Volume 53, Issue 4S

Original Article(continued)

1. Article

   One Step Towards: The Synthesis of Optimized Coumarin Derivatives as an Anti-HIV Agent

   Vikas Kumar, Indra Prashad Pandey, Jainendra Jain, Ram Babu Tripathi

   pp. s624–s629 · DOI: 10.5530/ijper.53.4s.158 · 2019

   The development for the sustainable approach was a key ingredient for the research, especially in the field of drug development against HIV. Several attempts have been made in the positive direction for the treatment of …

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2. Article

   Stress Degradation Studies of Riociguat, Development of Validated Stability Indicating Method, Identification, Isolation and Characterization of Degradation Products by LC-HR-MS/MS and NMR Studies

   Charu P Pandya, Sadhana J Rajput

   pp. s630–s641 · DOI: 10.5530/ijper.53.4s.159 · 2019

   Aim: The present study reports the degradation behavior of new antihypertensive drug Riociguat under various stress conditions as per International Conference on Harmonization guidelines ICH, Q2(R1). Materials and Method…

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3. Article

   Development and Validation of Genotoxic Impurity in Esomeprazole Magnesium Trihydrate Active Pharmaceutical Ingredient by LC-MS/MS

   Suresh Reddy Yelampalli, Venkata Shanmukha Kumar Jagarlapudi, Useni Reddy Mallu

   pp. s642–s649 · DOI: 10.5530/ijper.53.4s.160 · 2019

   Objectives: A rapid, sensitive and selective analytical method has been developed and validated by liquid chromatography tandem Mass spectrometry (LC-MS/MS) for the quantification of traces of Cumene Hydroperoxide in Eso…

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4. Article

   Potential Effect of Steroidal Alkaloids from Sarcococca saligna against Leishmania tropica

   Naeem Ullah Jan, Bashir Ahmad, Muhammad Kifayatullah, Haroon Rahim, Fazli Amin

   pp. s650–s654 · DOI: 10.5530/ijper.53.4s.161 · 2019

   Background and Objectives:Sarcococca species have a rich source of steroidal alkaloids that possess different biological and pharmacological activities. Hence, present research was design to isolate the steroidal alkaloi…

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5. Article

   Novel Chroman Analogs as Promising Heterocyclic Compounds: Their Synthesis and Antiepileptic Activity

   Pinki Rawat, Saurabh Manaswita Verma, Piyush Kumar

   pp. s655–s665 · DOI: 10.5530/ijper.53.4s.162 · 2019

   Aim: New series of novel chroman analogs was designed and synthesized using appropriate synthetic route. Materials and Methods: Structures of synthesized chroman hydrazides fused with different anhydrides were supported …

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6. Article

   Complimentary Effects of Curcumin for Enhancing Efficacy of Acetylsalicylic Acid against Prostate Cancer

   Tapas Kumar Mohapatra, Debasish Mohapatra, Bharat Bhusan Subudhi

   pp. s666–s677 · DOI: 10.5530/ijper.53.4s.163 · 2019

   Background: Prostate cancer is the 6th leading cause of cancer death worldwide. Androgen Deprivation Therapy (ADT) in prostate cancer enhances the risk of Rheumatoid Arthritis (RA). Acetylsalicylic Acid (ASA) can be pote…

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7. Article

   Cassia auriculata L.: An Ethno Medical Approach in Exploring Anti-solar Efficacy

   Krantisinha Hanumant Randive, Ravindra Durdundayya Hiremath, Amolkumar Ashok Kempwade, Anagha Ashok Patil

   pp. s678–s683 · DOI: 10.5530/ijper.53.4s.164 · 2019

   Objectives: The present study deals with an in-vitro screening for the anti-solar potential of aqueous and ethanolic extracts of Cassia auriculata using the UV method. Methods: Aqueous and ethanolic extracts were prepare…

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8. Article

   Analgesic and Anti-allodynic Effects of Two Flavonoids in Partial Sciatic Nerve Ligation in Rat Model

   A.C. Rana, Bhawna Gulliya, Swati Rana

   pp. s684–s690 · DOI: 10.5530/ijper.53.4s.165 · 2019

   Background: Flavonoids, also called as bioflavonoids, are secondary metabolites of plants. Flavonoids, curcumin and hesperidin, possess various pharmacological activities such as analgesic, anti-ulcer, anti-parkinson, an…

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9. Article

   Stability-Indicating RP-HPLC Method for the Quantification of Paliperidone in Bulk and Solid Dosage Form to Establish Validation and Stability Indicating Parameters

   Sadashivaiah Rudragangaiah, Rohith Ganapathi Bhatta, Satheesha Babu Birur Kotappa

   pp. s691–s698 · DOI: 10.5530/ijper.53.4s.166 · 2019

   Objectives: In the present research work, stability indicating reverse phase high performance liquid chromatography method was developed and validated for the quantification of paliperidone in bulk and solid dosage form.…

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10. Article

    Analytical Quality by Design Assisted HPLC Method for Quantification of Canagliflozin/ Metformin and Stability Studies

    Sunitha Gurrala, Shivaraj Shivaraj, CVS Subrahmanyam, Panikumar Durga Anumolu, Gowthami Saraf

    pp. s699–s709 · DOI: 10.5530/ijper.53.4s.167 · 2019

    Aim: Current work entails the analytical quality by design (AQbD) based robust HPLC method for real-time analysis of canagliflozin and metformin. Different pKa values of two drugs made their chromatographic separation cr…

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11. Article

    Pharmacognostical and Proximal Analysis of Two different Extracts (Methanol and Aqueous) of Indian Endangered Coscinium fenestratum Stem

    Kuntal Das

    pp. s710–s720 · DOI: 10.5530/ijper.53.4s.168 · 2019

    Background: Coscinium fenestratum (CF) (Family: Menispermaceae), an endangered and highly commercial medicinal plant of traditional system of medicine. Stem is commercially important which have multiple medicinal used an…

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