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Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

Essam Abdel-Sattar1, Dina Abou-Hussein1,2★, Frank Petereit3★ Corresponding author

  1. 1Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt
  2. 2Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
  3. 3University of Münster, Institute of Pharmaceutical Biology and Phytochemistry, Hittorfstraße 56, D-48149 Münster, Germany

CORRESPONDENCE

Dina Abou-Hussein

*Address for correspondence: Dr. Dina Abou-Hussein, Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.

dinaabouhussein@hotmail.com

Revised: 09-06-2014.

Volume 7, Issue 1 · pp. 14–17 · PUBLISHED January-March 2015 · DOI: 10.4103/0974-8490.147136

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ABSTRACT

Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), D-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.

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    Abdel-Sattar, E., Abou-Hussein, D., & Petereit, F. (2015). Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia. Pharmacognosy Research, 7(1), 14–17. https://doi.org/10.4103/0974-8490.147136