Volume 13, Issue 1

An Insight into the Host-Pathogen Interactions between Macrophage and Different Microbial Species: A Detailed Approach

Aparajita Chakraborty, Malavika Bhattacharya

pp. 1–8 · DOI: 10.5530/ajbls.2024.13.1 · Published

The macrophage phagolysosome possesses a highly acidic environment which explains its antimicrobial properties. Many strains of bacterial strains which are Gram-positive such as Staphylococcus aureus replicates within th…

Navigating Biologics Regulation: A Deep Dive into Australian Compliance

Nayana Saji, Deeksha Kethareshwara Sujatha, Balamuralidhara Veeranna

pp. 9–21 · DOI: 10.5530/ajbls.2024.13.2 · Published

Biologics are at the forefront of therapeutic breakthroughs, marking a paradigm change in medical therapies in an ever-evolving field. Complex biological products known as biologics are used to treat a variety of illness…

A Systematic Review of the Role Played by Aquaporins in the Etiology of Rheumatoid Arthritis

Debabrata Modak, Shreya Kar, Purnima Singh, Sudipta Kumar Roy, Soumen Bhattacharjee

pp. 27–34 · DOI: 10.5530/ajbls.2024.13.4 · Published

Background: Aquaporins (AQPs) are integral membrane proteins that are essential for preserving the equilibrium of water. These proteins also regulate cell volume and cell migration as well as apoptosis that relates to va…

Verdant Treasures: Unveiling the Ecological Distribution, Conservation Status, and Medicinal Marvels of Pogonatum species in India-A Holistic Review

Sarath Ramesan Velu Vayalil, Swathi Sasidharan Nair, Manoj Gopal Sarayu

pp. 22–26 · DOI: 10.5530/ajbls.2024.13.3 · Published

Pogonatum moss is a fascinating plant that has garnered a lot of attention because of its wide range of biological distribution, potential medical benefits, and conservation implications. This thorough analysis explores …

Phytochemical Screening and in vitro Antibacterial Activity of Hibiscus rosa-sinensis L. Leaf Extracts

Mregangka Dowara, Indrani Gogoi, Shyamalima Saikia

pp. 35–39 · DOI: 10.5530/ajbls.2024.13.5 · Published

Aim: People have used plants as medicine from the beginning of time to treat a variety of diseases. Different bioactive chemicals found in plants make them viable substitutes for traditional antibacterial treatments. Mat…

Estimation of Nutrient Content of Unfermented and Fermented Rice Drinks

Emi Grace Mary Gowshika Rajendran, V. Gowri Ramesh

pp. 40–47 · DOI: 10.5530/ajbls.2024.13.6 · Published

Background: Fermentation of cooked rice has shown to enhance its nutrient content, palatability, organoleptic characteristics and bioavailability of nutrients. Although fermented rice is known to provide immense health b…

Novel Drug Development for Anti-Cholesterol Activity by in silico Analysis: Identification Cholesterol Inhibiting Compounds

Ananya M Kura, R KarukuvelRaja, Thulasi G Pillai

pp. 48–60 · DOI: 10.5530/ajbls.2024.13.7 · Published

Aim: Cholesterol is required for cellular metabolism and steroid hormone production. However, the excessive level leads to the condition known as hypercholesterolemia, which causes cardiovascular illnesses. A number of d…

Methanolic Leaf Extracts of Certain Plants as Larvicides against Teak skeletonizer, Eutectona machaeralis

Madhavi Maddala, Mahesh Lingakari, Srikanth Bandi

pp. 61–66 · DOI: 10.5530/ajbls.2024.13.8 · Published

Aim: The coveted Indian hardwood teak (Tectona grandis) grows well in particular tropical temperatures and soil types. With 8.9 million hectares, India's teak forests are essential to the luxury market. Indian teak trees…

Biotic Stress Response of Local Host on Cassava Mosaic Virus and its Control with selected Essential Oils: An Experimental Approach

Harikumar Kiran, Radhakrishnan Rajalakshmi

pp. 71–78 · DOI: 10.5530/ajbls.2024.13.10 · Published

Aim: The present investigation was done to study the antiviral property of essential oils collected from Cymbopogon flexuosus, Ocimum tenuiflorum and Piper nigrum, on local lesion host Gomphrena globosa, which was mechan…

Evaluation of in vitro Antidiabetic Activity in the Methanolic Extracts of Protoreaster Linckii

A. Maria Selva Francis, Jemma Hermelin Jesy Diaz

pp. 79–82 · DOI: 10.5530/ajbls.2024.13.11 · Published

Background: Diabetes is a chronic illness characterized by a metabolic imbalance that is connected to increased and decreased blood sugar levels. Several natural compounds and pharmaceutical drugs have been studied for t…

Chemical Profiling and in vitro Cytotoxic Properties of Themeda triandra Forssk. Against Human Bone Osteosarcoma Cell Line (MG-63)

