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Journal of Young Pharmacists volume 10, issue 1 cover
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Cover: Journal of Young Pharmacists

Journal of Young Pharmacists

Volume 10, Issue 1

· pp. 1–130 · 28 articles

Volume
10
Issue
1
Published
Pages
1–130
Articles
28
Sections
4
ISSN
Print - 0975-1483 | Online - 0975-1505
Journal
JYP
EditorialOriginal ArticleShort CommunicationCase Report

In this issue

Editorial

  1. Forum Article

    Does Electromagnetic Radiation affect drug stability?

    Subramani Parasuraman, Krishnamoorthy Venkates Kumar

    pp. 1–2 · DOI: 10.5530/jyp.2018.10.1 · Published

    Stability is one of the key determinant in assessing the quality, safety and efficacy of Active Pharmaceutical Ingredient (API) or Finished Pharma ceutical Product (FPP). Stability issues in a pharmaceutical products cou…

Original Article

  1. Article

    Molecular Dynamics Simulation of SIRT1 Inhibitor from Indonesian Herbal Database

    Andika a, Linda Erlina, Azminah a, Arry Yanuar

    pp. 3–6 · DOI: 10.5530/jyp.2018.10.2 · Published

    Objective: Sirtuins are protein deacetylases regulating cellular metabolism, lifespan, stress responses, and linked with diseases pathogenesis such as cancer and neurodegenerative diseases. SIRT1, one of human seven sirt…

  2. Article

    Pharmacophore-Based Virtual Screening from Indonesian Herbal Database to Finding New Inhibitor of HDAC4 and HDAC7

    Linda Erlina, Andika a, Azminah a, Arry Yanuar

    pp. 7–11 · DOI: 10.5530/jyp.2018.10.3 · Published

    Objective: Nowadays, many researchers focused on finding and developing the new inhibitor of HDAC4 and HDAC7 using in silico tools such as docking, pharmacophore approaches, and molecular dynamics simulation. The aim of …

  3. Article

    Synthesis and Pain Inhibition Activity of the Analogs of 1-Allyl-3-Benzoylthiourea for New Analgesic Lead Compound Discovery

    Alvan F. Shalas, Siswandono s, Marcellino Rudyanto

    pp. 12–15 · DOI: 10.5530/jyp.2018.10.4 · Published

    Objective: The study aimed to synthesize four analogs of 1-allyl-3-benzoylthiourea (R= H; 2-Cl; 3-Cl; and 4-Cl), and evaluate their pain inhibition activities. Method: The chemical structure was drawn assisted by Chem- D…

  4. Article

    Green Synthesis of Silver Nanoparticles Using Hydnocarpus pentandra Leaf Extract: In-vitro Cyto-Toxicity Studies Against MCF-7 Cell Line

    Krishna kumar K, Dinesh kumar B, Rini Ramesh Punathil

    pp. 16–19 · DOI: 10.5530/jyp.2018.10.5 · Published

    Objective: To synthesize silver nanoparticles from leaves extract ofHydnocarpus Pentandra (H. Pentandra) and test the anti-cancer activity of synthesized silver nanoparticles against breast cancer cell line (MCF-7 cells)…

  5. Article

    The Isolation of Myristicin from Nutmeg Oil by Sequences Distillation

    Susana Elya Sudradjat, Kris Herawan Timotius, Abdul Mun’im, Effionora Anwar

    pp. 20–23 · DOI: 10.5530/jyp.2018.10.6 · Published

    Background: Nutmeg oil is used in Asia as a traditional medicine for a stomach cramps, diarrhea, and insomnia. It’s quality need to be improved by increasing myristicin content. Objectives: This study aimed to increase t…

  6. Article

    Formulation Optimization and Performance Evaluation of Papain and Clove Oil based Chemo-mechanical Caries Removing Gel

    Captain Khushali, Kale Rupali, Shirolkar Satish

    pp. 24–26 · DOI: 10.5530/jyp.2018.10.7 · Published

    Objective: To formulate and optimise stable caries removing gel using naturally extracted papain and clove, for non– invasive chemo–mechanical removal of dental caries. Methodology: Gel formulation was prepared using nat…

  7. Article

    Formulation and in vitro Penetration Study of Transfersomes Gel Containing Gotu Kola Leaves Extract (Centella asiatica L. Urban)

    Silvia Surini, Sarah, Joshita Djajadisastra

    pp. 27–31 · DOI: silvia.surini@ui.ac.id · Published

    Objective: Asiaticoside from gotu kola leaves extract (Centella asiatica L. Urban) could be used for anti-aging cosmetics. Nevertheless, its skin penetration is difficult, since it has a high molecular weight. Transferso…

  8. Article

    Formulation and Characterization of pH based Stimuli Sensitive based Hydrogels for the Treatment of Ocular Infection

