Antidiabetic and Antimicrobial Properties of Leaf and Bark Extracts of Cerbera odollam

ABSTRACT

Aim:The study aimed to identify the phytochemical components, antibacterial, antifungal, and antidiabetic activity in methanol and aqueous extract of Cerbera odollamleaves and bark using different testing techniques. Materials and Methods:This research work evaluated the antibacterial and anti-diabetic effects of methanol and aqueous extracts of Cerbera odollam, extracts were generated by drying and extracting the leaf and bark using a soxhlet apparatus. The antibacterial and antifungal activity was determined using the well diffusion method. Results:The antidiabetic role of the plant extracts was analyzed using alpha-amylase inhibition screening assay followed by starch iodine assay. The results were validated with UV-VIS Spectroscopy and FTIR analysis. The methanolic extract of the leaf possesses maximum antibacterial, antifungal, and antidiabetic activity. Conclusion:This study provides new insights and scope to analyze the methanol and aqueous bark extracts of Cerbera odollamfor their effective antidiabetic activity. Antidiabetic Antimicrobial Cerbera odollam FTIR Phytochemicals

KEYWORDS

• Antidiabetic
• Antimicrobial
• Cerbera odollam
• FTIR
• Phytochemicals

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• DOI10.5530/ajbls.2024.13.41Copy

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