Article

Isolation, Purification and Characterization of L-Carvone from Mentha longifolia Using Fractional Distillation and Quantified by Gas Chromatography

Hayat M. Mukhtar1, Nishant Kumar2, Amandeep Singh2, Abhay Sharma2, Priyanka P2, Prince Ahad Mir2★★ Corresponding author

  1. 1SBS College of Pharmacy, Sohian Kalan, FC Road Amritsar, Punjab, INDIA.
  2. 2Khalsa College of Pharmacy, GT Road Amritsar, Punjab, INDIA.

CORRESPONDENCE

Prince Ahad Mir

Khalsa College of Pharmacy, GT Road Amritsar, Punjab, INDIA.

princeahad@kashmiruniversity.net

Received: 14-05-2023; Revised: 06-07-2023; Accepted: 01-09-2023.

Volume 16, Issue 1 · pp. 156–160 · PUBLISHED · DOI: 10.5530/pres.16.1.20

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ABSTRACT

Menta longifolia is an aromatic herb consists of dried aerial parts of Mentha longifoliabelongs to family Lamiaceae. Overground parts of the plant yield 2-4% of an essential oil, of which the chief component appears to be the monoterpene ketone, carvone. Mentha longifolia thus approaches spearmint (Mentha spicata) rather than peppermint (M. piperita) in oil composition. Other major constituents of the essential oil, according to various studies, include piperitenone and its oxide, piperitone and its oxide and pulegone. The present study involves isolation of l-Carvone from Mentha longifolia using fractional distillation as a tool for separation which was quantified using Gas chromatography. Characterization of purified L-Carvonewas done using NMR spectroscopy (1HNMR and 13C-NMR). Fractions collected using fractional distillation was evaluated for anti-microbial activity for further studies.

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    Mukhtar, H. M., Kumar, N., Singh, A., Sharma, A., P, P., & Mir, P. A. (). Isolation, Purification and Characterization of L-Carvone from Mentha longifolia Using Fractional Distillation and Quantified by Gas Chromatography. Pharmacognosy Research, 16(1), 156–160. https://doi.org/10.5530/pres.16.1.20