Chikkamagaluru Ningegowda Shruthi, Dupadahalli Kotresha

pp. 83–89 · DOI: 10.5530/ajbls.2024.13.12 · Published

Aim: Grasses are an important group of monocotyledonous plants that are utilized as healthy foods as well as remedies against diseases for both humans and livestock. Themeda triandra Forssk. is a grass, which belongs to …

Study on the Therapeutic Potential of Pimenta dioica Phytocompounds Isolated from Stem Extract and its Analysis through GCMS Profiling

Irfana Mol Khalid, Jayasheela Dharmackan

pp. 90–99 · DOI: 10.5530/ajbls.2024.13.13 · Published

Aim: This study aimed to determine the phytochemical constituents present in the various extracts of Pimenta dioica stem through the standard qualitative biochemical and GCMS analysis. Materials and Methods: The phytoche…

A Comparative Study on the in vitro Cytotoxicity and Anti-Cancer Properties of Gold Nanoparticles Derived from Elettaria cardamomum

Sowmya Kizheka Meladom, Ramasamy Thanghavelu Narendhirakannan

pp. 100–108 · DOI: 10.5530/ajbls.2024.13.14 · Published

Aim: This study scrutinizes the anti-cancer potential of gold nanoparticles derived from Elettaria cardamomum pods and seeds. Materials and Methods:The biosynthesized nanoparticles underwent thorough characterization via…

Formulation of Wound Healing Hydrogel Using Carbon Nanoparticles Synthesized from Piper longum

S. Janaranjani, K. Madhanasundareswari, Karukuvelraja Raja

pp. 109–119 · DOI: 10.5530/ajbls.2024.13.15 · Published

Aim: Bacterial infection is a significant factor in the complex process of delayed wound healing. The advent of antibiotic resistance in bacterial isolates led the creation of antimicrobial drugs from new resources. Form…

Myristica Fragrans: A Potent Antibacterial Agent against Food Borne Pathogens

Jinsu Sara Jose, Haripriya Raj, Tessy Anu Thomas

pp. 133–137 · DOI: 10.5530/ajbls.2024.13.17 · Published

The global challenge of drug resistance in pathogenic bacteria has intensified due to the excessive use of antibiotics. In context to this, the antimicrobial activity of flower extract of Myristica fragrans was evaluated…

Evaluation of the in vitro Antioxidant and Cytotoxic Effects of E. hirta Ethanolic Extract

Senniappan Palanisamy, Kolli Srinivas, Mandava Venkata Basaveswara Rao

pp. 138–143 · DOI: 10.5530/ajbls.2024.13.18 · Published

Background: Numerous studies have been carried out to investigate the efficiency of herbal remedies for hepatic illnesses, particularly hepatitis. Aim: This study aimed to evaluate the antioxidant activity (DPPH assay) a…

Effect of Fermentation (Saccharomyces Cerevisiae) on Improvement of Jackfruit Based Nutri Flour

Soumya P. S, Suma Divakar

pp. 144–149 · DOI: 10.5530/ajbls.2024.13.19 · Published

Background:The main deleterious effect of jackfruit consumption is its low digestibility and flatulence factors, caused by the presence of oligosaccharides. Oligosaccharide is a carbohydrate comprised of few saccharides,…

Green Synthesis of Fucoidan-Chitosan Coated Silver Nanoparticles Biocojugates and their Antimicrobial Activity

S. Divyapriya, K. Rajathi

pp. 150–159 · DOI: 10.5530/ajbls.2024.13.20 · Published

Reliable and environmentally friendly methods for the separation of nanoparticles are urgently needed in the field of nanotechnology. Traditional NP synthesis approaches are costly, harmful and detrimental to the atmosph…

Efficacy of Cupping Therapy and Oral Medications in the Management of Non Specific Low Back Pain-A Pilot Study

Ramesh. S. Killedar, Pradeep. S. Shindhe, Vijay Kage, Kartik K. V, Harishankar P. V

pp. 160–167 · DOI: 0.5530/ajbls.2024.13.21 · Published

Background: Globally, non-specific low back pain has grown to be a significant public health concern. Clinical practice guidelines on the management of NSLBP insist on the use of reassurance, physical activity, paracetam…

Molecular Characterization of a New Bacterial Source of Naringinase as Paenibacillus stellifer RAMCM-44 and Fermentative Production of Naringinase at Shake-Flask Level

Rachna Nara, Anushka Tripathi, Nirmala Sehrawat, Anu Sehrawat, Sushil Kumar Upadhyay, Kashish Malik, Mukesh Yadav

pp. 168–175 · DOI: 10.5530/ajbls.2024.13.22 · Published

Aim/Background:Naringin is an important flavonoid present naturally in the citrus fruits. It contributes bitterness to the citrus fruit juices. Biologically, the naringin mediated bitterness can be reduced by naringinase…

