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Indian Journal of Pharmaceutical Education and ResearchNOW IN
Review

Biomaterials in 3D Printing: A Special Emphasis on Nanocellulose

Ravindra Vijay Badhe1★, Anagha Godse1, Ankita Ahinkar1★ Corresponding author

  1. 1Department of Pharmaceutical Quality Assurance, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, Maharashtra, INDIA.

CORRESPONDENCE

Ravindra Vijay Badhe

Department of Pharmaceutical Quality Assurance, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, Maharashtra, INDIA.

ravindra.badhe@dypvp.edu.in

Received: 07-08-2019; Revised: 22-02-2020; Accepted: 19-05-2020.

Volume 54, Issue 3 · pp. 526–540 · PUBLISHED 2020 · DOI: 10.5530/ijper.54.3.101

View on IJPER original site ↗

ABSTRACT

Aim and Background: The main objective of this review is to highlight nanocellulosic materials in 3D bioprinting. Three-dimensional (3D) bioprinting is on the verge of fabricating the artificial organ and living tissues. For the target construction the process of this 3D bioprinting involves layer-by-layer deposition of suitable biomaterials using predesigned data made by using Computer Aided Design (CAD) as an outline. However, only a handful of biomaterials are able to fulfil the considerable requirements for suitable bioink formulation, which is a critical component of efficient 3D bioprinting. Conclusion: Cellulose, a naturally occurring polysaccharide, is clearly the most commonly employed material in current bioinks. Here, in this review we discuss the advantages, reasons, applications, disadvantages of the use of cellulosic bioink in 3D bioprinting by summarizing the most recent studies that used cellulose for printing vascular tissue, bone and cartilage. In addition, other breakthroughs in the use of cellulose in bioprinting are discussed, including strategies to improve its structural and degradation characteristics. In this review, we organize the available literature in order to inspire and accelerate novel cellulose-based bioink formulations with enhanced properties for future applications in basic research, drug screening and regenerative medicine.

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    Badhe, R. V., Godse, A., & Ahinkar, A. (2020). Biomaterials in 3D Printing: A Special Emphasis on Nanocellulose. Indian Journal of Pharmaceutical Education and Research, 54(3), 526–540. https://doi.org/10.5530/ijper.54.3.101