rahmawati, Sutriyo s, Abdul Mun’im
pp. 457–462 · DOI: 10.5530/jyp.2017.9.90 · Published
Introduction: Gnetum gnemon L. (Melinjo) is popular in Indonesia as a source of nutrition. Its seeds contain trans-resveratrol, which has been shown to have multiple pharmacological activities. The application of ionic l…
- Article
The Antifungal Effect of some 4-Chloro-6-Methoxy-N, N-Dimethylpyrimidin-2-Amine Derivatives Containing a Heterocyclic Compound on the Important types of Fungi
Nadhir N.A. Jafar, Ibtihial M Abdul Mahdi, Mahmoud Hussein Hadwan, Ameer A, Alameri
pp. 463–467 · DOI: 10.5530/jyp.2017.9.91 · Published
Objective: 4-methoxy-N, N-dimethyl-6-(phenylthio) pyrimidin-2-amine, 4-(benzo[d]thiazol-2-ylthio)-6-methoxy-N,N-dimethylpyrimidin-2-amine, 4-(4-(1,2,3-selenadiazol-4-yl)phenoxy)-6-methoxy-N,N 2-amine and 4-(4-(1,2,3-thia…
- Article
Antifungal Effect of Kaffir Lime Leaf Extract on Selected Fungal Species of Pathogenic Otomycosis in in vitro Culture Medium
Mohd Syafwan Soffian, Irfan Mohamad, Zeehaida Mohamed, Rosdan Salim
pp. 468–474 · DOI: 10.5530/jyp.2017.9.92 · Published
Background: Kaffir lime (Citrus hystrix D.C) has been used for a long time in agricultural and alternative medicine. Kaffir lime leaf (KLL) had been proved effective against certain fungi that could infect human body. Ob…
- Article
Computational Study of Bufadienolides from Indonesia’s Kalanchoe pinnata as Na+/K+-ATPase Inhibitor for Anticancer Agent
Muhammad Yusuf, Ade Rizqi Ridwan Firdaus, Unang Supratman
pp. 475–479 · DOI: 10.5530/jyp.2017.9.93 · Published
Objectives: This study aimed to predict the binding pose of bufadienolides from Kalanchoe pinnata on Na+/K+-ATPase using molecular docking in comparison with a known inhibitor, and to determine the important functional g…
- Article
Comparative insilico Docking Analysis of Curcumin and Resveratrol on Breast Cancer Proteins and their Synergistic Effect on MCF-7 Cell Line
Rathinasabapathy Pushpalatha, Subramanian Selvamuthukumar, Duraisamy Kilimozhi
pp. 480–485 · DOI: 10.5530/jyp.2017.9.94 · Published
Object: To compare the molecular activity of curcumin and resveratrol on selected breast cancer protein receptors and to investigate their combination for synergism against human breast cancer MCF-7 cell line. Method: Cu…
- Article
Application of Ionic Liquid as a Green Solvent for Polyphenolics Content Extraction of Peperomia pellucida (L) Kunth Herb
Islamudin Ahmad, Arry Yanuar, Kamarza Mulia, Abdul Mun’im
pp. 486–490 · DOI: 10.5530/jyp.2017.9.95 · Published
Objective: The aims of the study was to explore the application effect of ionic liquid as a green solvent in the polyphenolics content extraction from Peperomia pellucida (L.) Kunth herbs using 1-butyl-3-methyl imidazoli…
- Article
Impacts of Nitrogen Starvation on Expression Profiles of Involving Genes in Triacylglycerol Biosynthesis in Chlamydomonas reinhardtii: Towards Microalgal Systems Biotechnology
Mohammad Hossein Morowvat, Younes Ghasemi
pp. 496–501 · DOI: 10.5530/jyp.2017.9.97 · Published
Objective: Chlamydomonas reinhardtii, the most commonly studied model organism in microalgal kingdom, is known to be a rich lipid producer. Methods: Here, a naturally isolated C. reinhardtii strain was cultivated phototr…
- Article
Investigation of Oligosaccharides for Prebitoic Action on Vaginal Lactobacilli
Jayashri Gajananrao Mahore, Bhavana Bhikhubai Rohit, Sanjeevani Shekhar Deshkar
pp. 502–506 · DOI: 10.5530/jyp.2017.9.98 · Published
Objective: Vaginitis is a very common gynaecological problem in women of all age groups resulted in millions of visit to physician. Decrease in vaginal Lactobacilli is one of the reasons of Bacterial vaginitis. Approach …
- Article
Enhancement of Percutaneous Delivery of Dapsone by Microemulsion Gel
Jayashri Gajananarao Mahore, Suvarna Dinkarrao Suryawanshi, Satish Vasudeo Shirolkar, Sanjeevani Shekhar Deshkar
pp. 507–512 · DOI: 10.5530/jyp.2017.9.99 · Published
Objective: The purpose of this study was to developed microemulsion based gel formulation for topical delivery of dapsone with an objective to increase the solubility and skin permeability of the drug for treatment of ac…
- Article
Formulation Optimization and Study on Effect of Penetration Enhancers on Reservoir Transdermal Therapeutic Systems of Hydralazine Hydrochloride