    Nagalakshmi Sethuraman, Anbarasan Balu, Ramesh Selvaraj, Thanka Johnson, Shanmuganathan Seetharaman

    pp. 32–36 · DOI: 10.5530/jyp.2018.10.9 · Published

    Objective: The goal of the study was to formulate and characterized the pH stimuli sensitive based hydrogels for the effective treatment of infected eye. Method: Simple method of preparation was adapted. Result: The opti…

  9. Article

    Formulation and Characterization of Rice Bran Oil in Alginate Microcapsules

    Siti Nashihah, Abdul Mun’im, Sutriyo s, Fadlina Chany Saputri

    pp. 37–40 · DOI: 10.5530/jyp.2018.10.10 · Published

    Objective: This study was conducted to evaluate the encapsulated Rice Bran Oil with sodium alginate to improve stability and reduce rancidity by using ionic gelation method. Method: Response Surface Methodology design we…

  10. Article

    Gel Formulation Containing Microcapsules of Grape Seed Oil (Vitis vinifera L.) for Skin Moisturizer

    Silvia Surini, Khansa Nursatyani, Delly Ramadon

    pp. 41–47 · DOI: 10.5530/jyp.2018.10.11 · Published

    Objective: Grape seed oil (GSE) from Vitis vinifera L. has a high linoleic acid content, which plays a role in the skin moisturizing. However, linoleic acid is a liquid form and easily oxidized. The aims of this research…

  11. Article

    Analysis of Rifampicin in Dried Blood Spot of Tuberculosis Patients for Therapeutic Drug Monitoring using High Performance Liquid Chromatography

    Yahdiana Harahap, Fauzan Alkindy, Ghina Ashiila, Rahmayanti r

    pp. 48–51 · DOI: 10.5530/jyp.2018.10.12 · Published

    Objective: This research aimed to determine rifampicin in dried blood spot of tuberculosis patients using cilostazol as internal standard by high performance liquid chromatography for supporting therapeutic drug monitori…

  12. Article

    Reliable and Sensitive Stability Indicating Assay Method of Armodafinil

    CN Prathyusha Naik, KB Chandra Sekhar

    pp. 52–56 · DOI: 10.5530/jyp.2018.10.13 · Published

    Objective: A reliable RP-HPLC SIAM (stability indicating assay method) was developed for the approximation of armodafinil in presence of its degradation product in pharmaceutical dosage forms. Materials and Methods: Mobi…

  13. Article

    Allantoin Alleviates Male Sexual Dysfunction in Diabetic Rats through Augmenting the Level of Testosterone

    Syed Kashif, Rema Razdan, Rohitash Jamwal, Sumanta Kumar Goswami

    pp. 57–61 · DOI: 10.5530/jyp.2018.10.14 · Published

    Objective: A majority of the diabetic patients experience sexual dysfunction. The objective of the study was to investigate the effect of allantoin on sexual dysfunction in diabetic rats. Methods: Streptozotocin-induced …

  14. Article

    Natural Aldose Reductase Inhibitors Act as Potent Agonists of PPARγ

    Angeline Julius, Waheeta Hopper

    pp. 62–65 · DOI: 10.5530/jyp.2018.10.15 · Published

    Background: Diabetes and cancer have been the leading cause of mortality all over the world. Studies on association between diabetes and cancers over a decade indicate a positive relationship between them. Epidemiologic …

  15. Article

    Social Aspects of Antibiotic use in the South and East Asian Students and General Population

    Jas Min Oh, Long Chiau Ming, Faizah Safina Bakrin, Bey Hing Goh, Learn Han Lee, Tahir Mehmood Khan

    pp. 66–73 · DOI: 10.5530/jyp.2018.10.16 · Published

    Background: This study explored the knowledge of attitudes to and perception of consumption of antibiotics, and understanding of antibiotic resistance among students and general population across South and East Asia regi…

  16. Article

    Gender-based Early Immunological Response to Antiretroviral Therapy in HIV Patients at a Tertiary Care Hospital in Coastal Karnataka

    Kamath Priyanka, Chowta Mukta Nithyananda, Ramapuram John Thomas, Shenoy Ashok Kudgi, Hadigal Sanjay

    pp. 74–77 · DOI: 10.5530/jyp.2018.10.17 · Published

    Background and Objective: To compare the immunological response to antiretroviral therapy between genders and to identify other factors that could affect the immunological response. Methods: This was a prospective, obser…

  17. Article

    Inventory Management using Matrix Analysis and Inventory Index in an Oncology Pharmacy of a Tertiary Care Teaching Hospital

    Subratha C, Naveen Kumar, Bryal D’ Souza, Arun Mavaji, Rajesh Kamath

    pp. 78–81 · DOI: 10.5530/jyp.2018.10.18 · Published

    Aim: To apply matrix analysis using the principles of Always Better Control(ABC), Vital, Essential and Desirable (VED) analysis and inventory index for inventory control and to identify the drugs that require management …

  18. Article

    Antithrombotic Utilization Evaluation in Patients Suffering from Deep Vein Thrombosis at a Tertiary Care Teaching Hospital

