Article

Whole Foods Versus Isolated Compounds: Why Nutrition Trials Keep Asking the Wrong Question

Mueen Ahmed KK*1

  1. 1Manuscript Technomedia LLP, No. 22 (New No. 40), 3rd Cross, Vivekananda Nagar, Bengaluru, Karnataka, INDIA.

Volume 2, Issue 1 · pp. 73–73 · PUBLISHED 2026 · DOI: 10.5530/lsrc.2.1.9

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ABSTRACT

Large randomized trials of isolated antioxidant compounds have repeatedly returned null or adverse results, even as whole-food dietary patterns rich in the same compounds remain associated with better health. I write to suggest that this is not a paradox but a predictable consequence of a recurring design choice: testing single high-dose nutrients in isolation.

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    KK*, M. A. (2026). Whole Foods Versus Isolated Compounds: Why Nutrition Trials Keep Asking the Wrong Question. Life Science Research Communications, 2(1), 73–73. https://doi.org/10.5530/lsrc.2.1.9