Revathi Mannam, Indira Muzib Yallamalli
pp. 513–518 · DOI: 10.5530/jyp.2017.9.100 · Published
Background: Hydralazine hydrochloride (HZH) is a drug candidate used to treat pulmonary arterial hypertension. Extreme variability in oral dosing, bioavailability of 31%, variable half-life of 3 to 7 h and molecular weig…
- Article
Design and Evaluation of Ondansetron Fast Disintegrating Tablets Using Natural Polymers and Modified Starches as Super Disintegrants for the Enhancement of Dissolution
Sravanthi Mulagada, Srinivasa Rao Baratam
pp. 519–524 · DOI: 10.5530/jyp.2017.9.101 · Published
Objective: Ondansetron is an anti-emetic drug which is insoluble in water; hence the drug may be slowly or incompletely dissolves in the gastrointestinal tract. So the rate of dissolution and therefore its bioavailabilit…
- Article
Enteric Delivery of Diclofenac Sodium through Functionally Modified Poly(acrylamide-grafted-Ghatti gum)-based pH-sensitive Hydrogel Beads: Development, Formulation and Evaluation
Afrasim Moin, Talib Hussain, DV Gowda
pp. 525–536 · DOI: 10.5530/jyp.2017.9.102 · Published
Background: To prepare and characterize modified Poly(acrylamide-grafted- Ghatti gum). To formulate and evaluate using this grafted polymer pH-sensitive hydrogel beads of diclofenac sodium for enteric delivery. Methods: …
- Article
In vitro Anti-Cancer Activity of Rosuvastatin and Ketorolac Nanoformulations against DDX3
Khaggeswar Bheemanapally, Manish Kumar Thimmaraju, Sagar Kasagoni, Prathyusha Thatikonda, Swathi Akula, Kranthi Raj Kodamala, Lavanya Kakarla, Sridhar Babu Gummadi, Harishankar Nemani, Mahendran Botlagunta
pp. 537–544 · DOI: 10.5530/jyp.2017.9.103 · Published
Background: DDX3 is the human RNA helicase and enhanced expression of DDX3 protein was found in several cancers including leukemia. Statin family of drugs shown to inhibit the growth of acute myeloid leukemia cells. Obje…
- Article
Effect of Ethanolic Extract Fractions of Boerhaavia diffusa in Doxorubicin-induced Myocardial Toxicity in Albino Rats
Shrishail Kashinath Nimbal, Basavaraj Chanabasappa Koti
pp. 545–549 · DOI: 10.5530/jyp.2017.9.104 · Published
Background: Doxorubicin is a Anthracycline derivative and has proven efficacy in various malignancies. It is the most effective cytotoxic agent in current use. The clinical usefulness is limited due to its cardiac toxici…
- Article
Beneficial Effects of Tephrosia purpurea Ethanolic Seed Extract on Lipids and Membrane Bound Enzymes in Experimental Diabetic Rats
Pavana Pamu, Manoharan Shanmugam, Sethupathy Subramanian
pp. 550–554 · DOI: 10.5530/jyp.2017.9.105 · Published
Objective: Traditionally, Tephrosia purpurea Linn. (Fabaceae) is known to possess medicinal values in treating diabetes and other endocrine disorders. In this experiment, authors evaluated the beneficial role of Tephrosi…
- Article
Enrichment of the Gamma Oryzanol Level from Rice Bran by Addition of Inorganic Salts on Ionic Liquid 1-Butyl-3- Methylimidazolium Hexafluorophosphate ([BMIM] PF6 ) Extraction
Elsa Trinovita, Sutriyo s, Fadlina Chany Saputri, Abdul Mun’im
pp. 555–558 · DOI: 10.5530/jyp.2017.9.106 · Published
Objective: Rice bran oil has many helath benefit. The biologically active compounds of rice bran oil are fatty acids, squalene, tocopherols, phytosterols, tocotrienols, oryzanol, and polyphenols. Gamma oryzanol is a comb…
- Article
HMG-CoA Reductase Inhibitory Activity of Gnetum gnemon Seed Extract and Identification of Potential Inhibitors for Lowering Cholesterol Level
Kholid Abdul Hafidz, Nuraini Puspitasari
pp. 559–565 · DOI: 10.5530/jyp.2017.9.107 · Published
Objectives: Melinjo (Gnetum gnemon) seeds have been known to have some biological properties. One of them is ant hypercholesterolemia. The present study investigated in vitro and in silico methods to predict potential an…
- Article
Effect of Solanum nigrum Linn on Acute and Sub-Acute Models of Inflammation
Ankalikar Aryaa, Agadi Hiremath Viswanathswamy
pp. 566–570 · DOI: 10.5530/jyp.2017.9.108 · Published
Objective: The aim of the study was to see the effect of ethanolic extract of Solanum nigrum Linnon Acute and Sub-acute inflammation. Method: Wistar rats weighing 150-200gms were used, divided into four groups Group 1 wa…
- Article
Supply Chain Management of Antiretroviral Drugs in Public Health Facilities in Eastern Ethiopia
