Review

Phytochemical and Pharmacological Properties of Tinospora cordifolia (Giloy)

Richa Kothari1★, Manoj Kumar Bajhaiya2, Shefali Soni3, Abhishek Kumar4, Samreen Ali5, Ankit Rajput2, Prashant kumar2, Sagar Shrotriya6, Kanchan Thakur6★ Corresponding author

  1. 1Department of Chemistry, School of Science, ITM University, Gwalior, Madhya Pradesh, INDIA.
  2. 2Department of Pharmacology, School of Pharmacy, ITM University, Gwalior, Madhya Pradesh, INDIA.
  3. 3Department of Pharmaceutics, Sanjeev Agrawal Global Educational, University Bhopal, Madhya Pradesh, INDIA.
  4. 4Department of Pharmaceutics, Intellicom College of Pharmaceutical Sciences, Bhopal, Madhya Pradesh, INDIA.
  5. 5Department of Pharmaceutics, Mittal Institute of Pharmacy, Bhopal, Madhya Pradesh, INDIA.
  6. 6School of Pharmacy and Research Center, Sanskriti University, Chhata, Mathura, INDIA.

CORRESPONDENCE

Richa Kothari

Department of Chemistry, School of Science, ITM University, Gwalior-474001, Madhya Pradesh, INDIA.

Richakothari@itmuniversity.ac.in

Received: 14-05-2025; Revised: 24-07-2025; Accepted: 08-09-2025.

Volume 17, Issue 4 · pp. 1171–1182 · PUBLISHED Oct-Dec 2025 · DOI: 10.5530/pres.20252350

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ABSTRACT

Tinospora cordifolia (commonly known as Giloy or Guduchi) is a revered herb in traditional Ayurvedic medicine, widely recognized for its rejuvenating properties. The plant’s therapeutic effects stem from a rich profile of phytochemicals-alkaloids, terpenoids, lactones, and polysaccharides-responsible for diverse pharmacological activities such as immunomodulation, antioxidant, anti-inflammatory, antidiabetic, antimicrobial, and hepatoprotective effects. This paper explores the phytochemical constituents, pharmacological potentials, and clinical relevance of T. cordifolia, with a focus on its mechanisms of action and its growing role in integrative medicine, particularly post-COVID-19. The review also highlights the necessity of more rigorous scientific studies and standardization to bridge traditional uses and modern therapeutic applications.

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    Kothari, R., Bajhaiya, M. K., Soni, S., Kumar, A., Ali, S., Rajput, A., kumar, P., Shrotriya, S., & Thakur, K. (2025). Phytochemical and Pharmacological Properties of Tinospora cordifolia (Giloy). Pharmacognosy Research, 17(4), 1171–1182. https://doi.org/10.5530/pres.20252350