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Indian Journal of Pharmaceutical Education and ResearchNOW IN
Article

Antiobesity Potential of Fresh Cow Urine and its Distillate - A Biomedicine for Tomorrow

Sanjay Sharma1★, Ketan Hatware1, Ashwini Deshpande1, Payal Dande1, Sravani Karri1★ Corresponding author

  1. 1NMIMS, School of Pharmacy and Technology Management, Shirpur, Maharashtra, INDIA.

CORRESPONDENCE

Sanjay Sharma

NMIMS, School of Pharmacy and Technology Management, Shirpur, Maharashtra, INDIA.

sanjay.sharma@nmims.edu

Received: 17-08-2017; Revised: 04-09-2017; Accepted: 28-10-2017.

Volume 51, Issue 4S · pp. s712–s721 · PUBLISHED 2017 · DOI: 10.5530/ijper.51.4s.103

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ABSTRACT

Background: The cow urine has been used traditionally for the management of many diseases and also used as bio-enhancer to improve their therapeutic effect. Objective: To prepare and evaluate the anti-obesity potential of distillate cow urine and compare with fresh cow urine against high fat diet induced obesity in Wistar rats. Materials and Methods: Qualitative analysis of fresh cow urine and its distillate was done and used for the evaluation of assessment of anti-obesity parameters like BMI, abdominal circumference, obesity index, atherogenic index, lipid profile analysis and histopathological evaluation after two months daily oral treatment against high fat diet induced Obesity. Results: The treated groups with fresh cow urine and its distillate has reduced BMI, abdominal circumference, obesity index, atherogenic index, total cholesterol, triglycerides, LDL-C and VLDL-C Significantly while increased the levels of HDL-C as compared with control group (P<0.05). The Histopathological evaluation revealed the size of visceral white adipose tissue in treated groups was reduced as compared with control Group. Conclusion: In the present research conclude that fresh cow urine and its distillate both are having significant anti-obesity activity against high fat diet induced obesity in Wistar rats.

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    Sharma, S., Hatware, K., Deshpande, A., Dande, P., & Karri, S. (2017). Antiobesity Potential of Fresh Cow Urine and its Distillate - A Biomedicine for Tomorrow. Indian Journal of Pharmaceutical Education and Research, 51(4S), s712–s721. https://doi.org/10.5530/ijper.51.4s.103