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Physicochemical Standardization of Mucilage Obtained from Althaea officinalis Linn – Root

Mazhar Husain1, Abdul Wadud1★, Hamiduddin Hamiduddin2, Gulamuddin Sofi1, Shaista Perveen1, Khadeeja Abdul Hafeez1★ Corresponding author

  1. 1Departments of Ilmul Advia (Pharmacology), Institute of Unani Medicine, Bengaluru, Karnataka, India.
  2. 2Ilmul Saidla (Unani Pharmacy), National Institute of Unani Medicine, Bengaluru, Karnataka, India.

CORRESPONDENCE

Abdul Wadud

Departments of Ilmul Advia (Pharmacology), Institute of Unani Medicine, Bengaluru, Karnataka, India.

drwadud87@gmail.com

Received: 03-10-2018; Revised: 13-11-2018; Accepted: 12-11-2018.

Volume 15, Issue 62S · pp. S155–S161 · PUBLISHED 26 April 2019 · DOI: 10.4103/pm.pm_506_18

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ABSTRACT

Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant, but other species are less explored. Objective: To evaluate the antioxidant and anti-inflammatory activities of <em>Cissus arnottiana</em>. Materials and Methods: The methanolic extract of <em>C. arnottiana</em> leaves was evaluated for antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide, and hydroxyl radical scavenging assays. Anti-inflammatory activity was assessed using the carrageenan-induced rat paw edema model. Results: The extract showed significant antioxidant activity in a dose-dependent manner. In the anti-inflammatory assay, the extract at 200 and 400 mg/kg doses significantly reduced paw edema compared to the control group. Conclusion: <em>C. arnottiana</em> possesses significant antioxidant and anti-inflammatory properties, supporting its traditional use.

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    Husain, M., Wadud, A., Hamiduddin, H., Sofi, G., Perveen, S., & Hafeez, K. A. (2019). Physicochemical Standardization of Mucilage Obtained from Althaea officinalis Linn – Root. Pharmacognosy Magazine, 15(62S), S155–S161. https://doi.org/10.4103/pm.pm_506_18