Tesfaye Gabriel, Tadesse Bekele Tafesse
pp. 571–576 · DOI: 10.5530/jyp.2017.9.109 · Published
Objective: Present study is aimed at assessing the supply chain management (SCM) of drugs in selected public health facilities in Dire Dawa City Administration, Harari Region and Jigjiga Zone in Somali Region, Eastern Et…
- Article
A Study on Herbal Drugs Utilization in Health Care Professionals (Physicians/Academicians)
Nabila Perveen, Naeem Hasan Khan, Azmi Sarrif
pp. 577–582 · DOI: 10.5530/jyp.2017.9.110 · Published
Objective: To investigate the herbal drugs utilization by healthcare professional (physician/academician) at AIMST University, Kedah D.A., and Malaysia. Method: Analysis was carried out by using a Software Package for St…
- Article
The Extent and Factors Associated with Non-Prescription Medicine Use in Eastern India – A Cross-Sectional Survey
Manisha Das, Supriyo Choudhury, Ranjita Santra (Dhali), Rituparna De, Ranendra Kumar Roy
pp. 583–587 · DOI: 10.5530/jyp.2017.9.111 · Published
Objective: To assess the extent, pattern and determinants of non-prescription medicine use in an urban area of eastern India. Methods: A descriptive cross-sectional survey with total 392 subjects was carried out for 3 mo…
- Article
Effectiveness of an Interventional Educational Tool on Certain Overweight and Obesity Parameters Among the General Public in Sungai Petani, Kedah Darul Aman, Malaysia
Sam Aaseer Thamby, Azmi Bin Sarrif, Ng Yen Ping, Dayana Nicholas, Balasubramanian Ganesh Pandian, Sireesha Paruchuri
pp. 588–592 · DOI: 10.5530/jyp.2017.9.112 · Published
Background: Overweight and obesity prevalence are increasing in Malaysia. This epidemic has affected a very high number of children and young adults. This poses a serious health hazard, not only presently, but also for t…
- Article
Chemotherapy Induced Adverse Drug Reactions in Cancer Patients in a Tertiary Care Hospital in South India
Sapan Kumar Behera, Chenchu Reddy Kishtapati, Vikneswaran Gunaseelan, Biswajit Dubashi, Adithan Chandrasekaran, Sandhiya Selvarajan
pp. 593–597 · DOI: 10.5530/jyp.2017.9.113 · Published
Objective: To evaluate the pattern of adverse drug reactions (ADRs) reported in cancer patients receiving anticancer drugs in an adverse drug reaction monitoring centre (AMC). Methods: The anticancer drug related ADRs re…
- Article
An Intensive Monitoring of Adverse Drug Reactions among Elderly Patients Hospitalized in Medical Wards of a Tertiary Care Hospital
Dinesh Zaverbhai Kamejaliya, Jigar Dilipkumar Kapadia, Chetna Kalpan Desai, Mira Kiran Desai
pp. 598–604 · DOI: 10.5530/jyp.2017.9.114 · Published
Objective: To evaluate the pattern of adverse drug reactions in elderly patients hospitalized in medical wards at a tertiary care hospital in India. Methods: Elderly patients≥60 years hospitalized in three randomly selec…
- Article
A Comparative Study of Once Daily versus Twice Daily Tacrolimus in Liver Transplantation
Shamilin Stephen, Ranju Markkassery, Bismi Edathuruthil Sainudheen, Merin Babu, Dinesh Balakrishnan, Sudhindran Surendran, Uma Devi Padma
pp. 605–609 · DOI: 10.5530/jyp.2017.9.115 · Published
Background: Once daily (OD) tacrolimus, recently launched for post liver transplant immunosuppression might offer better compliance and efficacy compared to standard twice daily (BID) tacrolimus. Data from India, however…
- Article
Evaluation of Combination of Low Dose Atorvastatin Plus Ezetimibe and Aspirin in the Treatment of Atherosclerotic Vascular Disease
Godlaveti Vijay Narasimha Kumar, Akkula Jyothi, Chitikela P Pullaiah, Veluri Kishore Sastha Ram, Sandopa Dhanunjaya, Gaddam Dayanand Reddy
pp. 610–615 · DOI: 10.5530/jyp.2017.9.116 · Published
Objective: To evaluate the effect of combination of low dose of atorvastatin plus ezetimibe and aspirin in the treatment of Atherosclerotic Vascular Disease (AVD) with special emphasis on rhabdomyolysis. Experimental Des…
Case Report
- Article
Management of Thyrotoxicosis and its Associated Atrial Fibrillation- A Case Report
Palanisamy Sivanandy, Lee Chun Mey
pp. 616–619 · DOI: 10.5530/jyp.2017.9.117 · Published
Background: Thyrotoxicosis is a condition occurs when excessive thyroid hormone level produced by overactive thyroid gland. It is the risk factor of getting atrial fibrillation (AF) as it could exert marked influences on…