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Asian Journal of Biological and Life sciencesNOW IN
Article

Antioxidant and Antimicrobial Potentiality Assessment of Bioactive Leaf Extracts of Four Traditionally Used Medicinal Plants

Himashri Deka1, Chayanika Devi2, Mohammad Tabish3, Dimbeswar Das4, Chunamoni Das5, Pankaj Kalita6★★ Corresponding author

  1. 1Department of Life Sciences and Bioinformatics, Assam University, Diphu Campus, Karbi Anglong, Assam, INDIA.
  2. 2Department of Zoology, Pub Kamrup College, Baihata Chariali, Kamrup, Assam, INDIA.
  3. 3Department of Pharmacology, College of Medicine, Shaqra University, Shaqra, SAUDI ARABIA.
  4. 4Department of Botany, Eastern Karbi Anglong College, Karbi Anglong, Assam, INDIA.
  5. 5Department of Botany, S. B. M. S. College, Sualkuchi, Assam, INDIA.
  6. 6Department of Zoology, Eastern Karbi Anglong College, Karbi Anglong, Assam, INDIA.

CORRESPONDENCE

Pankaj Kalita

Department of Zoology, Eastern Karbi Anglong College, Karbi Anglong, Assam, INDIA.

kalita.pankaj9@gmail.com

Received: 06-06-2024; Revised: 19-07-2024; Accepted: 22-08-2024.

Volume 13, Issue 2 · pp. 481–490 · PUBLISHED · DOI: 10.5530/ajbls.2024.13.60

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ABSTRACT

Aim:The present study involves the screening and assessment of phytochemical composition of V. negundo, A. carambola, A. indicaand J. gendarussaleaves extract. The extracts were further assessed for their antioxidant and antimicrobial potentialities against Staphylococcus aureus, E. coli, Enterococcuswhich have clinical importance in the disease biology. Material and Methods:Leaves of four plants, namely, Vitex negundo, Averrhoea carambola, Azadirachta indica and Justicia gendarussa, were extracted with hexane, chloroform, ethanol and methanol to determine phytochemical potential and their antioxidant and antimicrobial activity. Phytochemical potentiality was tested by spectrophotometric methods and the antimicrobial activities against Staphylococcus aureus, Escherichia coli, Enterococcuswere screened using disc diffusion methods. Antimicrobial activity was calculated by measuring the diameter of the Inhibition Zone (IZ) around the discs. Results:The qualitative analysis in the study identified polyphenols, flavonoids, carbohydrates and tannins in the extracts and the amount of flavonoids, phenols, tannins and carbohydrates were quantitatively determined. All extracts contained alkaloids, flavonoids, cardiac glycosides and tannins, indicating that they had rich phytochemical profiles. Significantly, the chloroform extract of Vitex negundocontained the most carbohydrates, whereas the chloroform extract of Justicia gendarussadisplayed the highest level of flavonoids. Whereas, the methanol extract of Vitex negundodisplayed considerable phenolic components and the hexane extract of Justicia gendarussashowed the best antioxidant activity. The methanol and chloroform extracts of V. negundopossess antimicrobial properties in this study. Conclusion:The results of the present investigation suggest that studied plants are excellent sources of nutraceuticals against various ailments. The methanol extract of Vitex negundodisplayed considerable phenolic components and the hexane extract of Justicia gendarussacontained the highest antioxidant activity. As methanol extract of V. negundohas significant antimicrobial property, therefore, the selected extract may be explored by phytomolecular analysis as an antimicrobial agent. Antimicrobial Antioxidant Medicinal supplements Phytochemical

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    Deka, H., Devi, C., Tabish, M., Das, D., Das, C., & Kalita, P. (). Antioxidant and Antimicrobial Potentiality Assessment of Bioactive Leaf Extracts of Four Traditionally Used Medicinal Plants. Asian Journal of Biological and Life sciences, 13(2), 481–490. https://doi.org/10.5530/ajbls.2024.13.60