Rapid Physicochemical Assessment of Kalawaig Creek in Bukidnon, Philippines

Lalace Albasin Damasco, Vanessa Jean Delgado Arocha, Ella Bucag Quilang, Denzel Matthew Cutor Damole, Leandro Benedict Eduria Miones, Ian Jay Paspe Saldo

pp. 176–186 · DOI: 10.5530/ajbls.2024.13.23 · Published

Aim/Background: Creeks found in the Philippines are essential to the ecosystem. Like Kalawaig Creek in Bukidnon, Philippines, it represents a unique ecosystem with its distinct set of physicochemical conditions supportin…

Exploring Edible Insects: An Investigation in Kamrup District (Assam) and Ri-Bhoi District (Meghalaya), North-Eastern India

Arup Nama Das, Golphina Ahmed, Adani Leshiini, Aditya Das

pp. 187–196 · DOI: 10.5530/ajbls.2024.13.24 · Published

In the ecological context, insects play a crucial role by establishing a connection between people’s livelihoods and the assessment of sustainable practices. The exploration of edible insects as a food source necessitate…

Phytochemical Screening and Antioxidant Activity Evaluation of Selected Philippine Fruit Peels and Pulps

Mildred Dagcuta Pates, Angelo Mark Po Walag, Romeo M. Del Rosario

pp. 197–203 · DOI: 10.5530/ajbls.2024.13.25 · Published

Aim:This research aimed to explore the potential of underutilized plant waste products from Philippine fruits as sustainable sources of phytochemicals, assessing the viability of green extraction methods. It focused on t…

Mapping the Landscape of Drug Delivery Research with a Focus on Artificial Intelligence

Neelaveni Thangavel, Amirah Ibrahim Assiri, Bushra Ibrahim Dighriri, Etlal Mohammad Alnami, Nouf Mohsen Adawi, Nariman Ahmad Alhazemi, Najat Mohammed Bawkar

pp. 204–214 · DOI: 10.5530/ajbls.2024.13.26 · Published

Aim:This study analyzed the landscape of drug delivery research with a bibliometric approach, focusing on Artificial Intelligence (AI) using data from the Web of Science. Materials and Methods: The analysis included 20 y…

Phytochemical Profiling of Bryum argenteum Hedw. and Dumortiera hirsuta (Sw.) Nees.

Swathi Sasidharan Nair, Sarath Ramesan Velu Vayalil, Manoj Gopal Sarayu

pp. 215–220 · DOI: 10.5530/ajbls.2024.13.27 · Published

Aim: Bryophytes are the second largest group of land plants. This study involved phytochemical profiling on a liverwort representative from a primitive group and one moss specimen from an advanced group.Materials and Met…

Identifying Single DNA Barcode Regions of Oreochromis niloticus of Shahpura Lake, Bhopal and their Contribution to a Reference Library

Deepak Raghuwanshi Garg, Rajkumar Garg, Roshini Khandait, Parul Jagdish, Vipin Vyas

pp. 221–228 · DOI: 10.5530/ajbls.2024.13.28 · Published

Background: The present investigation was carried out on the development of a barcode and DNA sequences database of Oreochromis niloticus (Nile Tilapia) of Shahpura Lake, Bhopal through mitochondrial Cytochrome c Oxidase…

Comparative Phytochemical Analysis of Two Wound Healing Flora

Sreeranjini Kundamveettil Post-Graduate

pp. 229–234 · DOI: 0.5530/ajbls.2024.13.29 · Published

Chromolaena odorata (L.) R.M. King & H. Rob., shrub of Family Asteraceae and Hemigraphis alternata (Burm.f.) T.Anderson, herb of Family Acanthaceae are widely used as wound healers in local medicine. The leaf extract of …

Comparative Phytochemical Analysis of Curcuma aromatica, C. aeruginosa and C. angustifolia.

Sreeranjini Kundamveetil Post Graduate

pp. 235–240 · DOI: 10.5530/ajbls.2024.13.30 · Published

Curcuma, species of Family Zingiberaceae valued economically due to medicinal and commercial properties ; three species of which viz.,Curcuma aromatica, C. aeruginosa and C. angustifolia was analysed for phytochemical co…

Antibacterial Activity and Sensory Profile of Liquid Hand Soap from Arabica (Coffea arabica) and Robusta (Coffea canephora) Spent Coffee Grounds.

Liezl Teopiz Asido, Cyndrelle Gene Unico, Richard Khylle Lim Torniado, Trixie Marie Rivero Villacencio, Ian Jay Paspe Saldo

pp. 241–249 · DOI: 10.5530/ajbls.2024.13.31 · Published

Aim/Background: The increasing consumption of coffee worldwide generates thousands of leftover coffee grounds that, when disposed of, damage the environment. The goal of this research was to create liquid hand soap from …

Sonerila periyarensis sp.nov.-A new species of Melastomataceae from Kerala, India

Deepthy Kumary Kunjukrishna Pillai, Sreekala Appukuttan Nair Kamalabhai, Usha Vikraman Pillalai Sarojini Amma, Raju Ramasubbu

pp. · DOI: 10.5530/ajbls.2024.13.9 · Published