Studies on in vitro Anti-Diabetic Activities of the Epigeic Earthworm, Eisenia fetida Extract
Aishwarya Shetty1, Pulikeshi M. Biradar1★★ Corresponding author
- 1Department of Zoology, Karnatak University, Dharwad, Karnataka, INDIA.
CORRESPONDENCE
Pulikeshi M. Biradar
Department of Zoology, Karnatak University, Dharwad, Karnataka, INDIA.
Received: 11-05-2024; Revised: 14-07-2024; Accepted: 18-08-2024.
Volume 13, Issue 2 · pp. 316–321 · PUBLISHED · DOI: 10.5530/ajbls.2024.13.40
ABSTRACT
Aim:Diabetes is considered as one of the serious complications and disorder in recent years. So, the present work was undertaken to investigate the anti-diabetic activity using Eisenia fetidaearthworm extract. Materialsa and Methods:The anti-diabetic activity was carried out by using different concentrations of earthworm, Eisenia fetidaextract with two different methods, alpha-amylase inhibitory assay and glucose uptake assay by using standard drug Metformin and Metronidazole respectively. Results:Results revealed that the earthworm, Eisenia fetidaextract exhibit anti-diabetic activity by inhibiting alpha-amylase activity and also by increasing the glucose uptake in the cells. Thus, earthworm Eisenia fetidaextract may serve as an alternative anti-diabetic drug to prevent diabetic complications in near future. Alpha-amylase assay Anti-diabetic activity Eisenia fetida and Glucose uptake assay
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Shetty, A., & Biradar, P. M. (). Studies on in vitro Anti-Diabetic Activities of the Epigeic Earthworm, Eisenia fetida Extract. Asian Journal of Biological and Life sciences, 13(2), 316–321. https://doi.org/10.5530/ajbls.2024.13.40