Evaluation of Antioxidant and Anti-inflammatory Activities of Selected Cissus Species
Preeti Rawat1★, Pinki Rawat2, Piyush Kumar3, Sabita Kumari4, Anil Kumar1, Mahesh Pal1★ Corresponding author
- 1Phytochemistry Division, CSIR‑National Botanical Research Institute, Lucknow.
- 2Department of Pharmacy, Maharana Pratap College of Pharmacy, Kanpur.
- 3Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh.
- 4Department of Pharmaceutical Sciences and Technology, BIT, Ranchi, Jharkhand, Institute, Lucknow, India.
CORRESPONDENCE
Preeti Rawat
Phytochemistry Division, CSIR‑National Botanical Research Institute, Lucknow.
Received: 31-07-2020; Revised: 25-08-2020; Accepted: 22-12-2020.
Volume 17, Issue 73 · pp. 120–126 · PUBLISHED 15 April 2021 · DOI: 10.4103/pm.pm_333_20
ABSTRACT
Objectives: The present work was aimed at investigating the phytochemicals of methanolic extract of L. procumbens leaves and its isolated mixtures from column fractions. Materials and Methods: The method was successfully developed and two new compounds (chlorogenic acid and 7‑hydroxyflavanone) by liquid chromatography (LC)‑electrospray ionization (ESI)‑MS/MS and four new compounds (lactucin, isorhametin, 1‑monopalmitin, and 1‑hexacosanol) by ultra‑performance liquid chromatography (UPLC)‑ESI‑quad time of flight (QTOF)/MS in L. procumbens were identified. Identification of compounds by LC‑ESI‑MS/ MS and UPLC‑ESI‑QTOF/MS was identified based on the accurate mass of pseudomolecular [M+H]+ ion tandem mass spectrometry (MS/MS) data and by comparing retention times, mass spectra, and molecular weights with those published in the literature. Results: The six new compounds, namely chlorogenic acid, 7‑hydroxyflavanone, lactucin, isorhametin, 1‑monopalmitin, and 1‑hexacosanol were identified by in L. procumbens. Conclusion: A total of 26 compounds by gas chromatography‑MS and five compounds by LC mass‑ESI tandem mass spectrometry (LC‑ESI‑MS/ MS) and seven compounds by UPLC‑ESI tandem mass spectrometry/ quadrupole‑time‑of‑flight‑mass spectrometry (UPLC‑ESI‑QTOF/MS) technique were identified.
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Rawat, P., Rawat, P., Kumar, P., Kumari, S., Kumar, A., & Pal, M. (2021). Evaluation of Antioxidant and Anti-inflammatory Activities of Selected Cissus Species. Pharmacognosy Magazine, 17(73), 120–126. https://doi.org/10.4103/pm.pm_333_20