    Chandresh B. Dumatar, Sandip S. Jadav, Aashutosh J. Patel

    pp. 82–85 · DOI: 10.5530/jyp.2018.10.19 · Published

    Objective: To evaluate the usage pattern of antithrombotic in patients suffering from deep vein thrombosis (DVT) in a tertiary care teaching hospital. Methods: It was an observational, prospective and single centre study…

  19. Article

    Effectiveness of Pharmacist Intervention (SAHELI) on Family Planning, Maternal Care and Child Care Among Rural Women

    Dilip Chandrasekhar, Aswathi Shaji, Ardra Mariet Jose, Asifa Abdul Kareem, Levin Thomas

    pp. 86–90 · DOI: 10.5530/jyp.2018.10.20 · Published

    Background: Due to low literacy rates and poor economic status rural women are either completely or partially unaware about modern Family Planning techniques and proper scientific maternal care and child care. “SAHELI”- …

  20. Article

    Prevalence and Determinants of Over-the-Counter Analgesics Usage among Patients attending Primary Health Care Centers in Jeddah, Saudi Arabia

    Shaza Dawood Babakor, Majid Mohammed Al Ghamdi

    pp. 91–97 · DOI: 10.5530/jyp.2018.10.21 · Published

    Objective: To estimate the prevalence and describe the pattern of OTC use among patients attending primary healthcare (PHC) centers, and to assess their knowledge and attitude regarding the related side effects. Method: …

  21. Article

    Prescribing Patterns of Antidepressants among Depressive Men in Malaysia: A Survey

    Abdul Rahman Fata Nahas, Syed Azhar Syed Sulaiman

    pp. 98–101 · DOI: 10.5530/jyp.2018.10.22 · Published

    Objective: In recent studies on the prescribing pattern of antidepressants, selective serotonin reuptake inhibitors (SSRIs) were the most prescribed antidepressants in many countries. Yet, little reports investigated dep…

  22. Article

    Cost Analysis of Re-Sterilization Procedure of Re-Usable Devices in a Hospital

    Naveen Kumar, Vrunda Lothlikar, Bryal D’ Souza, Usha Rani, Swapna BV

    pp. 109–112 · DOI: 10.5530/jyp.2018.10.24 · Published

    Aim: To analyse the costs and recommend rectification in functioning of CSSD for qualitative delivery of patient care. Objectives: Assess the effectiveness of sterilization procedures and calculate the cost of re-sterili…

  23. Article

    A Retrospective Evaluation of Cutaneous Adverse Drug Reactions (CADRs) Due to Antibiotics Using Naranjo Adverse Drug Reactions (ADRs) Probability Scale

    Mohammed Helmy Faris Shalayel, Ietimad Abdelsalam Mohamed Ayed, Mohammed Ayed Huneif, Yousif Mohammed Kordofani

    pp. 113–116 · DOI: 10.5530/jyp.2018.10.25 · Published

    Cutaneous adverse drug reactions (CADRs) have been found to be one of the most common adverse drug reactions (ADRs) in many studies. There is no common globally accepted tool for causality grading of ADRs to be utilized …

  24. Article

    A Prospective Study to Evaluate Prescription Pattern of Second Line Antiretroviral Therapy Given to HIV Patients

    Jigar P. Modi, Amita Kubavat, Shailesh Mundhava, Usha Lalwani

    pp. 117–122 · DOI: 0.5530/jyp.2018.10.26 · Published

    Aims: To evaluate prescription pattern during second line Antiretroviral Therapy (ART) at tertiary care hospital. Despite a very large number of patient being covered under ART, there are limited data in Indian populatio…

Short Communication

  1. Communication

    Upsurge in BCG Vaccine Induced lymphadenitis: Case Series

    Manju V, Amrita Parida, Asha Hegde, Phalguna Kousikakatakam

    pp. 123–125 · DOI: 10.5530/jyp.2018.10.27 · Published

    Introduction: Tuberculosis is one of the serious healthcare concerns of the world today. The only vaccine available for tuberculosis till date is the BCG vaccine. It is one of the safest vaccine and is less commonly asso…

Case Report

  1. Article

    Case Report on Less Potent Corticosteroid Induced Altered Mental Status and Its Management At Secondary Care Public Hospital

    Chandrasekar Keerthana, Balasubramanian Madhubala, Nanjan Loghraj, Sivasankaran Ponnusankar

    pp. 126–128 · DOI: 10.5530/jyp.2018.10.28 · Published

    Objective: Patients receiving high doses of corticosteroids reported developing psychiatric disorders and rarely, Altered Mental Status (AMS) and disorientation is observed. Hence, corticosteroids administration should b…

  2. Article

    Sorafenib Induced Hand and Foot Syndrome

    Dhanya Susan, Malini M, Remya Reghu

    pp. 129–130 · DOI: 10.5530/jyp.2018.10.29 · Published

    Sorafenib a multikinase inhibitor has been approved by the FDA for the treatment of thyroid, hepatocellular and renal cell carcinoma. Hand-foot syndrome / palmar – plantar erythrodysesthesia causes redness, swelling and …