Optimization of Ultrasound-assisted extraction of polyphenols, tannins and epigallocatechin gallate from barks of Stryphnodendron adstringens (Mart.) Coville bark extracts

ABSTRACT

Background: Stryphnodendron adstringens (Mar.) Coville is a native plant from Brazil, rich in phenolic compounds and used on popular medicine as a wound healing agent, in the treatment of gastric lesions and as antimicrobial. Materials and Methods: Ultrassound-assisted extraction (UAE) was applied to extraction of epigallocatechin gallate (EGCG), total polyphenols (TP) and total tannins (TT) content from barks of Stryphnodendron adstringens (Mar.) Coville. Several operating parameters, namely extraction time (min), liquid to solid ratio (mg/mL), ethanolic strength (%, v/v), were optimized using response surface methodology (RSM) with a Box-Behnken design. Results: By using the desirability function approach, the optimum UAE conditions to obtain desirable extraction yields for all these metabolites simultaneously were found at the extraction time of 30 min, solid to liquid ratio of 4 mg/mL and ethanolic strength of 65. Under these conditions, the epigallocatechin gallate, total polyphenols and total tannins content were 0.31; 22.95 and 11.95 % (w/w), respectively. Conclusion: The results indicated that knowledge gained from this study should be helpful to further exploit and apply this resource and also showed the feasibility of ultrasound-assisted extraction for obtaining GEGC, TP and TT from barks of S. adstrigens.

KEYWORDS

• Desirability function
• optimization
• response surface methodology
• Stryphnodendron adstringens
• ultrassound-assisted extraction

Showing references and in-text citations exactly as published.

• DOI10.4103/0973-1296.133287Copy

RELATED ARTICLES

Matched on section and article type within this issue of PM.

• Article · VOLUME 10, ISSUE 38SAqueous extract from taxus baccata inhibits adenosine deaminase activity significantly in cancerous and noncancerous human gastric and colon tissuesZahide Esra Durak, Süleyman Büber, Erdinç Devrim, Hilmi Kocaoğlu2, İlker Durak · pp. 214–216Original ArticleSame type: Article
• Article · VOLUME 10, ISSUE 38SChitosan and blueberry treatment induces arginase activity and inhibits nitric oxide production during acetaminophen‑induced hepatotoxicityEda Ozcelik, Sema Uslu, Dilek Burukoglu, Ahmet Musmul · pp. 217–224Original ArticleSame type: Article
• Article · VOLUME 10, ISSUE 38SEfficiency and selectivity of triterpene acid extraction from decoctions and tinctures prepared from apple peelsAntonio C. Siani, Marcos J. Nakamura, Daniel S. dos Santos, José L. Mazzei, Adriana C. do Nascimento, Ligia M. M. Valente · pp. 225–231Original ArticleSame type: Article
• Article · VOLUME 10, ISSUE 38SAntiproliferative activity of Vallaris glabra Kuntze (Apocynaceae)Siu Kuin Wong, Yau Yan Lim, Sui Kiong Ling, Eric Wei Chiang Chan · pp. 232–239Original ArticleSame type: Article